Influence of individualized early rehabilitation on inflammation, endothelial dysfunction, and pulmonary hemodynamic parameters in chronic obstructive pulmonary disease

A. Kh Abdullaev, J.O. Matkomilov

Zamonaviy tibbiyot jurnali / Journal of modern medicine · 2026-yil

Annotatsiya

This study evaluated the effect of an early comprehensive rehabilitation program—comprising physical therapy (exercise therapy), a herbal preparation, and magnetotherapy in addition to standard treatment and standard rehabilitation—on inflammation, endothelial dysfunction, and pulmonary hemodynamics in 127 patients with chronic obstructive pulmonary disease (COPD). The results demonstrated that in the main group, the levels of TNF-α decreased significantly by 43.91–51.58%, VEGF by 49.50–50.46%, and Endothelin-1 by 46.03–47.27% (p<0.001). In addition, echocardiographic evaluation revealed a marked reduction in systolic pulmonary artery pressure (SPAP). These findings confirm the high clinical and pathogenetic efficacy of early comprehensive rehabilitation in reducing chronic inflammation, correcting endothelial dysfunction, and improving pulmonary hemodynamics in COPD patients.

Maqola ma’lumotlari
MualliflarA. Kh Abdullaev, J.O. Matkomilov
JurnalZamonaviy tibbiyot jurnali / Journal of modern medicine
NashriyotАндижон давлат тиббиёт институти
ISSN2992-8958
Nashr sanasi2026-08-21
Jild14
Son3
Betlar765-772
TilIngliz
Ilmiy sohaTibbiyot
DOI10.67519/nshr.ztj.2026.03.112
Indeksga qo‘shilgan2026-09-02

DOI: 10.67519/nshr.ztj.2026.03.112 · Maqolaning asl sahifasi · PDF

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAA. Kh Abdullaev, & J.O. Matkomilov (2026). INFLUENCE OF INDIVIDUALIZED EARLY REHABILITATION ON INFLAMMATION, ENDOTHELIAL DYSFUNCTION, AND PULMONARY HEMODYNAMIC PARAMETERS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE. Zamonaviy tibbiyot jurnali / Journal of modern medicine, 14(3), 765-772. https://doi.org/10.67519/nshr.ztj.2026.03.112
GOST (OAK)A. Kh Abdullaev, J.O. Matkomilov INFLUENCE OF INDIVIDUALIZED EARLY REHABILITATION ON INFLAMMATION, ENDOTHELIAL DYSFUNCTION, AND PULMONARY HEMODYNAMIC PARAMETERS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE // Zamonaviy tibbiyot jurnali / Journal of modern medicine. – 2026. – T. 14, № 3. – P. 765-772. – DOI: 10.67519/nshr.ztj.2026.03.112.
MLAA. Kh Abdullaev, and J.O. Matkomilov. “INFLUENCE OF INDIVIDUALIZED EARLY REHABILITATION ON INFLAMMATION, ENDOTHELIAL DYSFUNCTION, AND PULMONARY HEMODYNAMIC PARAMETERS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE.” Zamonaviy tibbiyot jurnali / Journal of modern medicine, 14(3), 765-772, 2026. https://doi.org/10.67519/nshr.ztj.2026.03.112
ChicagoA. Kh Abdullaev, and J.O. Matkomilov. “INFLUENCE OF INDIVIDUALIZED EARLY REHABILITATION ON INFLAMMATION, ENDOTHELIAL DYSFUNCTION, AND PULMONARY HEMODYNAMIC PARAMETERS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE.” Zamonaviy tibbiyot jurnali / Journal of modern medicine, 14(3), 765-772 (2026). https://doi.org/10.67519/nshr.ztj.2026.03.112
HarvardA. Kh Abdullaev, and J.O. Matkomilov (2026) ‘INFLUENCE OF INDIVIDUALIZED EARLY REHABILITATION ON INFLAMMATION, ENDOTHELIAL DYSFUNCTION, AND PULMONARY HEMODYNAMIC PARAMETERS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE’, Zamonaviy tibbiyot jurnali / Journal of modern medicine, 14(3), 765-772. https://doi.org/10.67519/nshr.ztj.2026.03.112
BibTeX
@article{akhabdullaev2026,
  title = {INFLUENCE OF INDIVIDUALIZED EARLY REHABILITATION ON INFLAMMATION, ENDOTHELIAL DYSFUNCTION, AND PULMONARY HEMODYNAMIC PARAMETERS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE},
  author = {A. Kh Abdullaev and J.O. Matkomilov},
  journal = {Zamonaviy tibbiyot jurnali / Journal of modern medicine},
  year = {2026},
  volume = {14},
  number = {3},
  pages = {765-772},
  doi = {10.67519/nshr.ztj.2026.03.112},
  url = {https://doi.org/10.67519/nshr.ztj.2026.03.112}
}

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