| Nashriyot | Андижон давлат тиббиёт институти |
|---|---|
| Shahar | Toshkent |
| ISSN | 2992-8958 |
| Nashr davriyligi | quarterly scientific and practical jour |
| Maqolalar soni | 121 |
| OAK holati | Ro‘yxatda |
Simultaneous surgical interventions have become an important direction in modern gynecological practice due to their ability to improve treatment outcomes while reducing the physical and psychological burden on…
Irritable bowel syndrome (IBS) is a complex disease manifested by the disruption of intestinal functions and numerous gastroenterological symptoms. The signs of this syndrome are typically associated with…
Thoracic surgery has accumulated significant experience in the use of multimodal analgesia, primarily during planned interventions. The modern approach to anesthetic management предполагает the presence of objective…
For the first time in the Uzbekistan region, allergenic and antigenic properties of an extract from industrial dust of the textile industry have been established. In an experiment on guinea pigs, the criteria of…
Moyamoya disease is a rare chronic cerebrovascular disorder characterized by progressive stenosis or occlusion of the terminal portions of the internal carotid arteries and their major branches, accompanied by the…
Irritable bowel syndrome (IBS) is one of the most common diseases of the internal organs. According to generalized data from population studies worldwide, the prevalence of IBS varies from 10 to 25%. A key link in the…
The urgency of the allergy problem is explained by the increasing number of deaths from severe allergies. Modern man exists in a world of allergens. Allergens are substances of various nature and origin. In this regard…
Background. Fractures of the distal third of the tibia remain among the most challenging injuries in modern orthopedic trauma due to the unique anatomical and biomechanical characteristics of this region, limited blood…
This literature review describes the morphological characteristics of atherosclerotic plaques in the superficial femoral artery, the mechanisms underlying the development of restenosis and reocclusion during the…
Assessment of preoperative clinical and biochemical blood analysis, acid-base balance, and coagulogram parameters in neonates born with esophageal atresia, as well as determination of the baseline homogeneity of the…
Relevance of the topic: The increasing prevalence of kidney diseases and the widespread use of nephrectomy procedures highlight the relevance of research in this field. Unilateral nephrectomy affects not only…
This literature review is devoted to the evaluation of the diagnostic capabilities of magnetic resonance imaging (MRI), particularly MRI combined with cerebral perfusion imaging. Special attention is given to the…
Background. Lead is one of the most osteotropic toxicants: up to 90% of the total body burden is deposited within the bone mineral matrix, where it competitively substitutes for Ca2+ in the hydroxyapatite lattice…
Introduction. Community-acquired pneumonia remains a leading pathology in young children. The diagnosis and treatment of pneumonia in the presence of concomitant congenital heart defects present particular difficulties…
This article examines 115 patients with various forms of hemorrhoidal disease. The short-term results of hemorrhoidectomy using a LOTUS (BOWA MEDIKAL) torsional ultrasonic scalpel with an output frequency of 36 kHz and…
Intrauterine adhesions (Asherman syndrome) are recognized as one of the major causes of secondary infertility, menstrual disorders, and recurrent pregnancy loss. Despite more than seventy years of research into this…
This literature review describes the morphological characteristics of atherosclerotic plaques in the superficial femoral artery, the mechanisms underlying the development of restenosis and reocclusion during the…
Objective: To substantiate and evaluate the clinical efficacy of a three-stage medical rehabilitation programme for patients after decompressive surgery on the lumbosacral spine, based on Mechanical Diagnosis and…
ST-segment elevation myocardial infarction (STEMI) remains one of the leading causes of mortality and disability among patients with cardiovascular diseases. Despite advances in contemporary reperfusion therapy, the…
The aim of this study was to assess renal function disorders in patients with prediabetes using clinical and laboratory methods. The study was conducted at the Andijan Regional Endocrinology Dispensary and included 55…
Chronic heart failure (CHF) developing on the background of ischemic heart disease (IHD) remains one of the leading causes of disability and mortality worldwide. Identification of molecular genetic factors associated…
Traumatic tympanic membrane perforation (TTMP) remains one of the most common causes of acute hearing loss encountered in otorhinolaryngological practice. Mechanical, blast-related, or iatrogenic injury to the tympanic…
Thoracolumbar spinal cord injuries are associated with limited ability to attain an upright position, impaired balance, reduced exercise tolerance, and loss of independent walking. One of the promising approaches in…
The continuous development of minimally invasive technologies has significantly transformed gynecological surgery. Combined minimally invasive surgical interventions enable simultaneous treatment of multiple…
The choice of anesthetic strategy in children undergoing craniotomy for brain tumors requires a comprehensive assessment not only of intracranial hypertension control, but also of systemic hemodynamics, tissue…
To study the clinical and hormonal characteristics and the prevalence of different forms of mastopathy in women with thyroid gland pathology in the Bukhara region, 100 women aged 18–59 years with benign breast diseases…
Dental implantation has become one of the most effective methods for restoring missing teeth and improving patients’ quality of life. However, patients with diabetes mellitus represent a special clinical group due to…
Chronic carbon monoxide exposure results in persistent tissue hypoxia and induces structural alterations in renal tissue, particularly within the glomerular and tubular compartments of the nephron. The present study…
The aim of this study was to evaluate the clinical significance of Bispectral Index (BIS) monitoring for objective assessment of anesthesia depth in children undergoing surgical correction of congenital heart defects…
Chronic carbon monoxide exposure induces persistent tissue hypoxia and leads to structural and functional alterations, particularly in metabolically active organs. The kidney is highly susceptible to oxygen deficiency…
The development and evaluation of novel agents with antipyretic activity remain a priority in experimental pharmacology, particularly with regard to the development of safe and effective therapeutic strategies for the…
Unstable pelvic ring fractures are among the most severe injuries associated with polytrauma and are characterized by high mortality rates. In particular, cases accompanied by intrapelvic hemorrhage remain one of the…
This article presents the long-term results of a study on the dynamics of changes in the total microbial count (TMC) and coliform bacteria (CB) indicators in drinking water across the districts of the Bukhara region…
Transcatheter closure of septal heart defects in children has long ceased to be an experimental technique – today it is a routine alternative to open surgery. However, the risk of developing acute and subacute heart…
A sociological study was conducted to assess nutrition-related knowledge, attitudes toward school meals, and food preferences among students of general education schools. The study was carried out in five general…
This scientific article investigates the diagnostic significance of immunoinflammatory biomarkers, cervical changes, and infectious factors in the early prediction of preterm birth risk in pregnant women. The study…
The present study investigated the effect of maternal diabetes mellitus on the postnatal development of mesenteric lymph nodes (MLNs) in rats. Diabetes was induced in female rats prior to pregnancy by alloxan…
This article investigates the role of lymphocytic infiltration, assessed by the immunohistochemical marker CD45, in the pathogenesis of acute gastric mucosal injury in critically ill patients receiving mechanical…
Background. Polymorphisms of the TCF7L2 gene are among the most important genetic risk factors for type 2 diabetes mellitus (T2DM); however, their role in the development of diabetic kidney disease (DKD) remains…
The experience of combating the COVID-19 pandemic has demonstrated the importance of consistently applying these stages. Certainly, studying the genetic characteristics of the SARS-CoV-2 virus and the large-scale…
This article is devoted to clinical changes in women during premenopause, menopause, and postmenopause. Conditions and diseases that arise in the premenopausal period require early diagnosis and preventive measures…
This scientific article comprehensively analyzes the clinical and functional criteria influencing the development of postcholecystectomy syndrome using sleeve resection as an example. In recent years, along with the…
Cardiac surgery-associated acute kidney injury (CSA-AKI) is a frequent complication of open-heart surgery performed with cardiopulmonary bypass (CPB). The aim was to assess the frequency of, and factors associated with…
This cross-sectional study compared the cardiometabolic profile of age-matched patients with type 2 diabetes mellitus (T2DM) with and without a history of coronary artery stenting (38 vs 20 patients, aged 50–70 years)…
Despite the accumulated evidence regarding the role of hyperprolactinemia (HPRL) in the pathogenesis of breast cancer (BC), the genetic determinants of this condition remain insufficiently investigated. Single…
This literature review analyzes modern approaches to the differential diagnosis of vital (antemortem) and postmortem burns. In forensic medical practice, determining whether burn injuries occurred during life or after…
Cardiac surgery–associated acute kidney injury (CSA-AKI) complicates 20–50% of procedures requiring cardiopulmonary bypass (CPB), independently increasing perioperative mortality threefold to fivefold, triggering…
This article systematizes the molecular and biological mechanisms of tumor immune evasion in cervical cancer associated with high-risk human papillomavirus (HPV) infection and provides a comprehensive review of clinical…
Unstable pelvic ring fractures are among the most severe injuries associated with polytrauma and are characterized by high mortality rates. In particular, cases accompanied by intrapelvic hemorrhage remain one of the…
Echinococcosis of the liver remains one of the most difficult forms of parasitic diseases in surgery, especially in endemic regions where the frequency of postoperative complications remains high. The aim of the study…