Esophageal cancer: the role of preoperative chemotherapy in combination treatment

YUSUPBEKOV Abrorjon Аhmadjanovich, DJURAYEV Murjalol Dehqonovich, DJUMANAZAROV Temirbek Matchanovich, RASULOV Abdugaffor Elmanovich, RAKHIMOV Okiljon Abdukhalilovich

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2025-yil

Annotatsiya

The article presents the results of the efficacy of neoadjuvant chemotherapy in patients with thoracic esophageal cancer. The study analyzes treatment outcomes in 37 patients with stage II–IV disease. All patients received neoadjuvant induction chemotherapy ranging from 2 to 6 cycles using various regimens, including paclitaxel + carboplatin (TC), PF, DCF, and FLOT. In several cases, chemoradiotherapy was administered, combining systemic chemotherapy with subsequent radiotherapy (total dose 40–60 Gy). It was found that neoadjuvant chemotherapy can achieve significant tumor regression. Moreover, the combination of neoadjuvant chemotherapy, chemoradiotherapy, and subsequent surgical treatment in patients with locally advanced thoracic esophageal cancer may improve oncological outcomes.

Maqola ma’lumotlari
MualliflarYUSUPBEKOV Abrorjon Аhmadjanovich, DJURAYEV Murjalol Dehqonovich, DJUMANAZAROV Temirbek Matchanovich, RASULOV Abdugaffor Elmanovich, RAKHIMOV Okiljon Abdukhalilovich
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2025-11-01
Jild10
Son4
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

рак пищевода, химиотерапия, лечебный патоморфоз, esophageal cancer, chemotherapy, therapeutic pathomorphosis, qizilo`ngach saratoni, kimyoterapiya, davo patomorfozi

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAYUSUPBEKOV Abrorjon Аhmadjanovich, DJURAYEV Murjalol Dehqonovich, DJUMANAZAROV Temirbek Matchanovich, RASULOV Abdugaffor Elmanovich, & RAKHIMOV Okiljon Abdukhalilovich (2025). ESOPHAGEAL CANCER: THE ROLE OF PREOPERATIVE CHEMOTHERAPY IN COMBINATION TREATMENT. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(4). https://tadqiqot.uz/index.php/biomedicine/article/view/12696
GOST (OAK)YUSUPBEKOV Abrorjon Аhmadjanovich va b. ESOPHAGEAL CANCER: THE ROLE OF PREOPERATIVE CHEMOTHERAPY IN COMBINATION TREATMENT // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2025. – T. 10, № 4.
MLAYUSUPBEKOV Abrorjon Аhmadjanovich, DJURAYEV Murjalol Dehqonovich, DJUMANAZAROV Temirbek Matchanovich, RASULOV Abdugaffor Elmanovich, and RAKHIMOV Okiljon Abdukhalilovich. “ESOPHAGEAL CANCER: THE ROLE OF PREOPERATIVE CHEMOTHERAPY IN COMBINATION TREATMENT.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(4), 2025. https://tadqiqot.uz/index.php/biomedicine/article/view/12696
ChicagoYUSUPBEKOV Abrorjon Аhmadjanovich, DJURAYEV Murjalol Dehqonovich, DJUMANAZAROV Temirbek Matchanovich, RASULOV Abdugaffor Elmanovich, and RAKHIMOV Okiljon Abdukhalilovich. “ESOPHAGEAL CANCER: THE ROLE OF PREOPERATIVE CHEMOTHERAPY IN COMBINATION TREATMENT.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(4) (2025). https://tadqiqot.uz/index.php/biomedicine/article/view/12696
HarvardYUSUPBEKOV Abrorjon Аhmadjanovich, DJURAYEV Murjalol Dehqonovich, DJUMANAZAROV Temirbek Matchanovich, RASULOV Abdugaffor Elmanovich, and RAKHIMOV Okiljon Abdukhalilovich (2025) ‘ESOPHAGEAL CANCER: THE ROLE OF PREOPERATIVE CHEMOTHERAPY IN COMBINATION TREATMENT’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(4). https://tadqiqot.uz/index.php/biomedicine/article/view/12696
BibTeX
@article{yusupbekovabrorjonhmadjanovich2025,
  title = {ESOPHAGEAL CANCER: THE ROLE OF PREOPERATIVE CHEMOTHERAPY IN COMBINATION TREATMENT},
  author = {YUSUPBEKOV Abrorjon Аhmadjanovich and DJURAYEV Murjalol Dehqonovich and DJUMANAZAROV Temirbek Matchanovich and RASULOV Abdugaffor Elmanovich and RAKHIMOV Okiljon Abdukhalilovich},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2025},
  volume = {10},
  number = {4},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/12696}
}

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