Risk factors for the development and features of the course of urate nephropathy in frequently ill children

Nurmatova, Nargiza, Nurmatov, Ulugbek, Нурматова, Наргиза, Нурматов, Улугбек, Nurmatova, Nargiza, Nurmatov, Ulugbek

Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-yil

Annotatsiya

Objective: To determine the prevalence, risk factors, and clinical features of urate nephropathy (UN) in frequently ill children (FIC). Materials and Methods: The study was conducted at the multidisciplinary clinic of Tashkent State Medical University, in the Department of Pediatric Nephrology, during the period from 2022 to 2024. At Stage I, a retrospective, in-depth analysis of the medical records of 1,323 children aged 3 to 12 years who received inpatient treatment was carried out. At Stage II, a comprehensive clinical examination was conducted on 120 children with a confirmed diagnosis of UN. Results: Among frequently ill children, diseases of the urinary system, including urate nephropathy, occur significantly more often than in healthy children. In FIC, UN is commonly associated with background diseases such as tonsillitis, bronchitis, gastroduodenitis, and others, and is characterized by marked seasonality. The main risk factors for the development of the disease include maternal comorbidities, which may increase the likelihood of kidney tissue pathologies in the child in the future. In children with UN, clinical manifestations show age-specific features depending on the developmental stage of the child. Conclusion: To prevent complications of urate nephropathy in frequently ill children, early detection of urate metabolism disorders and timely correction are essential.

Maqola ma’lumotlari
MualliflarNurmatova, Nargiza, Nurmatov, Ulugbek, Нурматова, Наргиза, Нурматов, Улугбек, Nurmatova, Nargiza, Nurmatov, Ulugbek
JurnalMedical science of Uzbekistan / O'zbekiston tibbiyot ilmi
NashriyotАндижон давлат тиббиёт институти
ISSN2181-3612
Nashr sanasi2025-12-24
Jild4
Son6
Betlar59-65
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-3612-2025-6-59-65
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-3612-2025-6-59-65 · Maqolaning asl sahifasi

Kalit so‘zlar

frequently ill children, urate nephropathy, clinical features, risk factors, часто болеющие дети, уратная нефропатия, клиника, факторы риска, tez-tez kasallanuvchan bolalar, uratli nefropatiya, klinik belgilari, xavf omillari

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APANurmatova, Nargiza, Nurmatov, Ulugbek, Нурматова, Наргиза, Нурматов, Улугбек, Nurmatova, Nargiza, & Nurmatov, Ulugbek (2025). RISK FACTORS FOR THE DEVELOPMENT AND FEATURES OF THE COURSE OF URATE NEPHROPATHY IN FREQUENTLY ILL CHILDREN. Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 59-65. https://doi.org/10.56121/2181-3612-2025-6-59-65
GOST (OAK)Nurmatova, Nargiza va b. RISK FACTORS FOR THE DEVELOPMENT AND FEATURES OF THE COURSE OF URATE NEPHROPATHY IN FREQUENTLY ILL CHILDREN // Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi. – 2025. – T. 4, № 6. – P. 59-65. – DOI: 10.56121/2181-3612-2025-6-59-65.
MLANurmatova, Nargiza, Nurmatov, Ulugbek, Нурматова, Наргиза, Нурматов, Улугбек, Nurmatova, Nargiza, and Nurmatov, Ulugbek. “RISK FACTORS FOR THE DEVELOPMENT AND FEATURES OF THE COURSE OF URATE NEPHROPATHY IN FREQUENTLY ILL CHILDREN.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 59-65, 2025. https://doi.org/10.56121/2181-3612-2025-6-59-65
ChicagoNurmatova, Nargiza, Nurmatov, Ulugbek, Нурматова, Наргиза, Нурматов, Улугбек, Nurmatova, Nargiza, and Nurmatov, Ulugbek. “RISK FACTORS FOR THE DEVELOPMENT AND FEATURES OF THE COURSE OF URATE NEPHROPATHY IN FREQUENTLY ILL CHILDREN.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 59-65 (2025). https://doi.org/10.56121/2181-3612-2025-6-59-65
HarvardNurmatova, Nargiza, Nurmatov, Ulugbek, Нурматова, Наргиза, Нурматов, Улугбек, Nurmatova, Nargiza, and Nurmatov, Ulugbek (2025) ‘RISK FACTORS FOR THE DEVELOPMENT AND FEATURES OF THE COURSE OF URATE NEPHROPATHY IN FREQUENTLY ILL CHILDREN’, Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 59-65. https://doi.org/10.56121/2181-3612-2025-6-59-65
BibTeX
@article{nurmatovanargiza2025,
  title = {RISK FACTORS FOR THE DEVELOPMENT AND FEATURES OF THE COURSE OF URATE NEPHROPATHY IN FREQUENTLY ILL CHILDREN},
  author = {Nurmatova, Nargiza and Nurmatov, Ulugbek and Нурматова, Наргиза and Нурматов, Улугбек and Nurmatova, Nargiza and Nurmatov, Ulugbek},
  journal = {Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi},
  year = {2025},
  volume = {4},
  number = {6},
  pages = {59-65},
  doi = {10.56121/2181-3612-2025-6-59-65},
  url = {https://doi.org/10.56121/2181-3612-2025-6-59-65}
}

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