The article presents the results of the efficacy of neoadjuvant chemotherapy in patients with thoracic esophageal cancer. The study analyzes treatment outcomes in 37 patients with stage II–IV disease. All patients received neoadjuvant induction chemotherapy ranging from 2 to 6 cycles using various regimens, including paclitaxel + carboplatin (TC), PF, DCF, and FLOT. In several cases, chemoradiotherapy was administered, combining systemic chemotherapy with subsequent radiotherapy (total dose 40–60 Gy). It was found that neoadjuvant chemotherapy can achieve significant tumor regression. Moreover, the combination of neoadjuvant chemotherapy, chemoradiotherapy, and subsequent surgical treatment in patients with locally advanced thoracic esophageal cancer may improve oncological outcomes.
| Mualliflar | YUSUPBEKOV Abrorjon Аhmadjanovich, DJURAYEV Murjalol Dehqonovich, DJUMANAZAROV Temirbek Matchanovich, RASULOV Abdugaffor Elmanovich, RAKHIMOV Okiljon Abdukhalilovich |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashr sanasi | 2025-11-01 |
| Jild | 10 |
| Son | 4 |
| Til | Rus |
рак пищевода, химиотерапия, лечебный патоморфоз, esophageal cancer, chemotherapy, therapeutic pathomorphosis, qizilo`ngach saratoni, kimyoterapiya, davo patomorfozi
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