Objective. To evaluate the prognostic significance of individual blood coagulation factors—fibrinogen A, platelet count, thrombotest grade, and prothrombin index—for rebleeding in patients with acute gastroduodenal ulcer bleeding (AGUB) and to identify the most informative laboratory predictors of recurrence. Materials and Methods. A prospective study included 273 patients with AGUB. Fibrinogen A, platelet count, thrombotest grade, and prothrombin index were assessed dynamically in all patients. The prognostic coefficient (PC) for each parameter was calculated using E. V. Gubler’s sequential analysis method (1978) by comparing patients without rebleeding (n = 251) with those who experienced rebleeding (n = 22). Results. Rebleeding occurred in 22 of 273 patients (8.1%). The highest prognostic value was demonstrated by a thrombotest grade below IV (PC = 1.408; rebleeding probability, 63.6%), a platelet count below 150 × 10⁹/L (PC = 0.813; rebleeding probability, 30.7%), and a fibrinogen A level below 2 g/L (PC = 0.864; rebleeding probability, 33.3%). The prothrombin index showed no significant effect on the rebleeding rate. Conclusion. Thrombocytopenia below 150 × 10⁹/L, a thrombotest grade below IV, and a fibrinogen A level below 2 g/L are independent and the most significant laboratory predictors of gastroduodenal ulcer rebleeding and can be used for the timely determination of indications for active surgical management.
| Mualliflar | Oktyabr Teshaev, Sharif Kurbonov, Muslimbek Ruzibaev, Durdona Ro'ziboyeva, Jafar Jurayev |
|---|---|
| Jurnal | Ўзбекистон метрологияси |
| Nashriyot | Ўзбекистон техник жиҳатдан тартибга солиш агентлиги |
| ISSN | 2181-3663 |
| Nashr sanasi | 2026-06-05 |
| Jild | 5 |
| Son | 3 |
| Betlar | 793-802 |
| Til | O‘zbek |
| Ilmiy soha | Texnika |
| DOI | 10.47689/2181-3663-vol5-iss3-pp793-802 |
| Indeksga qo‘shilgan | 2026-09-02 |
DOI: 10.47689/2181-3663-vol5-iss3-pp793-802 · Maqolaning asl sahifasi · PDF
| APA | Oktyabr Teshaev, Sharif Kurbonov, Muslimbek Ruzibaev, Durdona Ro'ziboyeva, & Jafar Jurayev (2026). Gastroduodenal yara qon ketishlari retsidivini bashorat qilishda qon ivish tizimi omillarining ahamiyati. Ўзбекистон метрологияси, 5(3), 793-802. https://doi.org/10.47689/2181-3663-vol5-iss3-pp793-802 |
|---|---|
| GOST (OAK) | Oktyabr Teshaev va b. Gastroduodenal yara qon ketishlari retsidivini bashorat qilishda qon ivish tizimi omillarining ahamiyati // Ўзбекистон метрологияси. – 2026. – T. 5, № 3. – B. 793-802. – DOI: 10.47689/2181-3663-vol5-iss3-pp793-802. |
| MLA | Oktyabr Teshaev, Sharif Kurbonov, Muslimbek Ruzibaev, Durdona Ro'ziboyeva, and Jafar Jurayev. “Gastroduodenal yara qon ketishlari retsidivini bashorat qilishda qon ivish tizimi omillarining ahamiyati.” Ўзбекистон метрологияси, 5(3), 793-802, 2026. https://doi.org/10.47689/2181-3663-vol5-iss3-pp793-802 |
| Chicago | Oktyabr Teshaev, Sharif Kurbonov, Muslimbek Ruzibaev, Durdona Ro'ziboyeva, and Jafar Jurayev. “Gastroduodenal yara qon ketishlari retsidivini bashorat qilishda qon ivish tizimi omillarining ahamiyati.” Ўзбекистон метрологияси, 5(3), 793-802 (2026). https://doi.org/10.47689/2181-3663-vol5-iss3-pp793-802 |
| Harvard | Oktyabr Teshaev, Sharif Kurbonov, Muslimbek Ruzibaev, Durdona Ro'ziboyeva, and Jafar Jurayev (2026) ‘Gastroduodenal yara qon ketishlari retsidivini bashorat qilishda qon ivish tizimi omillarining ahamiyati’, Ўзбекистон метрологияси, 5(3), 793-802. https://doi.org/10.47689/2181-3663-vol5-iss3-pp793-802 |
| BibTeX | @article{oktyabrteshaev2026,
title = {Gastroduodenal yara qon ketishlari retsidivini bashorat qilishda qon ivish tizimi omillarining ahamiyati},
author = {Oktyabr Teshaev and Sharif Kurbonov and Muslimbek Ruzibaev and Durdona Ro'ziboyeva and Jafar Jurayev},
journal = {Ўзбекистон метрологияси},
year = {2026},
volume = {5},
number = {3},
pages = {793-802},
doi = {10.47689/2181-3663-vol5-iss3-pp793-802},
url = {https://doi.org/10.47689/2181-3663-vol5-iss3-pp793-802}
} |
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