Objective: To systematize current data on the role of transcutaneous vagus nerve stimulation (tVNS) in modulating neuroplasticity during post- stroke rehabilitation. Materials and Methods: Analyzed 44 publications (2015–2024) from PubMed, Scopus, Web of Science. Results: tVNS reliably enhances neuroplasticity through activation of the cholinergic anti-inflammatory pathway (reduction of IL-6, TNF-α by 40–60%), stimulation of the locus coeruleus-norepinephrine system (increase in norepinephrine by 35%), and modulation of BDNF (increase by 25–30%). Randomized trials (VNS-REHAB, n=108) demonstrated 40% improvement in motor functions (Fugl-Meyer) and 35% enhancement in cognitive scores (MoCA) when combining tVNS with rehabilitation. The method is safe: adverse effects rate does not exceed 5%. Conclusion: tVNS is a promising non-invasive neuromodulation method that potentiates neuroplasticity through multilevel mechanisms. Its inclusion in comprehensive rehabilitation programs for patients with motor and cognitive deficits after stroke is recommended, especially in cases resistant to standard therapy.
| Mualliflar | Адамбаев Зуфар Ибрагимович, Абдукаримова Угилой Ахмедовна |
|---|---|
| Jurnal | Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research |
| Nashriyot | Бухоро давлат тиббиёт институти |
| Nashr sanasi | 2025-11-19 |
| Jild | 6 |
| Son | 6/1 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-08-26 |
транскутанная стимуляция блуждающего нерва, нейропластичность, постинсультная реабилитация, двигательные нарушения, когнитивные нарушения, холинергическая система, нейромодуляция, transcutaneous vagus nerve stimulation, neuroplasticity, post-stroke rehabilitation, motor deficits, cognitive impairment, cholinergic system, neuromodulation, qon tomirining bulayuvchi nervining transkutan stimulyatsiyasi, neyroplastiklik, postinsult reabilitatsiya, harakat buzulishlari, kognitiv buzulishlar, kolinergik tizim, neyromodulyatsiya
| APA | Адамбаев Зуфар Ибрагимович, & Абдукаримова Угилой Ахмедовна (2025). TRANSCUTANEOUS VAGUS NERVE STIMULATION IN MODULATING NEUROPLASTICITY DURING POST-STROKE REHABILITATION (LITERATURE REVIEW). Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(6/1). https://tadqiqot.uz/index.php/neurology/article/view/12923 |
|---|---|
| GOST (OAK) | Адамбаев Зуфар Ибрагимович, Абдукаримова Угилой Ахмедовна TRANSCUTANEOUS VAGUS NERVE STIMULATION IN MODULATING NEUROPLASTICITY DURING POST-STROKE REHABILITATION (LITERATURE REVIEW) // Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research. – 2025. – T. 6, № 6/1. |
| MLA | Адамбаев Зуфар Ибрагимович, and Абдукаримова Угилой Ахмедовна. “TRANSCUTANEOUS VAGUS NERVE STIMULATION IN MODULATING NEUROPLASTICITY DURING POST-STROKE REHABILITATION (LITERATURE REVIEW).” Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(6/1), 2025. https://tadqiqot.uz/index.php/neurology/article/view/12923 |
| Chicago | Адамбаев Зуфар Ибрагимович, and Абдукаримова Угилой Ахмедовна. “TRANSCUTANEOUS VAGUS NERVE STIMULATION IN MODULATING NEUROPLASTICITY DURING POST-STROKE REHABILITATION (LITERATURE REVIEW).” Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(6/1) (2025). https://tadqiqot.uz/index.php/neurology/article/view/12923 |
| Harvard | Адамбаев Зуфар Ибрагимович, and Абдукаримова Угилой Ахмедовна (2025) ‘TRANSCUTANEOUS VAGUS NERVE STIMULATION IN MODULATING NEUROPLASTICITY DURING POST-STROKE REHABILITATION (LITERATURE REVIEW)’, Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(6/1). https://tadqiqot.uz/index.php/neurology/article/view/12923 |
| BibTeX | @article{article2025,
title = {TRANSCUTANEOUS VAGUS NERVE STIMULATION IN MODULATING NEUROPLASTICITY DURING POST-STROKE REHABILITATION (LITERATURE REVIEW)},
author = {Адамбаев Зуфар Ибрагимович and Абдукаримова Угилой Ахмедовна},
journal = {Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research},
year = {2025},
volume = {6},
number = {6/1},
url = {https://tadqiqot.uz/index.php/neurology/article/view/12923}
} |
Boshqa maqola uchun iqtibos tayyorlash
This study conducted a comparative analysis of parameters in patients with ischemic and hemorrhagic stroke hospitalized in the Fergana region. The work examined the gender and age structure of patients, mortality rates…
The study included 143 patients with lacunar stroke, 54 of whom had COVID-19 infection. A comparative analysis of the clinical manifestations, course variants, and severity of asthenic syndrome in patients with lacunar…
A prospective interventional study was conducted involving 30 school-age patients with a confirmed diagnosis of cerebral palsy who underwent rehabilitation in medical institutions of the Andijan region between 2023 and…
Obstructive sleep apnea (OSA) is recognized as an independent risk factor for the development of cognitive impairment. Recent evidence (Andreu et al., Sleep Medicine Reviews, 2024) [1]. indicates that intermittent…
Chronic alcoholism remains one of the most significant medical and social problems of modern society. According to WHO data, more than 280 million people worldwide suffer from alcohol dependence, with a persistent trend…
Stroke is an acute cerebrovascular accident resulting in persistent focal brain damage. Post-transcriptional regulators of gene expression can signal the severity of the disease, thereby facilitating timely treatment…
This review systematizes current data on the epidemiology, clinical presentation (cyanotic and pallid types), diagnosis (history + iron deficiency screening), and treatment of affective-respiratory attacks (ARAs)…
The article presents a comprehensive analysis of the problem of neurological disorders in term small-for-gestational-age (SGA) infants, a group at high risk for adverse outcomes. The pathogenetic mechanisms of central…
Objective: To systematize data on the role of MRI-detected markers of cerebral microangiopathy (CMA) in predicting cognitive impairment and risk of recurrent vascular events in patients during the long-term period after…
The article presents the results of a correlation analysis aimed at identifying the structure of interrelationships and pathogenetic patterns of neurological manifestations in spinal pathology. The study established the…
Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research — barcha maqolalar · 2025-yil arxivi
Modic changes are pathological changes in the vertebrae and its end plates in the form of bone marrow edema, fatty degeneration or osteosclerosis, detected by magnetic resonance imaging (MRI). The main clinical picture…
In 2023, an annual screening of geomagnetic activity by month was carried out and its effect on the development of cerebral strokes depending on geomagnetic activity was analyzed. It was found that high geomagnetic…
The article presents a modern classification of back pain and differentiated management tactics for patients with various types of dorsalgia. The tactics of management and preference for the choice of drugs…
The article presents modern information on discogenic lumbosacral radiculopathy, its etiopathogenesis, prevalence, clinical picture, diagnostics, treatment, rehabilitation and prevention. The article will undoubtedly be…
110 patients with spinal stenosis of the cervical spine were examined. The clinical picture differs with polymorphism of combinations of reflex, radicular and spinal syndromes, reflecting multiple and multilevel…
Examination and treatment of 120 elderly patients with degenerative-dystrophic diseases of the spine (DDDS) were carried out. On the basis of CT and / or MRI examination of the spine, the patients were divided into…
Настоящее исследование посвящено разработке алгоритма раннего выявления сенсоневральной тугоухости у детей с использованием методов полимеразной цепной реакции (ПЦР). Обследовано 235 детей с нарушениями слуха, из…
В статье представлены клинические аспекты и диагностические проблемы выявления сенсоневральной тугоухости у новорождённых с перинатальной патологией. Обследовано 115 новорождённых, из которых 35 перенесли асфиксию, а у…
Сенсоневральная тугоухость (СНТ) у детей остаётся одной из наиболее актуальных проблем современной оториноларингологии и медицинской генетики. Ранняя диагностика нарушений слуха играет ключевую роль в предупреждении…
Сенсоневральная тугоухость у новорождённых является одной из ведущих причин нарушения слухоречевого развития и ранней инвалидизации. Наиболее уязвимыми считаются дети, перенёсшие перинатальные осложнения, такие как…
Mazkur eksperimental tadqiqotda yuqori yog‘li ratsion va seftriaksonning lipid hamda uglevod almashinuviga alohida va birgalikdagi ta’siri 160 ta oq zotsiz erkak kalamushda o‘rganildi. Tajriba hayvonlari to‘rtta guruhga…
Мазкур тадқиқотда Тошкет вилоятидаги Ўрта Чирчиқ тумани 25-сонли, Бўка тумани 3-сонли ва 9-сонли давлат мактабгача таълим ташкилотларида 2025 йил ёз мавсумидаги таомномаларнинг озиқ-овқат маҳсулотлари билан…