Clinical and cardiographic changes in patients with acute lymphoblastic leukaemia and methods for their correction

Shonazarova M. A, Urakov K.Z

Klinik fanlar yilnomasi · 2025-yil

Annotatsiya

Objective: To analyze the clinical and electrocardiographic changes in patients with acute lymphoblastic leukemia (ALL) and evaluate the methods of their correction. Materials and Methods: The study included 40 patients aged 18 to 40 years with newly diagnosed ALL who underwent polychemotherapy. ECG and EchoCG were performed before and after treatment. Additional tests included complete blood count, urinalysis, lipid profile, coagulation time, and coagulation profile. Results: Electrocardiographic abnormalities were found in 90% of patients, including sinus tachycardia, extrasystoles, atrial fibrillation, ST segment changes, and QTc prolongation. EchoCG showed reduced left ventricular ejection fraction in 75% of patients. Cardioprotective therapy and regular monitoring improved outcomes. Conclusion: Cardiographic monitoring is essential in ALL treatment to prevent and correct cardiotoxicity. Cardioprotective agents such as ACE inhibitors and dexrazoxane are recommended.

Maqola ma’lumotlari
MualliflarShonazarova M. A, Urakov K.Z
JurnalKlinik fanlar yilnomasi
NashriyotБухоро давлат тиббиёт институти
ISSN2025-2026, 0009-0006
Nashr sanasi2025-11-12
Jild2
Son3/2
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Maqolaning asl sahifasi

Kalit so‘zlar

acute lymphoblastic leukemia, cardiotoxicity, ECG, EchoCG, chemotherapy, cardioprotection, острый лимфобластный лейкоз, ЭКГ, химиотерапия, кардиотоксичность, фракция выброса, acute lymphoblastic leukemia, cardiotoxicity, ECG, EchoCG, chemotherapy, cardioprotection

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAShonazarova M. A, & Urakov K.Z (2025). CLINICAL AND CARDIOGRAPHIC CHANGES IN PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKAEMIA AND METHODS FOR THEIR CORRECTION. Klinik fanlar yilnomasi, 2(3/2). https://tadqiqot.uz/index.php/spjacd/article/view/12879
GOST (OAK)Shonazarova M. A, Urakov K.Z CLINICAL AND CARDIOGRAPHIC CHANGES IN PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKAEMIA AND METHODS FOR THEIR CORRECTION // Klinik fanlar yilnomasi. – 2025. – T. 2, № 3/2.
MLAShonazarova M. A, and Urakov K.Z. “CLINICAL AND CARDIOGRAPHIC CHANGES IN PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKAEMIA AND METHODS FOR THEIR CORRECTION.” Klinik fanlar yilnomasi, 2(3/2), 2025. https://tadqiqot.uz/index.php/spjacd/article/view/12879
ChicagoShonazarova M. A, and Urakov K.Z. “CLINICAL AND CARDIOGRAPHIC CHANGES IN PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKAEMIA AND METHODS FOR THEIR CORRECTION.” Klinik fanlar yilnomasi, 2(3/2) (2025). https://tadqiqot.uz/index.php/spjacd/article/view/12879
HarvardShonazarova M. A, and Urakov K.Z (2025) ‘CLINICAL AND CARDIOGRAPHIC CHANGES IN PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKAEMIA AND METHODS FOR THEIR CORRECTION’, Klinik fanlar yilnomasi, 2(3/2). https://tadqiqot.uz/index.php/spjacd/article/view/12879
BibTeX
@article{shonazarovama2025,
  title = {CLINICAL AND CARDIOGRAPHIC CHANGES IN PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKAEMIA AND METHODS FOR THEIR CORRECTION},
  author = {Shonazarova M. A and Urakov K.Z},
  journal = {Klinik fanlar yilnomasi},
  year = {2025},
  volume = {2},
  number = {3/2},
  url = {https://tadqiqot.uz/index.php/spjacd/article/view/12879}
}

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