| Nashriyot | Андижон давлат тиббиёт институти |
|---|---|
| Shahar | Toshkent |
| ISSN | 2992-8958 |
| Nashr davriyligi | quarterly scientific and practical jour |
| Maqolalar soni | 121 |
| OAK holati | Ro‘yxatda |
Diabetes mellitus is an important risk factor for the development of infectious complications, particularly diabetic foot infections, purulent-necrotic soft tissue infections, and sepsis. Hyperglycemia, micro- and…
The scientific article presents methods and technical techniques for choosing surgical tactics for infected pancreatic necrosis (IPN) in patients with diabetes mellitus (DM). Clinical trials were conducted on 188…
Precancerous breast conditions in patients with ovarian dysfunction deserve particular attention because of the close physiological relationship between the reproductive and mammary systems. Impaired ovarian steroid…
Fibrocystic mastopathy developing in the setting of ovarian dysfunction is a heterogeneous hormone-dependent condition whose clinical course is largely determined by disturbances in hypothalamic-pituitary-ovarian…
Despite significant advances in emergency obstetrics and gynecology, urgent nongravid metrorrhagia (UNGM) remains one of the most understudied acute problems, particularly its epidemiological and emergency preventive…
Introduction. Diaphyseal fractures of the humerus, complicated by incorrect selection of osteosynthesis technique, insufficient consideration of clinical risk factors, violation of orthopedic regimen by the patient…
Recent research in sports genomics indicates that genes involved in regulating vascular tone, neurohumoral balance, energy metabolism, and myocardial structure significantly influence the adaptation of the…
Surgical treatment of morbid obesity is recognized as highly effective; however, bariatric procedures may induce profound anatomical and functional changes in the gastrointestinal tract. These alterations can contribute…
The use of fluoride-containing medicinal plants in combination with local, inexpensive raw materials is a promising direction for the development of inexpensive dental prophylaxis. Objective: to describe the plant…
Justification. A hidden penis in children is more often associated with an excess of pubic tissue than with a pathology of the organ itself; however, the quantitative clinical and instrumental characteristics of this…
Currently, HRV holds a central place in sports medicine as an integral indicator of the state of autonomic regulation and adaptive reserves. Time-domain HRV parameters reflect overall variability and the contribution of…
This study evaluated the effect of an early comprehensive rehabilitation program—comprising physical therapy (exercise therapy), a herbal preparation, and magnetotherapy in addition to standard treatment and standard…
During the study of morphological changes in the regional lymph nodes of the pancreas in alcoholic pancreatitis, the following were studied. In particular, the development of subcapsular edema in the lymph nodes, the…
In recent years, among the genes associated with success in sports and adaptation to physical exertion, NOS3 (endothelial nitric oxide synthase gene) has garnered particular attention. Polymorphisms of the NOS3 gene…
The aim of the study was to investigate the effects of experimental chronic carbon monoxide intoxication on the morphological and morphometric characteristics of the frontal cortex of the cerebral hemispheres in 3, 9…
Bariatric surgery provides a substantial and sustained reduction in body weight and contributes to the improvement of obesity-related metabolic disorders. However, anatomical and functional changes in the…
Clinical and epidemiological studies show that bronchial obstruction associated with bronchial asthma and chronic obstructive pulmonary disease is widespread among the population of different ages and that its frequency…
Objective. To identify the clinical, anamnestic and reproductive characteristics of infertile women with autoimmune thyroiditis (AIT). Materials and methods. This comparative observational study included 190 infertile…
Recurrent chronic suppurative otitis media is characterized by a persistent inflammatory process involving the structures of the middle ear, with repeated exacerbations and structural alterations of the mucosa…
Background. Biochemical biomarkers are increasingly important for assessing functional recovery and predicting rehabilitation outcomes after ischemic stroke. Objective. To determine the clinical significance of LDH…
Clinical and epidemiological studies show that bronchial obstruction associated with bronchial asthma and chronic obstructive pulmonary disease is widespread among the population of different ages and that its frequency…
The article analyzes the clinical and pharmacological characteristics of medication use during pregnancy and breastfeeding. Physiological changes occurring in the maternal organism significantly affect drug absorption…
Prediabetes is a potentially reversible disorder of carbohydrate metabolism characterized by elevated blood glucose levels, insulin resistance, and a high risk of progression to type 2 diabetes mellitus. This article…
Pelvic organ prolapse is a common pelvic floor problem for women. Pelvic organ prolapse hurts women’s quality of life, hurts women’s productivity, and hurts women’s reproductive health. In recent years researchers have…
Open tibial fractures are among the most severe musculoskeletal injuries and are associated with a high incidence of infectious complications, delayed bone union, and long-term functional impairment. Therefore…
Type 2 diabetes mellitus is one of the most prevalent chronic diseases and is characterized by a prolonged asymptomatic period during which insulin resistance, disturbances of carbohydrate and lipid metabolism…
Iron deficiency anemia (IDA) is highly prevalent among women of reproductive age because menstrual blood loss, pregnancy, childbirth, dietary insufficiency, and gastrointestinal disorders may coexist. The objective of…
Diabetes mellitus causes metabolic and immunological alterations that increase susceptibility to infections and contribute to their severe course. Persistent hyperglycemia impairs immune cell function, promotes vascular…
Objective: To develop an effective algorithm for selecting the side of donor nephrectomy for living-related kidney transplantation based on angionephroscintigraphy. Methods: Radionuclide renal scintigraphy was performed…
Despite the high effectiveness of bariatric surgery in treating type 2 diabetes mellitus, the mechanisms for achieving stable remission of the disease remain insufficiently studied. Alongside clinical and metabolic…
Relevance. Abortion and gestational diabetes are among the most pressing issues in modern obstetrics and perinatology, significantly impacting women's reproductive health and perinatal outcomes. In recent years, special…
Choledocholithiasis complicating gallstone disease, together with the resulting obstructive jaundice, remains one of the most pressing and challenging problems in hepatobiliary surgery. Surgical interventions performed…
Background. The introduction of hemodialysis has represented a major breakthrough in the management of patients with chronic kidney disease (CKD), significantly prolonging survival and improving the quality of life of…
Introduction. Preparing the acetabulum is one of the most technically challenging stages of total hip arthroplasty. The use of standard instruments does not always ensure the uniform removal of marginal osteophytes and…
Ischemic heart disease is a multifactorial condition in which endothelial dysfunction and genetic predisposition play important roles. The present study assessed the Lys198Asn (G>T) polymorphism of the EDN1 gene, which…
Introduction. Among respiratory diseases, pneumonia occupies an important place in the overall structure of pathology in young children. The unfavorable course of pneumonia is often associated with congenital…
This study evaluated the association between an integrated genetic index based on the TGF-β1 CT+TT and CYP2E1 c1/c2+c2/c2 risk genotypes and the clinical severity and unfavorable course of liver cirrhosis. The study…
This article presents the results of the examination and treatment of 108 patients admitted with recurrent chronic critical lower limb ischemia that developed at various intervals after primary reconstructive vascular…
This study evaluated the association between carriage of the CYP2E1 c2 allele and nutritional risk and quality of life in patients with alcohol-related liver cirrhosis. The analysis included 60 patients: 39 with the…
Background: Rehabilitation after arthroplasty for femoral neck pseudarthrosis differs fundamentally from post-fracture protocols due to pre-existing soft-tissue contractures, muscle atrophy, and systemic osteoporosis…
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders affecting women of reproductive age and is considered a leading cause of infertility. Recent studies have demonstrated that different PCOS…
The study retrospectively analyzed clinical data, medical histories, laboratory-instrumental examination re¬sults and morphological myocardial changes in 80 patients with post-COVID syndrome during 2020–2023. The…
Ischemic heart disease is a multifactorial disease in which endothelial dysfunction and genetic predisposition play a significant role in its development. The aim of the study was to investigate the association of the…
In female patients with RA of reproductive age, changes in estradiol and progesterone levels support systemic inflammation, which is reflected in the hyperexpression of proinflammatory cytokines. Moreover, in the…
Background. Lead is one of the most osteotropic toxicants: up to 90% of the total body burden is deposited within the bone mineral matrix, where it competitively substitutes for Ca2+ in the hydroxyapatite lattice…
Calcium and magnesium concentrations increased stepwise from soft to hard water, while the proportion of calcium-oxalate stones rose from 16.7% to 73.5% (χ²=7.245; p~0.03–0.05). Course intake of local mineral water…
In patients with nasal deformities of various origins, the bony structures of the external nose, nasal septum, anterior nasal spine, nasal cavity airways and paranasal sinuses were evaluated using multislice computed…
The menisci are essential anatomical components of the knee joint, providing biomechanical stability, load distribution, and shock absorption. Meniscal injury is among the most common pathologies in traumatology and…
This study investigated the effects of heparin and low-molecular-weight heparin (Clexane) administered in combination with Contrykal on markers of sterile inflammation during early pregnancy in women without genital…
Introduction. Among respiratory diseases, pneumonia occupies an important place in the overall structure of pathology in young children. The unfavorable course of pneumonia is often associated with congenital…