Specialization of the journal is the legal sphere. The pages of the electronic journal will be published articles by national and foreign authors on current achievements and future prospects in the field of legal science. The electronic journal will cover the ongoing democratic reforms in the country, mainly the tasks outlined in the Strategy of Action for the five priority development directions…
- Dopamine deficiency in parkinson`s disease and its effect on movement
Бафоева Зарина Бахтиёровна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-08
Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects motor and cognition functions. The etiology of Parkinson's disease remains largely unknown, but genetic and environmental factors are…
- Clinical characteristics of autonomic symptoms in migraine and fibromyalgia comorbidity
Мавлонова Дилноза Баходировна, Азизова Раъно Баходировна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-08
Migraine and fibromyalgia are chronic pain syndromes that frequently co-occur and significantly reduce patients' quality of life. The aim of this study was to identify and compare the clinical characteristics of…
- New approaches to the migraine pathogenesis (review)
Холмуратова Бахтигул Нурмухуммедовна, Рашидова Нилуфар Сафоевна, Халимова Ханифа Мухсиновна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-08
Migraine is one of the most common neurological diseases in the world, and according to statistics, it ranks second among diseases that cause disability. We all know that this disease is several times more common in…
- Analysis of sadhd-i survey bats in kindergarten-aged children with hyperactive and attention deficit hyperactive
Мадиримова Латофат Оллабергановна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-08
In this article, 90 children were monitored, with complaints relating to hyperactivity and attention deficit syndrome, the average age of children was 4.5+0.1, of which 50 (55.6%) were boys, 40 (44.4%) were girls, and…
- Insulin resistance and inflammatory biomarkers as predictors of functional outcome in acute ischemic stroke
Қутлибика Абдурахмонова, Гулнора Рахимбаева Саттаровна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-08
This article evaluates the predictive role of insulin resistance and inflammatory biomarkers in patients with acute ischemic stroke. The study demonstrates that biomarker concentrations vary across stroke subtypes and…
- Fighting the tremor: how physical exercise slows the progression of parkinson's disease
Ахунова Тамина Адыл кизи · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-08
This article analyzes the role of physical exercise in slowing the progression of Parkinson's disease and alleviating its symptoms. Clinical studies have shown that exercise positively affects brain plasticity, dopamine…
- Efficacy and safety of microdiscectomy in the treatment of lumbar intervertebral disc herniation: clinical outcomes and comparative analysis
Норов Абдурахмон Убайдуллаевич, Алихонов Окилхон Шухратмирза угли · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-08
Lumbar intervertebral disc herniation is among the most common pathologies in modern neurosurgery, often associated with pain syndrome and neurological deficit, leading to a significant decline in patients’ quality of…
- The role of gut microbiota in the development of neurological disorders in children
Давлетова Шахноза Бахтиёр кизи · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-08
This review article summarizes current data on the role of gut microbiota in the development of neurological disorders in children. It discusses the formation and age-specific dynamics of gut microbiota, its…
- Немедикаментозная коррекция вегетативных нарушений у пациентов с хронической головной болью напряжения
Дьяконова Е.Н, Макерова В.В · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-08
Purpose: To evaluate the possibility of using breathing exercises with vocal exercises to correct autonomic disorders in patients with chronic tension headache. Materials and methods: A study was conducted of 120…
- Особенности церебрального кровотока у пациентов с эпизодической и хронической головной болью напряжения
Макерова В.В, Дьяконова Е.Н · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-10-08
Purpose: To determine the features of cerebral blood flow in patients suffering from episodic and chronic tension headache. Material and methods: 120 participants aged 25 to 44 years were included in the study, of which…
- Assessment of cognitive functions in patients with hypothyroidism
Оллаберганова Рохила Зохиржоновна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
This article examines the relationship between thyroid dysfunction and cognitive impairment, with a focus on hypothyroidism. The study involved 80 women with long-standing disease, divided into two subgroups: those with…
- Prediction of pain syndrome in postherpetic neuralgia based on clinical symptoms and blood biomarkers
Хайдарова Дилдора Кадировна, Сулаймонов Муроджон Насирович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Postherpetic neuralgia (PHN) represents one of the most severe complications of herpes zoster, characterized by persistent pain syndrome that significantly reduces patients' quality of life. Traditional approaches to…
- Modern perspectives on the characteristics and risk factors of progressive multifocal leukoencephalopathy in children (Literature Review)
ХУДОЙБЕРДИЕВА Диловар Имомназарова, НИЯЗОВ Шухрат Тошемирович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Progressive multifocal leukoencephalopathy (PML) has always been among the urgent issues in neurology and pediatrics, both in research and practice. In particular, neurological practice deals significantly with…
- The role of INTERLEUKIN-4 (IL-4) in trigeminal neuralgia
Ходжиева Дилбар Таджиевна, Жураева Дилсора Нуриддиновна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
We visited Bukhara region, Jondor District Medical Association, Central Polyclinic, where 92 patients with trigeminal neuralgia aged 17 to 70 years and 30 patients in the control group were prescribed interleukin -4…
- Pathophysiological bases of cognitive impairments in patients with chronic cerebral ischemia
Обидов Фаррух Хамитович, Мавлянова Зилола Фархадовна, Ким Ольга Анатольевна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
The article presents the results of determining the pathophysiological relationships between biomarkers of inflammation (IL-6, TNF-α, CRP), oxidative stress (MDA, homocysteine), neurodegeneration (NSE) and neurotrophic…
- Serotonergic mechanisms in the development of levodopa-induced motor and non-motor disorders in parkinson’s disease
Саидвалиев Фаррух Саидакрамович, Пулатова Дилёра Рустамовна, Хамидов Абдулахад Абдисаттарович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
150 patients were examined with Parkinson’s disease. All participants underwent a comprehensive clinical, neurological, and neuropsychological evaluation, including measurement of serotonin and dopamine levels in blood…
- Analysis of differential characteristics of clinical and functional changes in the early and prodromal stages of parkinson's disease
Сафаров Комилжон Камолович, Хайдарова Дилдора Кодировна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Parkinson's disease (PD) is one of the most common neurodegenerative diseases characterized by the progressive loss of dopaminergic neurons in the brain's substantia nigra. Traditionally, the diagnosis of Parkinson's…
- Clinical and morphological characteristics and risk factors of migrenia in women of fertile age (literature review)
Кудратова Нигора Бурхоновна, Абдуллаева Наргиза Нурмаматовна, Камалова Малика Ильхомовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Today, migraine is one of the most common and disabling neurological diseases. Migraine occurs 3 times more often in women than in men and affects 18-25% of women of fertile age. Hormonal changes, especially…
- Cervical myelopathy: pathophysiology, diagnosis, treatment strategy (literature review)
Мирджураев Эльбек Миршавкатович, Адамбаев Зуфар Ибрагимович, Маматханова Чарос Баходировна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Cervical myelopathy (CM) is a progressive neurological disorder caused by spinal cord compression in the cervical spine. The pathophysiology of CM is complex and involves a cascade of events such as spinal cord…
- Clinical and laboratory features of neurosyphilis in the era of antibiotic therapy
Абзоиров Кудрат Мусульмонкулович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Neurosyphilis is a form of late syphilis with central nervous system involvement that remains relevant in the era of modern antibiotic therapy. In recent decades, against the background of the HIV epidemic and the…
- Efficacy of neuroprotective drugs in the treatment of patients with ischemic stroke: modern strategies
Адамбаев Зуфар Ибрагимович, Киличев Ибодулла Абдуллаевич, Сапарбаев Кудрат Исмаилович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
The problem of ischemic stroke remains highly relevant in modern neurology due to its high mortality, morbidity, and social burden. Although reperfusion therapy (thrombolysis, thrombectomy) is the gold standard, its…
- Fundamental determinants of rehabilitation potential in patients with cerebral stroke
Мурадимова Альфия Рашидовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
This article presents a systematic review of the fundamental factors influencing the rehabilitation potential of patients after cerebral stroke. It examines the biological and clinical prerequisites for recovery, modern…
- Interrelation of kimokine biomarker levels with clinical parameters in parkinson's disease and parkinsonism “Plus” syndromes
Гульнара Саттаровна Рахимбаева, Дилшодахон Турдикуловна Акрамова · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
This article analyzes the relationship between monocyte-attracting chemical protein-1 (CCL2) levels and clinical indicators in Parkinson's disease and parkinsonism plus syndromes. Serum protein levels were compared with…
- Genetic markers of thrombophilia as a tool for prediction and risk stratification of cerebrovascular diseases in women
Рахматуллаева Гулнара Кутпитдиновна, Кадырова Азиза Шавкатовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Objective. To evaluate the prognostic significance of genetic markers of thrombophilia in the development of ischemic stroke in women, taking into account age stratification.Materials and Methods. A total of 97 women…
- Relationship of levels with clinical parameters a marker of neuroaxonal damage in parkinson's disease and atypic parkinsonism syndromes
Дилшода Турдикуловна Акрамова · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
This study investigates the relationship between serum neurofilament light chain levels and clinical parameters in patients with Parkinson’s disease and Parkinsonism syndromes. The analysis included motor and cognitive…
- Joint interaction of SOD2, EDN1, and eNOS gene polymorphisms in the development of cerebrovascular diseases
Иноятова Ситора Ойбековна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
The article investigates the role of synergistic interactions between polymorphisms in the genes SOD2 (Ala16Val), EDN1 (Lys197Asn), and eNOS (T786C) in the development of cerebrovascular diseases (CVD). The primary…
- Visual evoked potentials: key to diagnosing demyelinating processes of the optic nerve (literature review and own data)
Адамбаев Зуфар Ибрагимович, Киличев Ибодулла Абдуллаевич, Олмосов Ровшан Шерали угли · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
The article addresses the role of visual evoked potentials (VEPs) in diagnosing demyelinating processes of the optic nerve. The study aims to systematize VEP data, integrate existing evidence with clinical observations…
- Cognitive status of young patients with metabolic syndrome
Гайбиев Акмал Ахматжонович, Бободжонов Шахбоз Абдусодикович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Metabolic syndrome (MS) is a complex of interconnected metabolic disorders, including abdominal obesity, insulin resistance, dyslipidemia, and arterial hypertension. In recent decades, there has been a significant…
- Molecular-neurophysiological interactions in the formation of chronic neuropathic pain syndrome: clinical and diagnostic approaches (literature review)
Хайдарова Дилдора Кадировна, Сафарова Махлиё Шавкат кизи · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Chronic neuropathic pain syndrome is one of the most complex and socially significant problems of modern medicine, affecting 6.9% to 10% of the adult population in developed countries. The pathophysiology of neuropathic…
- Composition (structure) of cognitive impairments in chronic cerebral ischemia
Саноева Матлюба Жахонкуловна, Намозова Хурмат Жалиловна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Purpose. Study of the structure of neuropsychological damage depending on the stages of chronic cerebral ischemia (CCI), analysis of causes and factors. Materials and methods. 172 (100%) patients underwent neurological…
- A new approach to the comprehensive treatment of post-stroke epilepsy
Собирова Донохон Саидаскархановна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Post-stroke epilepsy is one of the most significant complications of stroke, exerting a negative impact on the recovery of cognitive and motor functions as well as on patients’ quality of life. Despite the accumulated…
- Importance of kinesiotherapy and neuromuscular stimulation in the rehabilitation of children
Ахмаджон Абдумаъруф исок угли, Мавлянова Зилола Фархадовна, Ким Ольга Анатольевна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
The aim of the research: development and testing of personalized programs aimed at correcting biomechanical disorders, reducing neurological manifestations and improving the quality of life of patients. Materials and…
- The main etiological factors of congenital sensoneural hearing impairment in children
Олимов Жахонгир Абдуазимжон угли, Абдукаюмов Абдуманноп Абдумаджидович, Мусаев Абдухалил Абдуганиевич, Разаков Азамат Жураевич · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
The article highlights the main etiological factors of congenital sensorineural hearing loss in children and its diagnostic significance in modern otorhinolaryngology. Sensorineural hearing loss at an early age creates…
- The impact of previous infections and andrological pathology on male fertility: a neurological approach to analysis
Маджидова Ёкутхон Набиевна, Рахмонов Исломбек Абдурашид угли, Азимова Нодира Мирваситовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Male infertility is a multifaceted problem that can be caused by various etiopathogenetic factors. Among the most significant causes of infertility are infections and andrological diseases. Infectious diseases of the…
- The results of treatment of primary forms of cerebrovascular diseases with ceruloplasmin and iodine-bromine baths
Рахимкулов Азамат Салаватович, Мавлянова Зилола Фархадовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
The article presents the results of study of efficacy of intranasal electrophoresis with ceruloplasmin and a course of iodinebromine baths in patients with primary forms of cerebrovascular diseases. Application of…
- Assessment of quality of life in patients with acromegaly and secondary empty sella syndrome using the international acro-qol questionnaire
Холикова А.О, Абидова Д.Х · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
The purpose of the study is to evaluate the quality of life of patients with acromegaly and secondary syndrome of the "empty" Turkish saddle using the Acro-Col questionnaire. Material and research methods. On the basis…
- Neuroplasticity and physical activity: compensatory mechanisms in neurodegeneration
Ахунова Тамина Адыл кизи · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
This article discusses how physical exercise can support brain recovery and improve functions in neurodegenerative diseases. The research findings confirm that physical activity increases growth factors in the brain and…
- Non-motor symptoms of parkinson's disease: clinical significance and therapeutic approaches
Пулатова Дилёра Рустамовна, Саидвалиев Фаррух Саидакрамович, Хамидов Абдулахад Абдисаттарович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
A total of 100 patients with Parkinson’s disease at stages I–III according to the Hoehn and Yahr scale, receiving outpatient care, were examined. All patients underwent comprehensive clinical-neurological and…
- Spesific ffeatures of neurological symptoms in patients with subclinical hypoteriosis
Марупов Аброржон Тоштургун угли, Мурадимова Альфия Рашидовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Subclinical hypothyroidism is a widespread endocrine disorder that often remains undiagnosed. The latent course of this condition, especially its manifestation through neurological symptoms, has garnered increasing…
- Functional recovery and rehabilitation potential after removal of intracranial meningiomas
Равшанов Даврон Мавлонович, Мавлянова Зилола Фархадовна, Ашуров Рустамжон Фуркатович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Meningiomas account for 30-35% of primary intracranial tumors in adults and are 1.8-2 times more common in women. Most Grade I tumors grow slowly, but up to 25% of Grade II-III tumors show atypia, deep invasion, and a…
- The relationship between speech disorders in stroke patients and neurological status (based on the nihss and speech therapy scales)
Расулова Муниса Бахтияр қизи · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
This scientific study investigates the relationship between post-stroke speech disorders and the neurological status of patients as a factor influencing speech function. The research was conducted between 2021 and 2024…
- Comprehensive therapy of vertebrobasilar insufficiency using traditional medicine methods (acupuncture)
Мамарасулов Солижон Каюмович, Маджидова Якутхон Набиевна, Эргашева Наргиза Обиджановна, Назарова Салима Каюмовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-06-26
The treatment of vertebrobasilar insufficiency (VBI) remains one of the most urgent problems in modern medicine. VBI—a common form of cerebrovascular disorder—represents a reversible ischemia of brain structures…
- Indicators of neurological status in chronic cerebral ischemia
Маджидова Ёкутхон Набиевна, Низамходжаева Шахзода Бахтиёр қизи, Азимова Нодира Мирваситовна, Ботирова Зебо Хасан қизи · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-06-26
The main pathogenetic factors in the development of chronic cerebral ischemia are atherosclerotic vascular changes and arterial hypertension, which are observed in the overwhelming majority of cases (95–97%). Recent…
- Comprehensive evaluation of diagnostic criteria for carpal tunnel syndrome in middle-aged patients
Хасанов Алишер Юрьевич, Мавлянова Зилола Фархадовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-06-26
The study included 107 patients (60 women and 47 men) aged 35 to 60 years who presented with complaints of paresthesia, pain, and weakness in the hand. All participants underwent clinical tests (Phalen, Tinel, Durkan)…
- Clinical and morphological features of ischemic stroke and risk factors in women of fertile age
Камалова Малика Илҳомовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-06-26
Ишемический инсульт (ИИ) представляет собой одно из наиболее серьезных заболеваний, вызывающих значительную смертность и инвалидизацию населения по всему миру. В последние десятилетия наблюдается рост заболеваемости…
- Distinctive features of clinical and semiological parameters in patients with mesial temporal lobe epilepsy with hippocampal sclerosis
Азизова Раъно Баходировна, Султонова Дилбар Азамат кизи · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-06-26
The study involved 88 participants: the main group consisted of 30 patients diagnosed with MTLE-HS, the comparison group included 36 patients with other types of epilepsy, and the control group comprised 22 healthy…
- Prediction of intraoperative blood loss in the surgery of hypervascular intracranial meningiomas: a radiological risk assessment scale
Эшкувватов Гайрат Эркинович, Кариев Гайрат Маратович, Асадуллаев Улугбек Максудович, Якубов Жахонгир Баходирович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-06-26
This study presents the development of a clinical and radiological risk assessment scale for predicting massive intraoperative blood loss during the surgical removal of hypervascular brain meningiomas. Key risk factors…
- Prospective approaches to rehabilitation of alzheimer's disease
Хайдарова Дилдора Қодировна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-06-26
Alzheimer's disease is a progressive neurodegenerative disorder that affects the brain and leads to deterioration of cognitive functions, memory loss, and changes in personality traits. Given the rapid aging of the…
- Neurological and clinical parameters used to diagnose myasthenia gravis
Ходжиева Дилбар Таджиевна, Шукруллоева Нодирабегим Акбаровна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-06-26
Myasthenia gravis is an autoimmune disease characterized by muscle weakness and fatigue, which increase with physical exertion and decrease at rest. The precise definition and diagnosis of myasthenia gravis is a complex…
- Treatment of cervical-shoulder pain syndrome with local anesthetics: clinical and therapeutic approach
Исаметдинова Умида Зайнитдиновна, Гайбиев Акмалжон Ахмаджонович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-06-26
Cervical-shoulder pain syndrome (CSPS) is one of the most common conditions in applied neurology and general therapeutic practice today, with a complex etiopathogenesis that sharply reduces the patient's motor activity…
Ha. Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research O‘zbekiston Oliy attestatsiya komissiyasi (OAK) ro‘yxatidagi ilmiy jurnal — 361/5-sonli qaror (27 сентябрь 2024), ixtisoslik: 14.00.00 Тиббиёт фанлари.
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