Predicting the possibility of developing multiorgan deficiency syndrome in patients with peritonitis

Mamatkulov, Ixtiyor, Xaydarov, Muzaffar, Beknazarov, Amir, Маматкулов, Ихтиёр, Хайдаров, Музаффар, Бекназаров, Амир, Mamatkulov, Ixtiyor, Xaydarov, Muzaffar, Beknazarov, Amir

Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-yil

Annotatsiya

Study Objective: To determine the feasibility of predicting the development of multiple organ dysfunction syndrome (MODS) in children with peritonitis based on an analysis of blood coagulation (hemostasis) parameters. Materials and Methods: The study included 52 children aged 6 to 18 years admitted to the surgical department of the Tashkent State Medical University, with a diagnosis of peritonitis confirmed during surgery. Patients were divided into three groups: Group I (22 children): with localized peritonitis. Group II (22 children): with generalized peritonitis but without obvious clinical and laboratory signs of sepsis (with one or two signs of a systemic inflammatory response). Group III (8 children): with generalized peritonitis and pronounced clinical and laboratory signs of sepsis. Results: Initial analysis showed that all patients with peritonitis had increased blood coagulation compared to normal. Further observation of the disease revealed the following: Children in Group I successfully managed peritonitis thanks to the therapy administered, and they did not develop POES. In Group II, POES developed in 10% of patients, and in 50% of patients in Group III. In cases of POES development, a change in treatment strategy was required. Conclusion: A study of the blood coagulation system in children with peritonitis allowed us to identify three types of the body's response to abdominal infection: Favorable type: characterized by the absence of POES and the presence of no more than two signs of a systemic inflammatory response. Questionable type: accompanied by the development of POES in 10% of cases, with no more than two signs of a systemic inflammatory response. Unfavorable type: associated with the development of POES in 50% of cases and the presence of more than two signs of a systemic inflammatory response, indicating abdominal (peritoneal) sepsis.

Maqola ma’lumotlari
MualliflarMamatkulov, Ixtiyor, Xaydarov, Muzaffar, Beknazarov, Amir, Маматкулов, Ихтиёр, Хайдаров, Музаффар, Бекназаров, Амир, Mamatkulov, Ixtiyor, Xaydarov, Muzaffar, Beknazarov, Amir
JurnalMedical science of Uzbekistan / O'zbekiston tibbiyot ilmi
NashriyotАндижон давлат тиббиёт институти
ISSN2181-3612
Nashr sanasi2025-12-24
Jild4
Son6
Betlar53-58
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-3612-2025-6-53-58
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-3612-2025-6-53-58 · Maqolaning asl sahifasi

Kalit so‘zlar

peritonitis, multiple organ failure, children, hemostasis, fibrinolysis, перитонит, полиорганная недостаточность, дети, гемостаз, фибринолиз, peritonit, ko'p organli yetishmovchilik, bolalar, gemostaz, fibrinoliz

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAMamatkulov, Ixtiyor, Xaydarov, Muzaffar, Beknazarov, Amir, Маматкулов, Ихтиёр, Хайдаров, Музаффар, Бекназаров, Амир, Mamatkulov, Ixtiyor, Xaydarov, Muzaffar, & Beknazarov, Amir (2025). PREDICTING THE POSSIBILITY OF DEVELOPING MULTIORGAN DEFICIENCY SYNDROME IN PATIENTS WITH PERITONITIS. Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 53-58. https://doi.org/10.56121/2181-3612-2025-6-53-58
GOST (OAK)Mamatkulov, Ixtiyor va b. PREDICTING THE POSSIBILITY OF DEVELOPING MULTIORGAN DEFICIENCY SYNDROME IN PATIENTS WITH PERITONITIS // Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi. – 2025. – T. 4, № 6. – P. 53-58. – DOI: 10.56121/2181-3612-2025-6-53-58.
MLAMamatkulov, Ixtiyor, Xaydarov, Muzaffar, Beknazarov, Amir, Маматкулов, Ихтиёр, Хайдаров, Музаффар, Бекназаров, Амир, Mamatkulov, Ixtiyor, Xaydarov, Muzaffar, and Beknazarov, Amir. “PREDICTING THE POSSIBILITY OF DEVELOPING MULTIORGAN DEFICIENCY SYNDROME IN PATIENTS WITH PERITONITIS.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 53-58, 2025. https://doi.org/10.56121/2181-3612-2025-6-53-58
ChicagoMamatkulov, Ixtiyor, Xaydarov, Muzaffar, Beknazarov, Amir, Маматкулов, Ихтиёр, Хайдаров, Музаффар, Бекназаров, Амир, Mamatkulov, Ixtiyor, Xaydarov, Muzaffar, and Beknazarov, Amir. “PREDICTING THE POSSIBILITY OF DEVELOPING MULTIORGAN DEFICIENCY SYNDROME IN PATIENTS WITH PERITONITIS.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 53-58 (2025). https://doi.org/10.56121/2181-3612-2025-6-53-58
HarvardMamatkulov, Ixtiyor, Xaydarov, Muzaffar, Beknazarov, Amir, Маматкулов, Ихтиёр, Хайдаров, Музаффар, Бекназаров, Амир, Mamatkulov, Ixtiyor, Xaydarov, Muzaffar, and Beknazarov, Amir (2025) ‘PREDICTING THE POSSIBILITY OF DEVELOPING MULTIORGAN DEFICIENCY SYNDROME IN PATIENTS WITH PERITONITIS’, Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 53-58. https://doi.org/10.56121/2181-3612-2025-6-53-58
BibTeX
@article{mamatkulovixtiyor2025,
  title = {PREDICTING THE POSSIBILITY OF DEVELOPING MULTIORGAN DEFICIENCY SYNDROME IN PATIENTS WITH PERITONITIS},
  author = {Mamatkulov, Ixtiyor and Xaydarov, Muzaffar and Beknazarov, Amir and Маматкулов, Ихтиёр and Хайдаров, Музаффар and Бекназаров, Амир and Mamatkulov, Ixtiyor and Xaydarov, Muzaffar and Beknazarov, Amir},
  journal = {Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi},
  year = {2025},
  volume = {4},
  number = {6},
  pages = {53-58},
  doi = {10.56121/2181-3612-2025-6-53-58},
  url = {https://doi.org/10.56121/2181-3612-2025-6-53-58}
}

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