STRUCTURE OF INTERRELATIONSHIPS AND PATHOGENETIC PATTERNS OF NEUROLOGICAL MANIFESTATIONS IN SPINAL PATHOLOGY: BASED ON CORRELATION ANALYSIS OF CLINICAL-BIOCHEMICAL INDICATORS
The article presents the results of a correlation analysis aimed at identifying the structure of interrelationships and pathogenetic patterns of neurological manifestations in spinal pathology. The study established the presence of a structured network of correlations between clinical symptoms and the levels of key biochemical markers. The key scientific result was the identification of two interconnected but relatively independent pathogenetic processes: degenerative (MMP-mediated) and inflammatory-neuropathic (CRP/IL-6-mediated). The obtained data convincingly confirm the necessity of a comprehensive assessment of patients, taking into account both indicated components of pathology.
Абдуллаева Муборак Бекқуловна, Дадажонов Зиёвуддин Абдумухтор угли · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
В исследовании изучена динамика качества жизни (КЖ) и предрасположенности к лечению у 315 больных с ТНН. По данным опросника MOS SF-36 физический компонент КЖ после лечения увеличился с 28 до 58 баллов, психологический…
Мирджураев Эльбек Миршавкатович, Охунов Иброхимджон Усмонали огли · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
Objective: To systematize data on the role of MRI-detected markers of cerebral microangiopathy (CMA) in predicting cognitive impairment and risk of recurrent vascular events in patients during the long-term period after…
ДЖУРАБЕКОВА Азиза Тахировна, ХАЛИМОВ Фарзод Зафар угли, АБДУЛЛАЕВА Наргиза Нурмаматовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
Meningoencephalitis and encephalitis of various etiologies represent a serious problem in modern pediatrics and pediatric neurology, characterized by a high frequency of severe neurological consequences and disability…
Каримова Гулхумор Латифжон кизи · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
The article presents a comprehensive analysis of the problem of neurological disorders in term small-for-gestational-age (SGA) infants, a group at high risk for adverse outcomes. The pathogenetic mechanisms of central…
Асадов Хамидулла Фатхуллаевич · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
Surgical treatment of migraine has gained increasing importance in recent years as an effective method for patients who do not respond to medication therapy. This study analyzes the clinical outcomes of supraorbital…
Маджидова Ёкутхон Набиевна, Адамбаев Зуфар Ибрагимович, Камолдинова Дилдора Бахтияровна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
This review systematizes current data on the epidemiology, clinical presentation (cyanotic and pallid types), diagnosis (history + iron deficiency screening), and treatment of affective-respiratory attacks (ARAs)…
Холматов Расулжон Иброхимжон угли, Абдукадиров Улугбек Тахирович, Рахимбаева Гулнора Саттаровна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
Migraine remains one of the most common and socially significant neurological disorders, characterized by a high rate of chronification and disability among patients. Despite advances in modern pharmacotherapy, a…
Газиева Шахида Рустамовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
Stroke is an acute cerebrovascular accident resulting in persistent focal brain damage. Post-transcriptional regulators of gene expression can signal the severity of the disease, thereby facilitating timely treatment…
Эргашева Мафтуна Озодовна, Эргашев Сухроб Саидович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
Cerebral palsy (CP) is a group of permanent disorders affecting the development of movement and posture, causing activity limitations, which are associated with non-progressive disturbances that occurred in the…
Адамбаев Зуфар Ибрагимович, Абдукаримова Угилой Ахмедовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-11-19
Objective: To systematize current data on the role of transcutaneous vagus nerve stimulation (tVNS) in modulating neuroplasticity during post- stroke rehabilitation. Materials and Methods: Analyzed 44 publications…