Agt T174M and JAK2 V612PHE: the key to vascular complications of long COVID

Агзамходжаева, Н, Исламова, Р, Рузибакиева, М, Абидова, Д, Agzamxodjayeva, N, Islamova, R, Ruzibakieva, M, Abidova, D, Agzamkhodjaeva, N, Islamova, R, Ruzibakieva, M, Abidova, D

Тиббиёт ва спорт · 2026-yil

Annotatsiya

This study examined associations of genetic polymorphisms AGT T174M, JAK2 V612Phe, IL6 -174G>C, and EDN1 Lysl98Asn with Long COVID in patients with arterial hypertension. Genotyping of 174 participants was performed using allele-specific PCR, followed by statistical analysis. The TM genotype of AGT T174M and the GG genotype of JAK2 V6l2Phe were significantly more frequent in patients with Long COVID and hypertension, correlating with reduced levels of miR-155 and miR-28. Polymorphisms ofIL6 and EDN1 showed no statistically significant differences. These findings suggest that AGT T174M and JAK2 V612Phe polymorphisms may represent genetic predisposition factors for more severe vascular manifestations of Long COVID in the context of arterial hypertension.

Maqola ma’lumotlari
MualliflarАгзамходжаева, Н, Исламова, Р, Рузибакиева, М, Абидова, Д, Agzamxodjayeva, N, Islamova, R, Ruzibakieva, M, Abidova, D, Agzamkhodjaeva, N, Islamova, R, Ruzibakieva, M, Abidova, D
JurnalТиббиёт ва спорт
NashriyotЎзбекистон Миллий олимпия қўмитаси хузуридаги, Республика спорт тиббиёти илмий-амалий маркази
ISSN2181-998X
Nashr sanasi2026-06-08
Son1
Betlar146-148
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

Long COVID, артериальная гипертензия, генетический полиморфизм, AGT T174M, JAK2 V612Phe, microRNA, Long COVID, arterial hypertension, genetic polymorphism, AGT T174M, JAK2 V612Phe, microRNA, Long COVID, arterial gipertenziya, genetik polimorfizm, AGT T174M, JAK2 V612Phe, microRNA

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAАгзамходжаева, Н, Исламова, Р, Рузибакиева, М, Абидова, Д, Agzamxodjayeva, N, Islamova, R, Ruzibakieva, M, Abidova, D, Agzamkhodjaeva, N, Islamova, R, Ruzibakieva, M, & Abidova, D (2026). AGT T174M AND JAK2 V612PHE: THE KEY TO VASCULAR COMPLICATIONS OF LONG COVID. Тиббиёт ва спорт, (1), 146-148. https://journal.sportmed.uz/index.php/medsport/article/view/76
GOST (OAK)Агзамходжаева, Н va b. AGT T174M AND JAK2 V612PHE: THE KEY TO VASCULAR COMPLICATIONS OF LONG COVID // Тиббиёт ва спорт. – 2026. – № 1. – P. 146-148.
MLAАгзамходжаева, Н, Исламова, Р, Рузибакиева, М, Абидова, Д, Agzamxodjayeva, N, Islamova, R, Ruzibakieva, M, Abidova, D, Agzamkhodjaeva, N, Islamova, R, Ruzibakieva, M, and Abidova, D. “AGT T174M AND JAK2 V612PHE: THE KEY TO VASCULAR COMPLICATIONS OF LONG COVID.” Тиббиёт ва спорт, (1), 146-148, 2026. https://journal.sportmed.uz/index.php/medsport/article/view/76
ChicagoАгзамходжаева, Н, Исламова, Р, Рузибакиева, М, Абидова, Д, Agzamxodjayeva, N, Islamova, R, Ruzibakieva, M, Abidova, D, Agzamkhodjaeva, N, Islamova, R, Ruzibakieva, M, and Abidova, D. “AGT T174M AND JAK2 V612PHE: THE KEY TO VASCULAR COMPLICATIONS OF LONG COVID.” Тиббиёт ва спорт, (1), 146-148 (2026). https://journal.sportmed.uz/index.php/medsport/article/view/76
HarvardАгзамходжаева, Н, Исламова, Р, Рузибакиева, М, Абидова, Д, Agzamxodjayeva, N, Islamova, R, Ruzibakieva, M, Abidova, D, Agzamkhodjaeva, N, Islamova, R, Ruzibakieva, M, and Abidova, D (2026) ‘AGT T174M AND JAK2 V612PHE: THE KEY TO VASCULAR COMPLICATIONS OF LONG COVID’, Тиббиёт ва спорт, (1), 146-148. https://journal.sportmed.uz/index.php/medsport/article/view/76
BibTeX
@article{article2026,
  title = {AGT T174M AND JAK2 V612PHE: THE KEY TO VASCULAR COMPLICATIONS OF LONG COVID},
  author = {Агзамходжаева, Н and Исламова, Р and Рузибакиева, М and Абидова, Д and Agzamxodjayeva, N and Islamova, R and Ruzibakieva, M and Abidova, D and Agzamkhodjaeva, N and Islamova, R and Ruzibakieva, M and Abidova, D},
  journal = {Тиббиёт ва спорт},
  year = {2026},
  number = {1},
  pages = {146-148},
  url = {https://journal.sportmed.uz/index.php/medsport/article/view/76}
}

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