BACKGROUND: The consumption of chocolate and cocoa has established cardiovascular benefits. Less is known about the effects of chocolate on arterial stiffness, a marker of subclinical cardiovascular disease. The aim of this study was to investigate whether chocolate intakes are independently associated with pulse wave velocity (PWV), after adjustment for cardiovascular, lifestyle and dietary factors. METHODS: Prospective analyses were undertaken on 508 community-dwelling participants (mean age 61 years, 60% women) from the Maine-Syracuse Longitudinal Study (MSLS). Habitual chocolate intakes, measured using a food frequency questionnaire, were related to PWV, measured approximately 5 years later. RESULTS: Chocolate intake was significantly associated with PWV in a non-linear fashion with the highest levels of PWV in those who never or rarely ate chocolate and lowest levels in those who consumed chocolate once a week. This pattern of results remained and was not attenuated after multivariate adjustment for diabetes, cardiovascular risk factors and dietary variables (p = 0.002). CONCLUSIONS: Weekly chocolate intake may be of benefit to arterial stiffness. Further studies are needed to explore the underlying mechanisms that may mediate the observed effects of habitual chocolate consumption on arterial stiffness.
| Mualliflar | Georgina E. Crichton, Merrill F. Elias, Ala’a Alkerwi, Saverio Stranges, Walter P. Abhayaratna |
|---|---|
| Jurnal | PULSE |
| Nashr sanasi | 2016-01-01 |
| Jild | 4 |
| Son | 1 |
| Betlar | 28-37 |
| Til | en |
| DOI | 10.1159/000445876 |
DOI: 10.1159/000445876 · Maqolaning asl sahifasi
Introduction: Chronic kidney disease (CKD) raises cardiovascular risk, but its link with the cardio-ankle vascular index (CAVI) in diabetic and non-diabetic patients remains unclear. The aim of this study was to clarify…
Cardiovascular disease (CVD) is an important cause of morbidity and mortality in dialysis patients. Brachial-ankle pulse wave velocity (baPWV) is more efficient to handily assess arteriosclerosis than aortic PWV. The…
Introduction: The pulse wave analysis technology in the specialist SphygmoCor XCEL device has now been implemented in the CONNEQT Pulse device, which is a conventional sphygmomanometer suitable for home blood pressure…
Background: Sarcomatoid carcinoma of the urinary bladder is very rare variety of transitional cell carcinoma (TCC) with a prominent component of spindle-shaped cell. The incidence rate of this tumor is 0.5 % of all…
Background: Magnesium (Mg++) deficiency is related with terrible glycemic control. Supplementation of Mg++ lowers blood sugar, improves insulin sensitivity and as a end result, diabetic complications inclusive of…
The cardiopulmonary exercise test (CPET) provides integrative exercise responses including the cardiovascular, pulmonary and skeletal muscle systems. It can be used for the identification of myocardial ischemia…
Introduction: Cardio-ankle vascular index (CAVI), a blood pressure-independent measure of heart-ankle pulse wave velocity, is a relatively new indicator of arterial stiffness. The absolute value of the difference in…
Measuring arterial blood gas is routinely performed in critically ill patients, and may unravel severe life-threatening acid-base disorders or hypoxemia. It provides the vital information about ventilation, oxygenation…
Introduction: Aortic stiffness, assessed through carotid-femoral pulse wave velocity (PWV), has been associated with an increased risk of cardiovascular events and mortality. Measurements of PWV are based on the proper…
Background: Persistent elevation of serum ALP is frequently encountered and can pose a diagnostic dilemma due to its association with a wide range of clinical conditions. However, the significance of ALP in these…