Nephroblastoma in children: treatment structure and clinical outcome analysis

Mustafayev Tojiddin Qurbonovich

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2025-yil

Annotatsiya

Relevance. Nephroblastoma is one of the most common malignant tumors in children. Analyzing therapeutic approaches and complications contributes to improving the quality of treatment. Objective. To assess treatment structure, disease stage, and complication rates in children with nephroblastoma. Materials and Methods. Data from 91 children with histologically confirmed nephroblastoma treated at the Republican Specialized Scientific-Practical Medical Center of Oncology and Radiology (2015–2022) were analyzed. Parameters included clinical staging, treatment modalities, chemotherapy protocols, number of courses, and complications. Descriptive statistics and χ² analysis were applied. Results. 66% of patients were under 3 years of age. The most frequently diagnosed stages were 2B and 3A. Combined treatment was administered in 69.2% of cases, primarily using HT+S+HT and S+HT regimens. The most common chemotherapy scheme was CyVADIC. Complication rates increased with multi-stage treatment approaches. Conclusion. Combined therapy is most effective in intermediate stages of nephroblastoma but requires close monitoring for toxicity. Early diagnosis and treatment individualization are critical for improving outcomes.

Maqola ma’lumotlari
MualliflarMustafayev Tojiddin Qurbonovich
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2025-11-01
Jild10
Son4
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

нефробластома, дети, лечение, химиотерапия, осложнения, стадия опухоли, nephroblastoma, children, treatment, chemotherapy, complications, tumor stage, nefroblastoma, bolalar, davolash, kimyoterapiya, asoratlar, o‘sma bosqichi

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAMustafayev Tojiddin Qurbonovich (2025). NEPHROBLASTOMA IN CHILDREN: TREATMENT STRUCTURE AND CLINICAL OUTCOME ANALYSIS. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(4). https://tadqiqot.uz/index.php/biomedicine/article/view/12692
GOST (OAK)Mustafayev Tojiddin Qurbonovich NEPHROBLASTOMA IN CHILDREN: TREATMENT STRUCTURE AND CLINICAL OUTCOME ANALYSIS // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2025. – T. 10, № 4.
MLAMustafayev Tojiddin Qurbonovich. “NEPHROBLASTOMA IN CHILDREN: TREATMENT STRUCTURE AND CLINICAL OUTCOME ANALYSIS.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(4), 2025. https://tadqiqot.uz/index.php/biomedicine/article/view/12692
ChicagoMustafayev Tojiddin Qurbonovich. “NEPHROBLASTOMA IN CHILDREN: TREATMENT STRUCTURE AND CLINICAL OUTCOME ANALYSIS.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(4) (2025). https://tadqiqot.uz/index.php/biomedicine/article/view/12692
HarvardMustafayev Tojiddin Qurbonovich (2025) ‘NEPHROBLASTOMA IN CHILDREN: TREATMENT STRUCTURE AND CLINICAL OUTCOME ANALYSIS’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(4). https://tadqiqot.uz/index.php/biomedicine/article/view/12692
BibTeX
@article{mustafayevtojiddinqurbonovich2025,
  title = {NEPHROBLASTOMA IN CHILDREN: TREATMENT STRUCTURE AND CLINICAL OUTCOME ANALYSIS},
  author = {Mustafayev Tojiddin Qurbonovich},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2025},
  volume = {10},
  number = {4},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/12692}
}

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