Background: Persistent elevation of serum ALP is frequently encountered and can pose a diagnostic dilemma due to its association with a wide range of clinical conditions. However, the significance of ALP in these clinical conditions in routine practice is often underestimated or overrated. Objectives: This study was determined to assess the pattern of ALP with an aim to elucidate its clinical utility among hospitalized patients. Method & materials: The inpatients with high ALP level were enlisted & analysed between January to December 2012 excluding cases of (a) patients who have bone involvements with malignancies and (b) HIV-seropositive patients attending a tertiary care Hospital at Dhaka. Extremely high levels of ALP were defined as being more than 1000 U/L. These patients were divided into different groups according to their final diagnosis. Results: A total of 154 hospitalized patients with eligible medical records were identified (98 male and 56 female, mean age 36 years). Their ALP levels are ranging from 1,006 to 3,067 IU/L; very extreme values of > 3000 IU/L being rarely (only about 2%) documented. Patients with sepsis can have an extremely high alkaline phosphatase level (1,648.2 ± 328.4 IU/L) and a normal bilirubin. Conclusion: High serum ALP levels in hospitalized patients were commonly found in three major groups having obstructive biliary diseases, infiltrative liver disease and sepsis. A variety of other causes were also noted. This routine laboratory test should receive more attention in clinical decision-making than has previously been given. DOI: http://dx.doi.org/10.3329/pulse.v6i1-2.20329 Pulse Vol.6 January-December 2013 p.20-26
| Mualliflar | Waheeda Nargis, BU Ahamed, Md. Tanbir Hossain, SM Biswas, M Ibrahim |
|---|---|
| Jurnal | PULSE |
| Nashriyot | PROFI университетининг |
| ISSN | 2074-1855, 2235-8668 |
| Nashr sanasi | 2014-09-04 |
| Jild | 6 |
| Son | 1-2 |
| Betlar | 20-26 |
| Til | Ingliz |
| Ilmiy soha | Psixologiya |
| DOI | 10.3329/pulse.v6i1-2.20329 |
| Indeksga qo‘shilgan | 2026-09-02 |
DOI: 10.3329/pulse.v6i1-2.20329 · Maqolaning asl sahifasi · PDF
| APA | Waheeda Nargis, BU Ahamed, Md. Tanbir Hossain, SM Biswas, & M Ibrahim (2014). Pattern of Elevated Serum Alkaline Phosphatase (ALP) Levels in Hospitalized Patients: A Single Centre Study. PULSE, 6(1-2), 20-26. https://doi.org/10.3329/pulse.v6i1-2.20329 |
|---|---|
| GOST (OAK) | Waheeda Nargis va b. Pattern of Elevated Serum Alkaline Phosphatase (ALP) Levels in Hospitalized Patients: A Single Centre Study // PULSE. – 2014. – T. 6, № 1-2. – P. 20-26. – DOI: 10.3329/pulse.v6i1-2.20329. |
| MLA | Waheeda Nargis, BU Ahamed, Md. Tanbir Hossain, SM Biswas, and M Ibrahim. “Pattern of Elevated Serum Alkaline Phosphatase (ALP) Levels in Hospitalized Patients: A Single Centre Study.” PULSE, 6(1-2), 20-26, 2014. https://doi.org/10.3329/pulse.v6i1-2.20329 |
| Chicago | Waheeda Nargis, BU Ahamed, Md. Tanbir Hossain, SM Biswas, and M Ibrahim. “Pattern of Elevated Serum Alkaline Phosphatase (ALP) Levels in Hospitalized Patients: A Single Centre Study.” PULSE, 6(1-2), 20-26 (2014). https://doi.org/10.3329/pulse.v6i1-2.20329 |
| Harvard | Waheeda Nargis, BU Ahamed, Md. Tanbir Hossain, SM Biswas, and M Ibrahim (2014) ‘Pattern of Elevated Serum Alkaline Phosphatase (ALP) Levels in Hospitalized Patients: A Single Centre Study’, PULSE, 6(1-2), 20-26. https://doi.org/10.3329/pulse.v6i1-2.20329 |
| BibTeX | @article{waheedanargis2014,
title = {Pattern of Elevated Serum Alkaline Phosphatase (ALP) Levels in Hospitalized Patients: A Single Centre Study},
author = {Waheeda Nargis and BU Ahamed and Md. Tanbir Hossain and SM Biswas and M Ibrahim},
journal = {PULSE},
year = {2014},
volume = {6},
number = {1-2},
pages = {20-26},
doi = {10.3329/pulse.v6i1-2.20329},
url = {https://doi.org/10.3329/pulse.v6i1-2.20329}
} |
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