The state of immunoreactivity in children depending on types of nutrition

Bobojonov, Turdiqul, Sultanova, Nafisa, Otaboyeva, Shahnoza, Abdunazarov, Mirjalol, Бобомуратов, Турдиқул, Султанова, Нафиса, Отабоева, Шахноза, Абдуназаров, Миржалол, Bobojonov, Turdiqul, Sultanova, Nafisa, Otaboyeva, Shahnoza, Abdunazarov, Mirjalol

Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-yil

Annotatsiya

Relevance.Exclusive breastfeeding during the first six months of life plays a decisive role in the development of the immune system and healthy growth of children. The aim of the study. To study and compare the immunological status of children depending on the type of feeding. Materials and methods of the study. A total of 123 children with different feeding patterns were examined. Blood tests and immunological assessments were performed using monoclonal antibodies CD3, CD4, CD8, CD16, CD23, CD25, CD38, and CD95 to evaluate cellular and humoral immunity. Research results. Artificially fed children demonstrated a significant increase in lymphocytes, leukocytes, and CD3+ cells, along with a decrease in CD4+. Levels of B-lymphocytes, CD16+, CD23+, and CD38+ were elevated, indicating activation of apoptosis. A marked imbalance of IgM and IgA, increased circulating immune complexes, and higher allergization factors were observed in artificially fed groups. Conclusion. Immunological changes in children are closely related to the type of feeding. Breastfeeding supports the maintenance of immune balance, whereas artificial feeding is associated with physiological depletion of immune system reserves.

Maqola ma’lumotlari
MualliflarBobojonov, Turdiqul, Sultanova, Nafisa, Otaboyeva, Shahnoza, Abdunazarov, Mirjalol, Бобомуратов, Турдиқул, Султанова, Нафиса, Отабоева, Шахноза, Абдуназаров, Миржалол, Bobojonov, Turdiqul, Sultanova, Nafisa, Otaboyeva, Shahnoza, Abdunazarov, Mirjalol
JurnalMedical science of Uzbekistan / O'zbekiston tibbiyot ilmi
NashriyotАндижон давлат тиббиёт институти
ISSN2181-3612
Nashr sanasi2025-12-24
Jild4
Son6
Betlar20-23
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-3612-2025-6-20-23
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-3612-2025-6-20-23 · Maqolaning asl sahifasi

Kalit so‘zlar

breastfeeding, artificial feeding, immunological status, lymphocytes, apoptosis, грудное вскармливание, искусственное вскармливание, иммунологический статус, лимфоциты, апоптоз, ona suti bilan oziqlantirish, sun’iy oziqlantirish, immunologik holat, limfotsitlar, apoptoz

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APABobojonov, Turdiqul, Sultanova, Nafisa, Otaboyeva, Shahnoza, Abdunazarov, Mirjalol, Бобомуратов, Турдиқул, Султанова, Нафиса, Отабоева, Шахноза, Абдуназаров, Миржалол, Bobojonov, Turdiqul, Sultanova, Nafisa, Otaboyeva, Shahnoza, & Abdunazarov, Mirjalol (2025). THE STATE OF IMMUNOREACTIVITY IN CHILDREN DEPENDING ON TYPES OF NUTRITION. Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 20-23. https://doi.org/10.56121/2181-3612-2025-6-20-23
GOST (OAK)Bobojonov, Turdiqul va b. THE STATE OF IMMUNOREACTIVITY IN CHILDREN DEPENDING ON TYPES OF NUTRITION // Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi. – 2025. – T. 4, № 6. – P. 20-23. – DOI: 10.56121/2181-3612-2025-6-20-23.
MLABobojonov, Turdiqul, Sultanova, Nafisa, Otaboyeva, Shahnoza, Abdunazarov, Mirjalol, Бобомуратов, Турдиқул, Султанова, Нафиса, Отабоева, Шахноза, Абдуназаров, Миржалол, Bobojonov, Turdiqul, Sultanova, Nafisa, Otaboyeva, Shahnoza, and Abdunazarov, Mirjalol. “THE STATE OF IMMUNOREACTIVITY IN CHILDREN DEPENDING ON TYPES OF NUTRITION.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 20-23, 2025. https://doi.org/10.56121/2181-3612-2025-6-20-23
ChicagoBobojonov, Turdiqul, Sultanova, Nafisa, Otaboyeva, Shahnoza, Abdunazarov, Mirjalol, Бобомуратов, Турдиқул, Султанова, Нафиса, Отабоева, Шахноза, Абдуназаров, Миржалол, Bobojonov, Turdiqul, Sultanova, Nafisa, Otaboyeva, Shahnoza, and Abdunazarov, Mirjalol. “THE STATE OF IMMUNOREACTIVITY IN CHILDREN DEPENDING ON TYPES OF NUTRITION.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 20-23 (2025). https://doi.org/10.56121/2181-3612-2025-6-20-23
HarvardBobojonov, Turdiqul, Sultanova, Nafisa, Otaboyeva, Shahnoza, Abdunazarov, Mirjalol, Бобомуратов, Турдиқул, Султанова, Нафиса, Отабоева, Шахноза, Абдуназаров, Миржалол, Bobojonov, Turdiqul, Sultanova, Nafisa, Otaboyeva, Shahnoza, and Abdunazarov, Mirjalol (2025) ‘THE STATE OF IMMUNOREACTIVITY IN CHILDREN DEPENDING ON TYPES OF NUTRITION’, Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 20-23. https://doi.org/10.56121/2181-3612-2025-6-20-23
BibTeX
@article{bobojonovturdiqul2025,
  title = {THE STATE OF IMMUNOREACTIVITY IN CHILDREN DEPENDING ON TYPES OF NUTRITION},
  author = {Bobojonov, Turdiqul and Sultanova, Nafisa and Otaboyeva, Shahnoza and Abdunazarov, Mirjalol and Бобомуратов, Турдиқул and Султанова, Нафиса and Отабоева, Шахноза and Абдуназаров, Миржалол and Bobojonov, Turdiqul and Sultanova, Nafisa and Otaboyeva, Shahnoza and Abdunazarov, Mirjalol},
  journal = {Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi},
  year = {2025},
  volume = {4},
  number = {6},
  pages = {20-23},
  doi = {10.56121/2181-3612-2025-6-20-23},
  url = {https://doi.org/10.56121/2181-3612-2025-6-20-23}
}

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