Biomarkers for predicting heart failure following endovascular correction of cardiointerventional septal defects in children

Обидов М. О., Q.I. Xaydarov, Sh.T. Xasanov, M.М. Choriev, M.Y. Poyonov

Zamonaviy tibbiyot jurnali / Journal of modern medicine · 2026-yil

Annotatsiya

Transcatheter closure of septal heart defects in children has long ceased to be an experimental technique – today it is a routine alternative to open surgery. However, the risk of developing acute and subacute heart failure in the perioperative period remains underestimated, particularly in young children with pre-existing haemodynamic compromise. This study presents the results of a prospective cohort study involving 82 children with septal heart defects, divided into an interventional closure group (n = 52) and an open-heart surgery group with cardiopulmonary bypass (n = 30). The dynamics of NT-proBNP, galectin-3, soluble ST2 and high-sensitivity troponin I were studied in the pre-operative period and over the 7 days following the procedure. It was found that the combination of NT-proBNP and ST2 had the greatest prognostic value with regard to the development of early postoperative heart failure (AUC 0.86; p<0.001). The data obtained support the recommendation that these biomarkers be included in the standard protocol for perioperative monitoring of children undergoing endovascular repair of septal defects.

Maqola ma’lumotlari
MualliflarОбидов М. О., Q.I. Xaydarov, Sh.T. Xasanov, M.М. Choriev, M.Y. Poyonov
JurnalZamonaviy tibbiyot jurnali / Journal of modern medicine
NashriyotАндижон давлат тиббиёт институти
ISSN2992-8958
Nashr sanasi2026-08-07
Jild14
Son3
Betlar586-594
TilIngliz
Ilmiy sohaTibbiyot
DOI10.67519/nshr.ztj.2026.03.020
Indeksga qo‘shilgan2026-09-02

Ilmiy soha

Iqtibos keltirish

APAОбидов М. О., Q.I. Xaydarov, Sh.T. Xasanov, M.М. Choriev, & M.Y. Poyonov (2026). BIOMARKERS FOR PREDICTING HEART FAILURE FOLLOWING ENDOVASCULAR CORRECTION OF CARDIOINTERVENTIONAL SEPTAL DEFECTS IN CHILDREN. Zamonaviy tibbiyot jurnali / Journal of modern medicine, 14(3), 586-594. https://doi.org/10.67519/nshr.ztj.2026.03.020
GOST (OAK)Обидов М. О. va b. BIOMARKERS FOR PREDICTING HEART FAILURE FOLLOWING ENDOVASCULAR CORRECTION OF CARDIOINTERVENTIONAL SEPTAL DEFECTS IN CHILDREN // Zamonaviy tibbiyot jurnali / Journal of modern medicine. – 2026. – T. 14, № 3. – P. 586-594. – DOI: 10.67519/nshr.ztj.2026.03.020.
MLAОбидов М. О., Q.I. Xaydarov, Sh.T. Xasanov, M.М. Choriev, and M.Y. Poyonov. “BIOMARKERS FOR PREDICTING HEART FAILURE FOLLOWING ENDOVASCULAR CORRECTION OF CARDIOINTERVENTIONAL SEPTAL DEFECTS IN CHILDREN.” Zamonaviy tibbiyot jurnali / Journal of modern medicine, 14(3), 586-594, 2026. https://doi.org/10.67519/nshr.ztj.2026.03.020
ChicagoОбидов М. О., Q.I. Xaydarov, Sh.T. Xasanov, M.М. Choriev, and M.Y. Poyonov. “BIOMARKERS FOR PREDICTING HEART FAILURE FOLLOWING ENDOVASCULAR CORRECTION OF CARDIOINTERVENTIONAL SEPTAL DEFECTS IN CHILDREN.” Zamonaviy tibbiyot jurnali / Journal of modern medicine, 14(3), 586-594 (2026). https://doi.org/10.67519/nshr.ztj.2026.03.020
HarvardОбидов М. О., Q.I. Xaydarov, Sh.T. Xasanov, M.М. Choriev, and M.Y. Poyonov (2026) ‘BIOMARKERS FOR PREDICTING HEART FAILURE FOLLOWING ENDOVASCULAR CORRECTION OF CARDIOINTERVENTIONAL SEPTAL DEFECTS IN CHILDREN’, Zamonaviy tibbiyot jurnali / Journal of modern medicine, 14(3), 586-594. https://doi.org/10.67519/nshr.ztj.2026.03.020
BibTeX
@article{article2026,
  title = {BIOMARKERS FOR PREDICTING HEART FAILURE FOLLOWING ENDOVASCULAR CORRECTION OF CARDIOINTERVENTIONAL SEPTAL DEFECTS IN CHILDREN},
  author = {Обидов М. О. and Q.I. Xaydarov and Sh.T. Xasanov and M.М. Choriev and M.Y. Poyonov},
  journal = {Zamonaviy tibbiyot jurnali / Journal of modern medicine},
  year = {2026},
  volume = {14},
  number = {3},
  pages = {586-594},
  doi = {10.67519/nshr.ztj.2026.03.020},
  url = {https://doi.org/10.67519/nshr.ztj.2026.03.020}
}

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