Morphological and immunohistochemical methods in verification of non-muscle invasive bladder cancer

ALLAZOV Iskandar Sallakh ugli, ALLAZOV Sallakh Allazovich, ALLAZOV Feruz Niyazovich, MADALIMOV Akhror Alievich

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2025-yil

Annotatsiya

The article provides a comprehensive review of contemporary diagnostic approaches in bladder cancer (BC) verification, focusing on morphological and immunohistochemical (IHC) methods over the past 5-7 years. The research synthesizes current strategies for molecular subtyping and prognostic assessment of non-muscle invasive bladder cancer (NMIBC). The study analyzes key IHC markers (GATA3, CK7, CK20, Ki-67, p53, p16, Uroplakin III) that enable precise tumor characterization and molecular profiling. Special attention is given to the diagnostic potential of proliferative markers and their correlation with tumor aggressiveness, progression risk, and clinical outcomes. The authors emphasize the critical role of integrated morphological and IHC approaches in improving diagnostic accuracy, patient stratification, and personalized treatment selection. The research highlights the importance of comprehensive marker panels in identifying molecular subtypes and predicting disease progression, particularly in NMIBC. Key findings demonstrate that advanced IHC techniques provide crucial insights into tumor biology, enabling more targeted therapeutic strategies and improving patient management. The study concludes by underlining the need for standardized diagnostic protocols and continued research in molecular oncology.

Maqola ma’lumotlari
MualliflarALLAZOV Iskandar Sallakh ugli, ALLAZOV Sallakh Allazovich, ALLAZOV Feruz Niyazovich, MADALIMOV Akhror Alievich
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2025-10-31
Jild10
Son4
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

рак мочевого пузыря, морфология, ИГХ, методы диагностики, bladder cancer, morphology, immunohistochemically, diagnostic approaches, қовуқ саратони, морфология, ИГХ, диагностик текширув

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAALLAZOV Iskandar Sallakh ugli, ALLAZOV Sallakh Allazovich, ALLAZOV Feruz Niyazovich, & MADALIMOV Akhror Alievich (2025). MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL METHODS IN VERIFICATION OF NON-MUSCLE INVASIVE BLADDER CANCER. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(4). https://tadqiqot.uz/index.php/biomedicine/article/view/12689
GOST (OAK)ALLAZOV Iskandar Sallakh ugli va b. MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL METHODS IN VERIFICATION OF NON-MUSCLE INVASIVE BLADDER CANCER // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2025. – T. 10, № 4.
MLAALLAZOV Iskandar Sallakh ugli, ALLAZOV Sallakh Allazovich, ALLAZOV Feruz Niyazovich, and MADALIMOV Akhror Alievich. “MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL METHODS IN VERIFICATION OF NON-MUSCLE INVASIVE BLADDER CANCER.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(4), 2025. https://tadqiqot.uz/index.php/biomedicine/article/view/12689
ChicagoALLAZOV Iskandar Sallakh ugli, ALLAZOV Sallakh Allazovich, ALLAZOV Feruz Niyazovich, and MADALIMOV Akhror Alievich. “MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL METHODS IN VERIFICATION OF NON-MUSCLE INVASIVE BLADDER CANCER.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(4) (2025). https://tadqiqot.uz/index.php/biomedicine/article/view/12689
HarvardALLAZOV Iskandar Sallakh ugli, ALLAZOV Sallakh Allazovich, ALLAZOV Feruz Niyazovich, and MADALIMOV Akhror Alievich (2025) ‘MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL METHODS IN VERIFICATION OF NON-MUSCLE INVASIVE BLADDER CANCER’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(4). https://tadqiqot.uz/index.php/biomedicine/article/view/12689
BibTeX
@article{allazoviskandarsallakhugli2025,
  title = {MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL METHODS IN VERIFICATION OF NON-MUSCLE INVASIVE BLADDER CANCER},
  author = {ALLAZOV Iskandar Sallakh ugli and ALLAZOV Sallakh Allazovich and ALLAZOV Feruz Niyazovich and MADALIMOV Akhror Alievich},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2025},
  volume = {10},
  number = {4},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/12689}
}

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