Specialization of the journal is the legal sphere. The pages of the electronic journal will be published articles by national and foreign authors on current achievements and future prospects in the field of legal science. The electronic journal will cover the ongoing democratic reforms in the country, mainly the tasks outlined in the Strategy of Action for the five priority development directions…
- Polymorphism of the mthfr C677T gene and its clinical and prognostic significance in COVID-19– associated ischemic stroke
Ибодов Бекзод Абдусатторович, Туйчибаева Нодира Мираталиевна, Азизова Раьно Бахадировна, Эгамов Хусен Эркинович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
This study was aimed at investigating the genetic, clinical, and laboratory parameters associated with the development of ischemic stroke in the context of COVID-19 infection. The study included 240 patients treated in…
- Anxiety disorders in parkinson's disease and their relationship with depression
Наимов Олим Юнусович, Матмуродов Рустамбек Жуманазарович, Муминов Бекзод Аскарович, Жуманазарова Шахзода Рустамбековна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
Anxiety disorders are among the most common psychoemotional disorders in Parkinson's disease. The level of anxiety may depend on a number of factors. The оbjective of the study was to investigate the characteristics of…
- Analysis of etiological causes and risk factors of cerebrovascular stroke in ecologically unfavorable regions of the republic of karakalpakstan
Тлеубергенова Азима Балтабаевна, Раманова Юлдузхан Бисенбаевна, Матмуродов Рустамбек Жуманазарович, Жуманазарова Шахзода Рустамбековна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
One of the most pressing issues in modern neurology is cerebrovascular disease. This is due to the high mortality and disability associated with stroke. Objective. To study the prevalence, etiology, and risk factors for…
- Features of the clinical picture and structural changes during migration in fertility-aged women with an assessment of predicting factors
Камалова Малика Илҳомовна, Қудратова Нигора Бурхоновна, Абдуллаева Муаззамхон Илҳомидиновна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
Migraine is one of the most common primary headaches characterized by recurrent attacks of pulsating headaches, often accompanied by nausea, vomiting, photophobia, and phonophobia. According to the World Health…
- Clinical symptoms of transitionary ischemic attacks in the elderly
Бахадирова Муниса Анваровна, Назарова Жанна Авзаровна, Исамухамедова Севара Юсуфовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
Transient ischemic attacks (TIA) are one of the most pressing problems in modern neurology and geriatrics. According to the World Health Organization, TIA is characterized by sudden focal neurological deficit due to…
- Clinical and pathophysiological characteristics of coordination disorders in sensorineural hearing loss in childhood
ЗОИРОВ Назиржон Маматович, ГАЙБИEВ Акмал Ахматжонович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
Coordination disorders in sensorineural hearing loss in childhood represent one of the most pressing and complex problems in modern pediatrics, otolaryngology, and neurology. Sensorineural hearing loss is a leading…
- Scientific analysis of radiomorphologic correlations between histomorphological alterations and modern neuroimaging data in traumatic brain injury
Мамажанов Бохадиржон Солижанович, Норов Абдурахмон Убайдуллоевич, Холиков Шавкатбек, Алибеков Омадбек Озодбекович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
This study investigates the correlation between histological alterations and modern neuroimaging findings (MRI and CT) in traumatic brain injury (TBI). Autopsy and imaging data of 40 patients (2023–2024) were analyzed…
- Histomorphological changes and thanatogenesis basis in fatal cases caused by traumatic brain injuries
Холиков Шавкатбек, Алибеков Омадбек Озодбекович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
This study presents a forensic histological analysis of brain tissue obtained from 43 patients who died as a result of traumatic brain injury. Histomorphological examination revealed a high frequency of perivascular…
- Comparison of methods for detecting kappa free light chains and oligoclonal bands in cerebrospinal fluid for the diagnosis of multiple sclerosis
Абдулазизова Умидахон Салохиддин кизи, Мусаева Юлдуз Альписовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
The aim of this study was to evaluate the diagnostic accuracy of detecting kappa free light chains (KFLC) in cerebrospinal fluid for the diagnosis of multiple sclerosis, in comparison with isoelectric focusing (IEF) for…
- Chronic stress as a pathogenetic factor of chronic brain ischemia: results of a comprehensive clinical and biochemical study
АБДУЛЛАEВА Наргиза Нурмаматовна, АБДУЛЛАEВА Азиза Ферузовна, ДЖУРАБЕКОВА Азиза Тахировна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
Chronic cerebral ischemia (CCI) is one of the most pressing problems of modern neurology, characterized by persistent impairment of cognitive functions and a significant decrease in the quality of life of patients…
- Efficiency of hemoreologic parameters correction in patients with risk factors for cerebrovascular diseases AT outpatient medical rehabilitation stage
Рахимкулов Азамат Салаватович, Мавлянова Зилола Фархадовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
The article presents the efficiency of balneology correction of hemoreologic parameters in patients with risk factors for cerebrovascular diseases at outpatient medical rehabilitation stage. Application of balneological…
- The importance of «Brain-computer» interfaces in neurorehabilitation for outcomes of traumatic brain injuries (literature review)
Алиев Мансур Абдухоликович, Мамадалиев Абдурахмон Маматкулович, Ярмухаммедова Наргиза Анваровна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
In recent years, advances in brain-computer interface technologies have ushered in a new era in the restoration and rehabilitation of neurological functions. These technologies aim to enable individuals with disabling…
- Юз симпаталгияларининг патогенетик, клиник-қиёсий хусусиятлари ва диагностик мезонлари
Абдуллаева Муборак Беккуловна, Ядгарова Лола Баҳодировна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-16
Facial Sympathalgia is one of the pain syndromes affecting the facial region, primarily developing in connection with dysfunction of the autonomic nervous system. This condition arises under the influence of various…
- Pathogenetic interconnections of inflammation, dyslipidemia in atherotrombotic damage of extracranial arteries
Абдулаева Наргиза Нурмаматовна, Юлдашев Сардорбек Икромович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-16
Atherothrombotic damage to the extracranial arteries is one of the most important medical and social problems of our time, being the leading cause of the development of ischemic cerebrovascular events. According to the…
- Comprehensive analysis of neurophysiological changes in patients using opioid drugs
Абдукодиров Элдор Исроилович, Жамалова Шахло Авазжон қизи · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-16
This article comprehensively studies the neuropsychological changes observed in patients who have taken opioid drugs for a long time. The study analyzed disorders in cognitive functions (memory, attention, thinking and…
- Clinical and comparative characteristics, diagnostic criteria and methods of treatment of tunnel neuropathies
Абдукодиров Элдор Исроилович, Миразикова Фарзона Юлдашевна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-16
In this scientific work, the possibilities of early diagnosis of tunnel neuropathy were analyzed, clinical trials were compared, and modern instrumental methods of diagnosis and treatment were developed. Tunnel…
- Патогенетические взаимосвязи воспаления, дислипидемии при атеротромботическом поражении экстракраниальных артерий
Абдулаева Наргиза Нурмаматовна, Юлдашев Сардорбек Икромович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-16
- Comprehensive diagnosis of weather sensitivity in patients with cerebrovascular diseases
Худайберганов Нурмамат Юсупович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-16
The article addresses the pressing issue of diagnosing weather sensitivity in patients with cerebrovascular diseases. A comprehensive approach is presented, integrating assessment of neurological status, autonomic…
- Autism spectrum disorders - etiopathogenetic aspects, varieties of nosological manifestations, patient management (overview)
Назаров Алишер Илхомович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-16
The article describes the definition of autism spectrum disorders (ASD), reveals the relevance of the problem of autism spectrum disorders in children, and presents a modern perspective on the possible etiological and…
- The role of hyperhomocysteinemia in the pathogenesis of post-traumatic encephalopathy
Хайдаров Нодир Қодирович, Хикматова Шахзода Шухратовна, Собирова Саодат Кароматовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-16
Post-traumatic encephalopathy (PTE) is one of the most frequent and socially significant consequences of craniocerebral trauma, accompanied by cognitive and emotional impairments. In recent years, special attention has…
- Efficiency of osteopathic therapy in vertebral artery syndrome
Саидов Сухроб Рустамович, Ўринов Мусо Болтаевич · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-16
Vertebrogenic vertebral artery syndrome (VAS) is one of the most common reasons for patients to consult an osteopathic physician. This study presents data on the classification, pathophysiological mechanisms, clinical…
- Clinical and biochemical changes after stroke AT the outpatient stage
Саломова Нилуфар Каххаровна, Жамолов Шариф Шухратович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-16
Ischemic stroke remains one of the leading causes of disability and mortality. In a study of 287 patients, it was shown that functional recovery depends not only on clinical but also on social factors. In the early…
- Results of molecular genetic research polymorphism of the Vegf rs699947 gene in cancer
Рахматова Санобар Низамовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-16
In patients with Acute cerebrovascular accident, the percentage of S/S, S/A, and A/A genotypes was 12.3%, 43.4%, and 44.3%, respectively, while in patients with Acute cerebrovascular accident, these indicators were…
- Gender specificity of coping strategies in men and women
Уринов Мусо Болтаевич, Дагаева Дилфуза Ботировна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-16
The effectiveness of stress coping depends not only on the success of the chosen strategy but also on individual characteristics of the person. Age, sex, social status, and gender identity influence coping ability and…
- Neurophysiological features of vestibular migraine
Ахророва Шахло Ботировна, Камалова Феруза Умаровна, Мухсинов Мухаммад Мирзо Мирсаидович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-16
A review of domestic and international literature over the past 10 years was conducted, focusing on the neurophysiological features of vestibular migraine. It has been shown that activation of the trigeminovascular…
- Endothelial and neuronal markers in the diagnosis and prediction of preeclampsia
Рахматуллаева Гулнара Кутбитдиновна, Худаярова Севара Муратбековна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-14
Preeclampsia (PE) remains one of the leading causes of maternal and perinatal morbidity and mortality. The key mechanism of its pathogenesis is endothelial dysfunction associated with an imbalance between pro- and…
- Early hormonal therapy in dee-swas: opportunities for improving cognitive and clinical outcomes
Шохимардонов Шохижахон Шохимардонович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-14
Developmental and epileptic encephalopathy with spike-wave activation in sleep (DEE-SWAS) is a severe childhood disorder characterized by frequent epileptic seizures, cognitive decline, and behavioral regression…
- Clinical and neurological features and risk factors of preeclampsia
Рахматуллаева Гулнара Кутбитдиновна, Худаярова Севара Муратбековна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-14
Preeclampsia (PE) is a multisystem complication of pregnancy that remains one of the leading causes of maternal and perinatal mortality. The disease is characterized by a combination of arterial hypertension and target…
- Optimization of diagnostics and targeted therapy approaches for continuous spike-wave activity during sleep in patients with epileptic encephalopathy
Шохимардонов Шохижахон Шохимардонович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-14
The article discusses modern approaches to diagnostics and targeted therapy in patients with epileptic encephalopathy presenting with continuous spike-wave activity during sleep (DEE-SWAS). Considering the complexity…
- Патогенетические особенности, классификация, диагностика поражения нервной системы при туберкулезе
Паноева Нилуфар Хамроевна, Саноева Матлюба Жахонкуловна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-14
The article is devoted to the relevance of the tuberculosis process due to its multi-organ impact on organs and systems, the pathogenesis of neurological changes, and the damage to the central and peripheral nervous…
- Clinical and neurophysiological analysis of sleep disorders in patients with arterial hypertension
Очилова Дилноза ойбек кизи · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-14
The review is devoted to a topical and socially significant problem of modern healthcare. As a result of studying 31 literary sources, the state of the issue of how healthy sleep affects blood pressure, and what is the…
- Cephalgic syndrome and its clinical, neurological, and paraclinic features in children with post-traumatic encephalopathy
Насирова Дилфуза Шовкатовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-14
In recent years, there has been an increase in craniocerebral injuries in children, among which mild craniocerebral injuries account for 78% to 86%. In the long-term period, in 40-86% of cases, the formation of…
- Clinical, biochemical, and neuroimaging aspects of migraine dynamics in children and adolescents
Кадирова Робия Мираббасовна, Алиджанова Дурдона Абдуллажоновна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-14
Migraine is one of the most common neurological disorders, affecting 7.7% of children and adolescents in the general population. The disease may manifest as early as under three years of age. As children grow older, the…
- Clinical and biochemical features of ischemic stroke in young adults
Рахматова Санобар Низамовна, Джумаев Баходир Игамович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-14
Stroke is a major medical and social problem worldwide. In young patients, ischemic stroke may have a multifactorial and atypical course, but recovery potential is higher; in elderly patients, it is mainly associated…
- Features of cerebral blood flow and electrical activity changes in patients with tia and ischemic stroke
Рахматова Санобар Низамовна, Бердиев Мухаммаджон Қахрамон угли · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-14
Clinical, laboratory, and hemodynamic characteristics were studied in patients with transient ischemic attack (TIA) and ischemic stroke (IS). Objective: To identify risk factors influencing the course and outcome of…
- Clinical features of acute and chronic vertebrobasilar insufficiency
Ҳайдаров Нодир Қодирович, Абдуллаева Муборак Бекқуловна, Тилавова Ҳилола Одил қизи · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-10
The article presents an overview of current data on the clinical features of acute and chronic vertebrobasilar insufficiency (VBI). Pathogenetic mechanisms, main neurological syndromes, diagnostic approaches and current…
- Pathogenetic basis of chronic cerebral ischemia development in arterial hypertension
Ходжиева Дилбар Таджиевна, Саъдуллоева Кундуз Абдулло кизи · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-10
Chronic cerebral ischemia (CCI) is a common form of cerebrovascular disease (CVD) that leads to cognitive impairment and disability. The main risk factor is arterial hypertension. The pathogenesis of CCI is associated…
- Current issues of acuchery-neurological comportance of pregnant with epilepsia
Косимхожиева Фотима Тахировна, Ходжиева Дилбар Таджиевна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-10
Epilepsy is one of the most common chronic neurological diseases affecting approximately 65 million people worldwide. Among women of reproductive age, the prevalence of epilepsy is 0.3-0.8%, which corresponds to…
- The importance of studying neuronally specific enolase in the residual period of ischemic stroke
Ходжиева Дилбар Таджиевна, Наврузова Зарина Шодмоновна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-10
Neuronal-specific enolase (NSE) is one of the most informative biomarkers of neuron damage, the level of which reflects the severity of ischemic damage and the dynamics of recovery of brain tissue. In the acute period…
- Post-vaccination complications - myth or reality?
Жураева Дилрабо Нарзуллаевна, Саноева Матлюба Жахонкуловна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-10
This review article is dedicated to the problems of vaccination, their relevance. The necessity of vaccination is being proven, each of which has its own timing and requirements for implementation. Data from far abroad…
- The role of immune factors in the development of trigeminal nerve neuralgia
Ходжиева Дилбар Таджиевна, Жураева Дилсора Нуриддиновна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-09
We visited Bukhara region, Jondor District Medical Association, Central Polyclinic, where 92 patients with trigeminal neuralgia aged 17 to 70 years and 30 patients in the control group were prescribed interleukin -6…
- Neurological characteristics of maxillofacial traumas
Абдуллаева Муборак Беккуловна, Дадажонов Зиёвиддин Абдумухторович, Нурматова Қурбоной Чориевна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-09
Due to the increasing frequency and severity of injuries, the present article analyzes the etiology and nature of modern injuries leading to acute traumatic injuries of the maxillofacial region. 100 patients with acute…
- Қандли диабет II типи билан оғриган беморларда когнитив дисфункциянинг ривожланишида цереброваскуляр бузилишнинг аҳамияти
Давронова Хилола Завкиддиновна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-09
Cerebrovascular diseases are an important medico-social problem, which causes a lot of death and disability, and is currently becoming an economic problem with high costs. Diabetes mellitus is one of the main risk…
- Cognitive dysfunction and somatic pathology – etiopathogenesis, clinical approach, prospects
Гулова Мунисахон Афзаловна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-09
The article describes the physiological state of brain cognitive function, its pathology, cause-and-effect mechanisms of cognitive dysfunction development, and the epidemiological state of cognitive dysfunction in…
- Influence of hemorrhagic and ischemic insults on the compensatory and adaptive properties of the organism during early rehabilitation
Рузиев Феруз Гиёсович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-09
120 patients were examined in the acute period of hemorrhagic stroke. All patients underwent subjective, objective, clinical-instrumental, and neuropsychological examinations, and in combination with treatment, 72…
- Early prevention of secondary complications and the role of antioxidant therapy after thrombolysis and thrombectomy in acute cerebrovascular accident
Бокиева Файзинисо Адхам кизи, Бахадирханов Мухамедшокир Мухамедкабирович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-09
The study included 80 patients who experienced an acute ischemic stroke and were hospitalized within the first 6 hours from symptom onset. The diagnosis was confirmed using neuroimaging methods (CT or MRI of the brain)…
- Pathogenetic role of glymphatic insufficiency in chronic cerebral ischemia
Ахророва Шахло Ботировна, Умарова Мехринисо Нуриддиновна, Мухсинов Мухаммад Мирзо Мирсаидович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-09
Chronic cerebral ischemia is accompanied by impaired function of the glymphatic system, leading to reduced clearance of metabolites and accumulation of toxic proteins (β-amyloid, tau protein). These changes aggravate…
- Chronic migraine and quality of life
Ахмедова Дилафруз Баходировна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-09
Chronic forms of headache significantly reduce the quality of life of patients, which affects physical, mental and social functions. This article reviews the impact of migraine, chronic tension headaches and cluster…
- Specifics of pain syndrome and rehabilitation approaches in parkinson’s disease
Ахророва Шахло Ботировна, Абдурасулов Сардор Султанмуродович, Мухсинов Мухаммад Мирзо Мирсаидович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-09
Pain syndrome is a common non-motor manifestation of Parkinson’s disease, observed in the majority of patients and significantly reducing their quality of life. The main forms include musculoskeletal, dystonic…
- Neurological and cognitive impairments in chronic obstructive pulmonary disease associations with cerebral hemodynamics and neuroimaging findings
Уринов Мусо Болтаевич, Тулаев Мирзохид Жалолович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-09
This study investigated neurological and cognitive alterations in 120 patients with different stages of COPD using clinical, neuropsychological assessments, transcranial Doppler ultrasonography, and MRI. Cognitive…
Ha. Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research O‘zbekiston Oliy attestatsiya komissiyasi (OAK) ro‘yxatidagi ilmiy jurnal — 361/5-sonli qaror (27 сентябрь 2024), ixtisoslik: 14.00.00 Тиббиёт фанлари.
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