In preterm newborns, incomplete development of the adrenal glands and thymic enlargement in the form of hyperplasia are associated with a reduced ability to mount adequate adaptive responses to extreme stress factors. This condition is manifested by the severe course of acute respiratory distress syndrome (ARDS) and a direct deficiency of the adrenal hormone cortisol. Cortisol deficiency, in turn, leads to impaired lung expansion and incomplete synthesis of surfactant. Morphological examination of the adrenal glands reveals signs of immaturity: the glomerular zones are mostly in a primordial state, the spongiocytes are small with large nuclei and contain few lipid inclusions in the cytoplasm, and the epithelial cells of the reticular layer are characterized by small nuclei and light cytoplasm.
| Mualliflar | Khoshimov Bobur Lukmonovich, Khatamov Rustamjon Islomjonovich |
|---|---|
| Jurnal | Klinik fanlar yilnomasi |
| Nashr sanasi | 2025-11-12 |
| Jild | 2 |
| Son | 3/2 |
| Til | O‘zbek |
Preterm birth, respiratory distress syndrome, adrenal glands, morphology, Преждевременные роды, респираторный дистресс-синдром, надпочечники, морфология, Муддатдан олдинги туғруқ, респиратор дистресс синдром, буйрак усти бези, морфология
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