Resume: This original article presents data on the study of liver parenchymal stiffness using elastography in obese and normal-weight children. The obtained results can be incorporated into the practice of pediatricians and pediatric gastroenterologists. Objective: To evaluate the diagnostic efficacy of liver ultrasound elastography in patients with obesity and non-alcoholic fatty liver disease (NAFLD). Materials and Methods: Sixty-eight children with obesity and non-alcoholic fatty liver disease were studied. All children underwent liver parenchymal stiffness testing using the Fibroscan device. Study results: These results have significant prognostic value and confirm the pathogenetic role of NAFLD in the development of fibrotic liver changes in children with visceral obesity associated with impaired carbohydrate and lipid metabolism. Elevated ALT activity reflects impaired liver metabolism and is accompanied by the development of liver inflammation induced by hyperleptinemia and leptin resistance. Conclusions: The combination of metabolic disturbances associated with inflammation in children with visceral obesity contributes to the progression of liver steatosis and the development of fibrosis, which creates the preconditions for the subsequent development of steatohepatitis.
| Mualliflar | Turaeva, Dilafruz, Тураева, Дилафруз, Turayeva, Dilafruz |
|---|---|
| Jurnal | Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi |
| Nashriyot | Андижон давлат тиббиёт институти |
| ISSN | 2181-3612 |
| Nashr sanasi | 2025-10-25 |
| Jild | 4 |
| Son | 5 |
| Betlar | 41-44 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| DOI | 10.56121/2181-3612-2025-5-41-44 |
| Indeksga qo‘shilgan | 2026-08-26 |
DOI: 10.56121/2181-3612-2025-5-41-44 · Maqolaning asl sahifasi
non-alcoholic fatty liver disease, obesity, children, fibrosis, Young's modulus, не алкогольная жировая болезнь печени, ожирение, дети, фиброз, модуль Юнга, alkogolsiz yog'li jigar kasalligi, semizlik, bolalar, fibroz, Yang moduli
| APA | Turaeva, Dilafruz, Тураева, Дилафруз, & Turayeva, Dilafruz (2025). LIVER STIFFNESS METHODS IN CHILDREN WITH OBESITY USING SHEAR WAVE ELASTOGRAPHY. Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(5), 41-44. https://doi.org/10.56121/2181-3612-2025-5-41-44 |
|---|---|
| GOST (OAK) | Turaeva, Dilafruz, Тураева, Дилафруз, Turayeva, Dilafruz LIVER STIFFNESS METHODS IN CHILDREN WITH OBESITY USING SHEAR WAVE ELASTOGRAPHY // Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi. – 2025. – T. 4, № 5. – P. 41-44. – DOI: 10.56121/2181-3612-2025-5-41-44. |
| MLA | Turaeva, Dilafruz, Тураева, Дилафруз, and Turayeva, Dilafruz. “LIVER STIFFNESS METHODS IN CHILDREN WITH OBESITY USING SHEAR WAVE ELASTOGRAPHY.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(5), 41-44, 2025. https://doi.org/10.56121/2181-3612-2025-5-41-44 |
| Chicago | Turaeva, Dilafruz, Тураева, Дилафруз, and Turayeva, Dilafruz. “LIVER STIFFNESS METHODS IN CHILDREN WITH OBESITY USING SHEAR WAVE ELASTOGRAPHY.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(5), 41-44 (2025). https://doi.org/10.56121/2181-3612-2025-5-41-44 |
| Harvard | Turaeva, Dilafruz, Тураева, Дилафруз, and Turayeva, Dilafruz (2025) ‘LIVER STIFFNESS METHODS IN CHILDREN WITH OBESITY USING SHEAR WAVE ELASTOGRAPHY’, Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(5), 41-44. https://doi.org/10.56121/2181-3612-2025-5-41-44 |
| BibTeX | @article{turaevadilafruz2025,
title = {LIVER STIFFNESS METHODS IN CHILDREN WITH OBESITY USING SHEAR WAVE ELASTOGRAPHY},
author = {Turaeva, Dilafruz and Тураева, Дилафруз and Turayeva, Dilafruz},
journal = {Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi},
year = {2025},
volume = {4},
number = {5},
pages = {41-44},
doi = {10.56121/2181-3612-2025-5-41-44},
url = {https://doi.org/10.56121/2181-3612-2025-5-41-44}
} |
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