Morphological changes in experimental brain injury and their impact on the effectiveness of intensive care

Zhakonkulova S.U, Po’latova Shahnoza Haydarovna

Klinik fanlar yilnomasi · 2026-yil

Annotatsiya

This scientific article experimentally studied the morphological characteristics of hemorrhagic foci at different stages of traumatic brain injury in albino mongrel rats. The aim of the study was to identify histomorphological changes occurring in the brain after mechanical traumatic brain injury and to evaluate their progression over time. Experiments were conducted under isoflurane anesthesia, using a pendulum to create a standard model of mechanical trauma. On days 1, 3, 7, and 14 post-injury, hemorrhage, neuronal degeneration, edema, and microcirculation disturbances in brain tissue were studied using microscopic and histochemical methods. The results showed a predominance of acute hemorrhagic changes in the early stages of traumatic brain injury, followed by the development of reparative processes and gliosis in the later stages. Based on the data obtained, determining the morphological dynamics of hemorrhagic foci serves to improve intensive care strategies for traumatic brain injuries. The study's results are important for the scientific substantiation of diagnostic and therapeutic approaches in modern neurotraumatology.

Maqola ma’lumotlari
MualliflarZhakonkulova S.U, Po’latova Shahnoza Haydarovna
JurnalKlinik fanlar yilnomasi
NashriyotБухоро давлат тиббиёт институти
ISSN2025-2026, 0009-0006
Nashr sanasi2026-01-20
Jild2
Son4/1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Kalit so‘zlar

brain, trauma, hemorrhage, hemorrhage and morphology, головной мозг, травма, кровоизлияние, гемморагия и морфология, miya, travma, qon ketish, qon ketish va morfologiya

Ilmiy soha

Iqtibos keltirish

APAZhakonkulova S.U, & Po’latova Shahnoza Haydarovna (2026). MORPHOLOGICAL CHANGES IN EXPERIMENTAL BRAIN INJURY AND THEIR IMPACT ON THE EFFECTIVENESS OF INTENSIVE CARE. Klinik fanlar yilnomasi, 2(4/1). https://tadqiqot.uz/index.php/spjacd/article/view/13158
GOST (OAK)Zhakonkulova S.U, Po’latova Shahnoza Haydarovna MORPHOLOGICAL CHANGES IN EXPERIMENTAL BRAIN INJURY AND THEIR IMPACT ON THE EFFECTIVENESS OF INTENSIVE CARE // Klinik fanlar yilnomasi. – 2026. – T. 2, № 4/1.
MLAZhakonkulova S.U, and Po’latova Shahnoza Haydarovna. “MORPHOLOGICAL CHANGES IN EXPERIMENTAL BRAIN INJURY AND THEIR IMPACT ON THE EFFECTIVENESS OF INTENSIVE CARE.” Klinik fanlar yilnomasi, 2(4/1), 2026. https://tadqiqot.uz/index.php/spjacd/article/view/13158
ChicagoZhakonkulova S.U, and Po’latova Shahnoza Haydarovna. “MORPHOLOGICAL CHANGES IN EXPERIMENTAL BRAIN INJURY AND THEIR IMPACT ON THE EFFECTIVENESS OF INTENSIVE CARE.” Klinik fanlar yilnomasi, 2(4/1) (2026). https://tadqiqot.uz/index.php/spjacd/article/view/13158
HarvardZhakonkulova S.U, and Po’latova Shahnoza Haydarovna (2026) ‘MORPHOLOGICAL CHANGES IN EXPERIMENTAL BRAIN INJURY AND THEIR IMPACT ON THE EFFECTIVENESS OF INTENSIVE CARE’, Klinik fanlar yilnomasi, 2(4/1). https://tadqiqot.uz/index.php/spjacd/article/view/13158
BibTeX
@article{zhakonkulovasu2026,
  title = {MORPHOLOGICAL CHANGES IN EXPERIMENTAL BRAIN INJURY AND THEIR IMPACT ON THE EFFECTIVENESS OF INTENSIVE CARE},
  author = {Zhakonkulova S.U and Po’latova Shahnoza Haydarovna},
  journal = {Klinik fanlar yilnomasi},
  year = {2026},
  volume = {2},
  number = {4/1},
  url = {https://tadqiqot.uz/index.php/spjacd/article/view/13158}
}

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