In recent years, photodynamic therapy (PDT) has become an effective and minimally invasiveapproach for treating cancer and infectious diseases. However, conventional photosensitizers(PS) are limited by short absorption wavelengths, poor tissue penetration, and phototoxicity.This study addresses these challenges through the use of next-generation PSs, including porphyrins,chlorins, phthalocyanines, methylene blue, and their derivatives. Photoactive naturalcompounds such as hypericin, curcumin, and furocoumarins (psoralen, bergapten) were analyzedfor their low toxicity and high bioactivity. The potential of nanomaterials (liposomes,gold and graphene nanoparticles) as targeted delivery systems for PSs is also discussed. Theresults demonstrate that nano-based PSs can enhance PDT efficiency, reduce phototoxicity,and mitigate tissue hypoxia.
| Mualliflar | Захидов, Э.А., Имомов, М.Х., Нематов, Ш.К., Таджибаев, И.И. |
|---|---|
| Jurnal | O‘zbekiston fizika jurnali |
| Nashriyot | Ўзбекистон Республикаси Фанлар академияси |
| ISSN | 1025-8817, 2181-077X |
| Nashr sanasi | 2026-02-18 |
| Jild | 27 |
| Son | 4 |
| Til | Ingliz |
| Ilmiy soha | Fizika-matematika |
| DOI | 10.52304/.v27i4.618 |
| Indeksga qo‘shilgan | 2026-08-26 |
DOI: 10.52304/.v27i4.618 · Maqolaning asl sahifasi
фотодинамическая терапия, фотосенсибилизатор, синглетный кислород, photodynamic therapy, photosensitizer, singlet oxygen
| APA | Захидов, Э.А., Имомов, М.Х., Нематов, Ш.К., & Таджибаев, И.И. (2026). Highly effective photosensitizers for photodynamic therapy. O‘zbekiston fizika jurnali, 27(4). https://doi.org/10.52304/.v27i4.618 |
|---|---|
| GOST (OAK) | Захидов, Э.А. va b. Highly effective photosensitizers for photodynamic therapy // O‘zbekiston fizika jurnali. – 2026. – T. 27, № 4. – DOI: 10.52304/.v27i4.618. |
| MLA | Захидов, Э.А., Имомов, М.Х., Нематов, Ш.К., and Таджибаев, И.И. “Highly effective photosensitizers for photodynamic therapy.” O‘zbekiston fizika jurnali, 27(4), 2026. https://doi.org/10.52304/.v27i4.618 |
| Chicago | Захидов, Э.А., Имомов, М.Х., Нематов, Ш.К., and Таджибаев, И.И. “Highly effective photosensitizers for photodynamic therapy.” O‘zbekiston fizika jurnali, 27(4) (2026). https://doi.org/10.52304/.v27i4.618 |
| Harvard | Захидов, Э.А., Имомов, М.Х., Нематов, Ш.К., and Таджибаев, И.И (2026) ‘Highly effective photosensitizers for photodynamic therapy’, O‘zbekiston fizika jurnali, 27(4). https://doi.org/10.52304/.v27i4.618 |
| BibTeX | @article{article2026,
title = {Highly effective photosensitizers for photodynamic therapy},
author = {Захидов, Э.А. and Имомов, М.Х. and Нематов, Ш.К. and Таджибаев, И.И.},
journal = {O‘zbekiston fizika jurnali},
year = {2026},
volume = {27},
number = {4},
doi = {10.52304/.v27i4.618},
url = {https://doi.org/10.52304/.v27i4.618}
} |
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