This article analyzes the relationship between monocyte-attracting chemical protein-1 (CCL2) levels and clinical indicators in Parkinson's disease and parkinsonism plus syndromes. Serum protein levels were compared with motor, cognitive, and stage changes. According to the study results, the level of this protein in parkinsonism plus syndromes was significantly higher and correlated significantly with Hoehn & Yahr, UPDRS, and MMSE indicators. These results indicate the possibility of using chemical protein-1, which attracts monocytes, as a useful biomarkers in differential diagnosis, prognosis, and assessment of the severity of the disease.
Мурадимова Альфия Рашидовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
This article presents a systematic review of the fundamental factors influencing the rehabilitation potential of patients after cerebral stroke. It examines the biological and clinical prerequisites for recovery, modern…
Рахматуллаева Гулнара Кутпитдиновна, Кадырова Азиза Шавкатовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Objective. To evaluate the prognostic significance of genetic markers of thrombophilia in the development of ischemic stroke in women, taking into account age stratification.Materials and Methods. A total of 97 women…
Адамбаев Зуфар Ибрагимович, Киличев Ибодулла Абдуллаевич, Сапарбаев Кудрат Исмаилович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
The problem of ischemic stroke remains highly relevant in modern neurology due to its high mortality, morbidity, and social burden. Although reperfusion therapy (thrombolysis, thrombectomy) is the gold standard, its…
Дилшода Турдикуловна Акрамова · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
This study investigates the relationship between serum neurofilament light chain levels and clinical parameters in patients with Parkinson’s disease and Parkinsonism syndromes. The analysis included motor and cognitive…
Абзоиров Кудрат Мусульмонкулович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Neurosyphilis is a form of late syphilis with central nervous system involvement that remains relevant in the era of modern antibiotic therapy. In recent decades, against the background of the HIV epidemic and the…
Иноятова Ситора Ойбековна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
The article investigates the role of synergistic interactions between polymorphisms in the genes SOD2 (Ala16Val), EDN1 (Lys197Asn), and eNOS (T786C) in the development of cerebrovascular diseases (CVD). The primary…
Мирджураев Эльбек Миршавкатович, Адамбаев Зуфар Ибрагимович, Маматханова Чарос Баходировна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Cervical myelopathy (CM) is a progressive neurological disorder caused by spinal cord compression in the cervical spine. The pathophysiology of CM is complex and involves a cascade of events such as spinal cord…
Адамбаев Зуфар Ибрагимович, Киличев Ибодулла Абдуллаевич, Олмосов Ровшан Шерали угли · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
The article addresses the role of visual evoked potentials (VEPs) in diagnosing demyelinating processes of the optic nerve. The study aims to systematize VEP data, integrate existing evidence with clinical observations…
Кудратова Нигора Бурхоновна, Абдуллаева Наргиза Нурмаматовна, Камалова Малика Ильхомовна · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Today, migraine is one of the most common and disabling neurological diseases. Migraine occurs 3 times more often in women than in men and affects 18-25% of women of fertile age. Hormonal changes, especially…
Гайбиев Акмал Ахматжонович, Бободжонов Шахбоз Абдусодикович · Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research · 2025-09-12
Metabolic syndrome (MS) is a complex of interconnected metabolic disorders, including abdominal obesity, insulin resistance, dyslipidemia, and arterial hypertension. In recent decades, there has been a significant…