Chronic carbon monoxide exposure induces persistent tissue hypoxia, resulting in structural remodeling of the kidney. The severity of renal injury largely depends on age-related adaptive capacity of the nephron. The present study aimed to evaluate age-related morphological alterations of renal tissue following chronic carbon monoxide exposure. The study was carried out on 3- and 9-month-old male albino rats. Histological and morphometric analyses were performed to assess glomerular architecture, Bowman's capsule space, tubular morphology, and interstitial tissue. The results demonstrated that renal alterations in 3-month-old animals were predominantly adaptive, whereas 9-month-old rats exhibited more pronounced glomerular remodeling, widening of Bowman's capsule space, tubular epithelial degeneration, and interstitial expansion. Morphometric analysis confirmed that the severity of hypoxia-induced structural remodeling increased with age.
| Mualliflar | I.A. Mirkhadjaev, I.S. Khamrоev |
|---|---|
| Jurnal | Zamonaviy tibbiyot jurnali / Journal of modern medicine |
| Nashriyot | Андижон давлат тиббиёт институти |
| ISSN | 2992-8958 |
| Nashr sanasi | 2026-07-28 |
| Jild | 14 |
| Son | 3 |
| Betlar | 382-389 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| DOI | 10.67519/nshr.ztj.2026.03.040 |
| Indeksga qo‘shilgan | 2026-09-02 |
DOI: 10.67519/nshr.ztj.2026.03.040 · Maqolaning asl sahifasi · PDF
| APA | I.A. Mirkhadjaev, & I.S. Khamrоev (2026). AGE-RELATED MORPHOLOGICAL REMODELING OF RENAL TISSUE DURING CHRONIC CARBON MONOXIDE EXPOSURE. Zamonaviy tibbiyot jurnali / Journal of modern medicine, 14(3), 382-389. https://doi.org/10.67519/nshr.ztj.2026.03.040 |
|---|---|
| GOST (OAK) | I.A. Mirkhadjaev, I.S. Khamrоev AGE-RELATED MORPHOLOGICAL REMODELING OF RENAL TISSUE DURING CHRONIC CARBON MONOXIDE EXPOSURE // Zamonaviy tibbiyot jurnali / Journal of modern medicine. – 2026. – T. 14, № 3. – P. 382-389. – DOI: 10.67519/nshr.ztj.2026.03.040. |
| MLA | I.A. Mirkhadjaev, and I.S. Khamrоev. “AGE-RELATED MORPHOLOGICAL REMODELING OF RENAL TISSUE DURING CHRONIC CARBON MONOXIDE EXPOSURE.” Zamonaviy tibbiyot jurnali / Journal of modern medicine, 14(3), 382-389, 2026. https://doi.org/10.67519/nshr.ztj.2026.03.040 |
| Chicago | I.A. Mirkhadjaev, and I.S. Khamrоev. “AGE-RELATED MORPHOLOGICAL REMODELING OF RENAL TISSUE DURING CHRONIC CARBON MONOXIDE EXPOSURE.” Zamonaviy tibbiyot jurnali / Journal of modern medicine, 14(3), 382-389 (2026). https://doi.org/10.67519/nshr.ztj.2026.03.040 |
| Harvard | I.A. Mirkhadjaev, and I.S. Khamrоev (2026) ‘AGE-RELATED MORPHOLOGICAL REMODELING OF RENAL TISSUE DURING CHRONIC CARBON MONOXIDE EXPOSURE’, Zamonaviy tibbiyot jurnali / Journal of modern medicine, 14(3), 382-389. https://doi.org/10.67519/nshr.ztj.2026.03.040 |
| BibTeX | @article{iamirkhadjaev2026,
title = {AGE-RELATED MORPHOLOGICAL REMODELING OF RENAL TISSUE DURING CHRONIC CARBON MONOXIDE EXPOSURE},
author = {I.A. Mirkhadjaev and I.S. Khamrоev},
journal = {Zamonaviy tibbiyot jurnali / Journal of modern medicine},
year = {2026},
volume = {14},
number = {3},
pages = {382-389},
doi = {10.67519/nshr.ztj.2026.03.040},
url = {https://doi.org/10.67519/nshr.ztj.2026.03.040}
} |
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