Diabetes mellitus causes metabolic and immunological alterations that increase susceptibility to infections and contribute to their severe course. Persistent hyperglycemia impairs immune cell function, promotes vascular damage, and delays tissue repair. Consequently, infectious foci may persist, spread into deeper tissues, and disseminate through the bloodstream. In patients with diabetes mellitus, sepsis is frequently associated with infected diabetic foot lesions, urinary tract infections, pneumonia, and infections of the skin and soft tissues. This article discusses metabolic, immunological, and hemodynamic factors contributing to the spread of infection, the principal mechanisms of sepsis development, and preventive measures.
| Mualliflar | К. J. Matmurotov, S.S. Xudoyorov, Igor Yakubov, U.G. Voxidov |
|---|---|
| Jurnal | Zamonaviy tibbiyot jurnali / Journal of modern medicine |
| Nashr sanasi | 2026-08-11 |
| Jild | 14 |
| Son | 3 |
| Betlar | 658-662 |
| Til | en |
| DOI | 10.67519/nshr.ztj.2026.03.094 |
DOI: 10.67519/nshr.ztj.2026.03.094 · Maqolaning asl sahifasi · PDF
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