Preeclampsia (PE) remains one of the leading causes of maternal and perinatal morbidity and mortality. The key mechanism of its pathogenesis is endothelial dysfunction associated with an imbalance between pro- and anti-angiogenic factors. The most studied markers include sFlt-1, PlGF, VEGF, and endothelin-1, whose alterations reflect the degree of vascular impairment. Particular attention is given to the neurological complications of PE, including eclampsia, stroke, posterior reversible encephalopathy syndrome, cognitive and psycho-emotional disorders. Their development is associated with disruption of the blood-brain barrier, vasospasm, and neuronal damage. In recent years, neuronal biomarkers such as GFAP and NfL have been investigated, allowing the detection of glial and axonal injury. A comprehensive assessment of endothelial and neuronal markers opens new perspectives for early diagnosis, prognosis, and personalized management of patients with PE.
| Mualliflar | Рахматуллаева Гулнара Кутбитдиновна, Худаярова Севара Муратбековна |
|---|---|
| Jurnal | Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research |
| Nashriyot | Бухоро давлат тиббиёт институти |
| Nashr sanasi | 2025-10-14 |
| Jild | 6 |
| Son | 6 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| Indeksga qo‘shilgan | 2026-08-26 |
эндотелиальная дисфункция, биомаркеры, неврологические осложнения, endothelial dysfunction, biomarkers, neurological complications, эндотелиал дисфункция, биомаркерлар, неврологик асоратлар
| APA | Рахматуллаева Гулнара Кутбитдиновна, & Худаярова Севара Муратбековна (2025). ENDOTHELIAL AND NEURONAL MARKERS IN THE DIAGNOSIS AND PREDICTION OF PREECLAMPSIA. Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(6). https://tadqiqot.uz/index.php/neurology/article/view/12541 |
|---|---|
| GOST (OAK) | Рахматуллаева Гулнара Кутбитдиновна, Худаярова Севара Муратбековна ENDOTHELIAL AND NEURONAL MARKERS IN THE DIAGNOSIS AND PREDICTION OF PREECLAMPSIA // Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research. – 2025. – T. 6, № 6. |
| MLA | Рахматуллаева Гулнара Кутбитдиновна, and Худаярова Севара Муратбековна. “ENDOTHELIAL AND NEURONAL MARKERS IN THE DIAGNOSIS AND PREDICTION OF PREECLAMPSIA.” Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(6), 2025. https://tadqiqot.uz/index.php/neurology/article/view/12541 |
| Chicago | Рахматуллаева Гулнара Кутбитдиновна, and Худаярова Севара Муратбековна. “ENDOTHELIAL AND NEURONAL MARKERS IN THE DIAGNOSIS AND PREDICTION OF PREECLAMPSIA.” Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(6) (2025). https://tadqiqot.uz/index.php/neurology/article/view/12541 |
| Harvard | Рахматуллаева Гулнара Кутбитдиновна, and Худаярова Севара Муратбековна (2025) ‘ENDOTHELIAL AND NEURONAL MARKERS IN THE DIAGNOSIS AND PREDICTION OF PREECLAMPSIA’, Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research, 6(6). https://tadqiqot.uz/index.php/neurology/article/view/12541 |
| BibTeX | @article{article2025,
title = {ENDOTHELIAL AND NEURONAL MARKERS IN THE DIAGNOSIS AND PREDICTION OF PREECLAMPSIA},
author = {Рахматуллаева Гулнара Кутбитдиновна and Худаярова Севара Муратбековна},
journal = {Журнал неврологии и нейрохирургических исследований / Journal of Neurology and Neurosurgical Research},
year = {2025},
volume = {6},
number = {6},
url = {https://tadqiqot.uz/index.php/neurology/article/view/12541}
} |
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