This study evaluated the association between carriage of the CYP2E1 c2 allele, nutritional risk, and quality of life in patients with alcohol-related liver cirrhosis. The analysis included 60 patients: 39 with the c1/c1 genotype and 21 carriers of the c1/c2 and c2/c2 genotypes. c2 carriers had significantly lower body mass index and mid-arm circumference, as well as higher NRS-2002 scores. Nutritional deficiency was identified in 90.5% of c2 carriers compared with 59.0% of patients with the c1/c1 genotype, yielding an odds ratio of 6.61. The SF-36 physical and mental component scores were lower by 10.8 and 11.4 points, respectively, among c2 carriers. c2 carriage correlated positively with NRS-2002 and MELD/MELD-Na scores and negatively with serum albumin and the SF-36 physical component score. These findings support early nutritional screening and systematic quality-of-life assessment in c2 carriers with alcohol-related liver cirrhosis.
| Mualliflar | Жасурбек Равзатов, Dildora Nabieva |
|---|---|
| Jurnal | Ўзбекистон метрологияси |
| Nashriyot | Ўзбекистон техник жиҳатдан тартибга солиш агентлиги |
| ISSN | 2181-3663 |
| Nashr sanasi | 2026-04-05 |
| Jild | 5 |
| Son | 2 |
| Betlar | 844-852 |
| Til | Rus |
| Ilmiy soha | Texnika |
| DOI | 10.47689/2181-3663-vol5-iss2-pp844-852 |
| Indeksga qo‘shilgan | 2026-09-02 |
DOI: 10.47689/2181-3663-vol5-iss2-pp844-852 · Maqolaning asl sahifasi · PDF
| APA | Жасурбек Равзатов, & Dildora Nabieva (2026). Полиморфизм CYP2E1, нутритивный риск и качество жизни при алкогольном циррозе печени. Ўзбекистон метрологияси, 5(2), 844-852. https://doi.org/10.47689/2181-3663-vol5-iss2-pp844-852 |
|---|---|
| GOST (OAK) | Жасурбек Равзатов, Dildora Nabieva Полиморфизм CYP2E1, нутритивный риск и качество жизни при алкогольном циррозе печени // Ўзбекистон метрологияси. – 2026. – T. 5, № 2. – С. 844-852. – DOI: 10.47689/2181-3663-vol5-iss2-pp844-852. |
| MLA | Жасурбек Равзатов, and Dildora Nabieva. “Полиморфизм CYP2E1, нутритивный риск и качество жизни при алкогольном циррозе печени.” Ўзбекистон метрологияси, 5(2), 844-852, 2026. https://doi.org/10.47689/2181-3663-vol5-iss2-pp844-852 |
| Chicago | Жасурбек Равзатов, and Dildora Nabieva. “Полиморфизм CYP2E1, нутритивный риск и качество жизни при алкогольном циррозе печени.” Ўзбекистон метрологияси, 5(2), 844-852 (2026). https://doi.org/10.47689/2181-3663-vol5-iss2-pp844-852 |
| Harvard | Жасурбек Равзатов, and Dildora Nabieva (2026) ‘Полиморфизм CYP2E1, нутритивный риск и качество жизни при алкогольном циррозе печени’, Ўзбекистон метрологияси, 5(2), 844-852. https://doi.org/10.47689/2181-3663-vol5-iss2-pp844-852 |
| BibTeX | @article{article2026,
title = {Полиморфизм CYP2E1, нутритивный риск и качество жизни при алкогольном циррозе печени},
author = {Жасурбек Равзатов and Dildora Nabieva},
journal = {Ўзбекистон метрологияси},
year = {2026},
volume = {5},
number = {2},
pages = {844-852},
doi = {10.47689/2181-3663-vol5-iss2-pp844-852},
url = {https://doi.org/10.47689/2181-3663-vol5-iss2-pp844-852}
} |
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