Current perspectives on inflammatory bronchopulmonary diseases with airway obstruction in children

Agzamova, Shoira, Abdurashidova, Xolida, Агзамова, Шоира, Абдурашидова, Холида, Agzamova, Shoira, Abdurashidova, Xolida

Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-yil

Annotatsiya

Relevance. Inflammatory bronchopulmonary diseases remain among the leading causes of morbidity in children, particularly those under three years of age. The increasing incidence of bronchial obstruction, antibiotic resistance, and environmental pollution has elevated the clinical and public health significance of this issue. Aim. To explore modern aspects of pathogenesis, clinical features, and therapeutic approaches in children with inflammatory bronchopulmonary diseases accompanied by airway obstruction. Materials and Methods. A review of current national and international literature was conducted, including data on the prevalence of bronchiolitis, acute bronchitis, and community-acquired pneumonia in early childhood, etiological factors (viral and bacterial agents), and recent advances in treatment strategies and clinical recommendations. Results. Respiratory viruses, particularly RSV, metapneumovirus, and coronavirus, remain the dominant etiological factors. The inflammatory process is closely associated with impaired mucociliary clearance, elevated proteolytic activity, and airway remodeling. Environmental pollutants and passive smoking exacerbate disease severity. Pathogenetically targeted therapy — including enzymatic airway sanitation and rational antibiotic use — plays a critical role in management. Conclusions. Early detection and comprehensive treatment of inflammatory bronchopulmonary diseases in children reduce the risk of chronic airway remodeling and improve outcomes. Preventive strategies should focus on viral infection control, environmental health, and the development of pediatric rehabilitation programs.

Maqola ma’lumotlari
MualliflarAgzamova, Shoira, Abdurashidova, Xolida, Агзамова, Шоира, Абдурашидова, Холида, Agzamova, Shoira, Abdurashidova, Xolida
JurnalMedical science of Uzbekistan / O'zbekiston tibbiyot ilmi
NashriyotАндижон давлат тиббиёт институти
ISSN2181-3612
Nashr sanasi2025-12-24
Jild4
Son6
Betlar04-11
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-3612-2025-6-04-11
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-3612-2025-6-04-11 · Maqolaning asl sahifasi

Kalit so‘zlar

children, bronchiolitis, acute bronchitis, community-acquired pneumonia, obstructive syndrome, mucociliary clearance, proteolytic activity, дети, бронхиолит, острый бронхит, внебольничная пневмония, обструктивный синдром, мукоцилиарный клиренс, протеолитическая активность, bolalar, bronxiolit, o‘tkir bronxit, kasalxona tashqarisidagi pnevmoniya, obstruktiv sindrom, mukotsiliar klirens, proteolitik faollik

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAAgzamova, Shoira, Abdurashidova, Xolida, Агзамова, Шоира, Абдурашидова, Холида, Agzamova, Shoira, & Abdurashidova, Xolida (2025). CURRENT PERSPECTIVES ON INFLAMMATORY BRONCHOPULMONARY DISEASES WITH AIRWAY OBSTRUCTION IN CHILDREN. Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 04-11. https://doi.org/10.56121/2181-3612-2025-6-04-11
GOST (OAK)Agzamova, Shoira va b. CURRENT PERSPECTIVES ON INFLAMMATORY BRONCHOPULMONARY DISEASES WITH AIRWAY OBSTRUCTION IN CHILDREN // Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi. – 2025. – T. 4, № 6. – P. 04-11. – DOI: 10.56121/2181-3612-2025-6-04-11.
MLAAgzamova, Shoira, Abdurashidova, Xolida, Агзамова, Шоира, Абдурашидова, Холида, Agzamova, Shoira, and Abdurashidova, Xolida. “CURRENT PERSPECTIVES ON INFLAMMATORY BRONCHOPULMONARY DISEASES WITH AIRWAY OBSTRUCTION IN CHILDREN.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 04-11, 2025. https://doi.org/10.56121/2181-3612-2025-6-04-11
ChicagoAgzamova, Shoira, Abdurashidova, Xolida, Агзамова, Шоира, Абдурашидова, Холида, Agzamova, Shoira, and Abdurashidova, Xolida. “CURRENT PERSPECTIVES ON INFLAMMATORY BRONCHOPULMONARY DISEASES WITH AIRWAY OBSTRUCTION IN CHILDREN.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 04-11 (2025). https://doi.org/10.56121/2181-3612-2025-6-04-11
HarvardAgzamova, Shoira, Abdurashidova, Xolida, Агзамова, Шоира, Абдурашидова, Холида, Agzamova, Shoira, and Abdurashidova, Xolida (2025) ‘CURRENT PERSPECTIVES ON INFLAMMATORY BRONCHOPULMONARY DISEASES WITH AIRWAY OBSTRUCTION IN CHILDREN’, Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(6), 04-11. https://doi.org/10.56121/2181-3612-2025-6-04-11
BibTeX
@article{agzamovashoira2025,
  title = {CURRENT PERSPECTIVES ON INFLAMMATORY BRONCHOPULMONARY DISEASES WITH AIRWAY OBSTRUCTION IN CHILDREN},
  author = {Agzamova, Shoira and Abdurashidova, Xolida and Агзамова, Шоира and Абдурашидова, Холида and Agzamova, Shoira and Abdurashidova, Xolida},
  journal = {Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi},
  year = {2025},
  volume = {4},
  number = {6},
  pages = {04-11},
  doi = {10.56121/2181-3612-2025-6-04-11},
  url = {https://doi.org/10.56121/2181-3612-2025-6-04-11}
}

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