Arterial Stiffening and Clinical Outcomes in Dialysis Patients

Akihiko Kato

PULSE · 2015-yil

Annotatsiya

Cardiovascular disease (CVD) is an important cause of morbidity and mortality in dialysis patients. Brachial-ankle pulse wave velocity (baPWV) is more efficient to handily assess arteriosclerosis than aortic PWV. The cardio-ankle vascular index (CAVI) is also a novel blood pressure-independent arterial stiffness parameter. In dialysis patients, both baPWV and CAVI are increased compared to general subjects. Several studies have demonstrated that increased baPWV is associated with carotid atherosclerosis and diastolic left ventricular dysfunction in hemodialysis (HD) patients. In addition, higher baPWV is related to all-cause and cardiovascular (CV) mortality. CAVI is similarly associated with CVD. However, baPWV is superior to CAVI as a predictor of CV outcomes in HD patients. Besides these outcomes, a close relationship exists between sarcopenia, abdominal visceral obesity and arterial stiffening. Reduction of thigh muscle mass is inversely correlated with baPWV and CAVI in males. Abdominal fatness is also associated with increased arterial stiffness in females. These observations provide further evidence of higher risk of CV events in HD patients with sarcopenic obesity. In addition, arterial stiffness is associated with cerebral small vessel disease and decreased cognitive function in the elderly. However, it is unknown whether arterial stiffness may be useful as an early indicator of cognitive decline in dialysis patients. Because dialysis patients are at risk of developing dementia, more studies are needed to elucidate the causal link between arterial stiffness and cognitive impairment.

Maqola ma’lumotlari
MualliflarAkihiko Kato
JurnalPULSE
NashriyotPROFI университетининг
ISSN2074-1855, 2235-8668
Nashr sanasi2015-01-01
Jild3
Son2
Betlar89-97
TilIngliz
Ilmiy sohaPsixologiya
DOI10.1159/000381927
Indeksga qo‘shilgan2026-09-02

DOI: 10.1159/000381927 · Maqolaning asl sahifasi · PDF

Ilmiy soha

Psixologiya

Iqtibos keltirish

APAAkihiko Kato (2015). Arterial Stiffening and Clinical Outcomes in Dialysis Patients. PULSE, 3(2), 89-97. https://doi.org/10.1159/000381927
GOST (OAK)Akihiko Kato Arterial Stiffening and Clinical Outcomes in Dialysis Patients // PULSE. – 2015. – T. 3, № 2. – P. 89-97. – DOI: 10.1159/000381927.
MLAAkihiko Kato. “Arterial Stiffening and Clinical Outcomes in Dialysis Patients.” PULSE, 3(2), 89-97, 2015. https://doi.org/10.1159/000381927
ChicagoAkihiko Kato. “Arterial Stiffening and Clinical Outcomes in Dialysis Patients.” PULSE, 3(2), 89-97 (2015). https://doi.org/10.1159/000381927
HarvardAkihiko Kato (2015) ‘Arterial Stiffening and Clinical Outcomes in Dialysis Patients’, PULSE, 3(2), 89-97. https://doi.org/10.1159/000381927
BibTeX
@article{akihikokato2015,
  title = {Arterial Stiffening and Clinical Outcomes in Dialysis Patients},
  author = {Akihiko Kato},
  journal = {PULSE},
  year = {2015},
  volume = {3},
  number = {2},
  pages = {89-97},
  doi = {10.1159/000381927},
  url = {https://doi.org/10.1159/000381927}
}

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