The scientific and practical journal “Medical Science of Uzbekistan” (ISSN: 2181-3612) is a peer-reviewed open-access academic publication dedicated to the development of clinical medicine, biomedical research, and the healthcare system.
- THE ROLE OF SOD2 GENE ALA16VAL POLYMORPHISM IN THE DEVELOPMENT OF MYELOPROLIFERATIVE NEOPLASIA IN KHOREZM REGION
Jumaboeva, Marjuba, Boboev, Kodirjon, Matmurodov, Rustambek, Jumanazarova, Shaxzoda, Жумабоева, Марғуба, Бобоев, Кодиржон, Матмуродов, Рустамбек, Жуманазарова, Шахзода, Jumaboeva, · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-08-28
Objective: To assess the influence of allelic and genotypic variants of the Ala16Val polymorphism in the SOD2 gene on the development of myeloproliferative neoplasms (MPNs). Materials and methods: A study was…
- IMPROVING THE EFFECTIVENESS OF PREVENTION AND TREATMENT METHODS FOR INFLAMMATORY COMPLICATIONS AFTER COMPLEX TOOTH EXTRACTION
Bekmuratov, Lukmon, Ashrapov, Yosinkhon, Бекмуратов, Лукмон, Ёсинхон, Bekmuratov, Luqmon, Ashrapov, Yosinxon · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-08-28
Inflammatory complications following complex tooth extraction remain among the most common and clinically significant issues in outpatient oral and maxillofacial surgery. This review explores the etiology and…
- SERUM CYSTATIN C FOR RISK STRATIFICATION IN PATIENTS WITH PREDIABETES
Yusupova, Shakhnоza, Chartakov, Akramjon, Юсупова, Шахноза, Чартаков, Акрамжон, Yusupova, Shaxnoza, Chartakov, Akramjon · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
The aim of the investigation is to study the value of Cystatin-C among patients with prediabetes for risk stratification. Material and methods of the study. Our study included 55 people aged 18 to 65 years…
- DISSEMINATED PULMONARY TUBERCULOSIS IN HIV-INFECTED PATIENTS
Khodjiyeva, Sevginoz, Ходжиева, Севгиноз, Xodjiyeva, Sevginoz · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Relevance.The present study is aimed at reviewing the clinical, radiological and immunological features of disseminated pulmonary tuberculosis in patients with HIV infection. Amid the growing HIV pandemic/AIDS and the…
- OPTIMIZATION OF TREATMENT FOR PATIENTS WITH DRUG-RESISTANT PULMONARY TUBERCULOSIS
Khodjiyeva, Sevginoz, Ходжиева, Севгиноз, Xodjiyeva, Sevginoz · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Relevance.Drug-resistant pulmonary tuberculosis (DR-TB) remains one of the most serious threats to public health, particularly in resource-limited and transitional economies. Resistance of Mycobacterium tuberculosis to…
- MARKERS OF ENDOTHELIAL DYSFUNCTION IN CHILDREN WITH OBESITY
Ibragimova, Elnara, Garifulina, Liliya, Ибрагимова, Эльнара, Лиля, Ibragimova, Elnara, Garifulina, Liliya · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Endothelial dysfunction plays a leading role in the progression of cardiovascular disease in children with obesity. The article discusses the prognostic values of early markers of endothelial dysfunction in children…
- COMPARATIVE DIAGNOSTICS OF BRONCHOPULMONARY COMPLICATIONS IN YOUNG CHILDREN WITH WHOOPING COUGH
Sultonov, Ravshan, Qurbonov, Tuqtash, Qurbonova, Gulnoza, Султонов, Равшан, Курбонов, Тукташ, Курбонова, Гульноза, Sultonov, Ravshan, Qurbonov, Tuqtash, Qurbonova, Gulnoza · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Whooping cough remains one of the leading causes of infant mortality worldwide. This article presents a comparative diagnosis of bronchopulmonary complications in young children infected with respiratory syncytial virus…
- MODERN CONCEPTS OF NECROTIZING ENTEROCOLITIS IN NEWBORNS
Nabieva, Diyora, Набиева, Диёра, Nabieva, Diyora · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Relevance. Necrotizing enterocolitis (NEC) remains one of the most serious causes of morbidity and mortality among premature infants. Despite the progress in neonatology, the incidence of NEC ranges from 1% to 7%, and…
- MANAGEMENT AND OUTCOMES OF HOSPITALISED CHILDREN WITH COMMUNITY-ACQUIRED PNEUMONIA COMPLICATED BY PLEURAL EFFUSION
Aminova, Nigina, Аминова, Нигина, Aminova, Nigina · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Abstract: The aim of this study was to investigate the hospitalisation of children with community-acquired pneumonia complicated by pleural effusion. Children without significant comorbidities, aged less than 18 years…
- FEATURES OF CHANGES IN METABOLIC PARAMETERS AND DNA METHYLATION IN CHILDREN AGED 7-10 YEARS ENGAGED IN SWIMMING
Babich, Svyatoslav, Aleynik, Vladimir, Бабич, Святослав, Алейник, Владимир, Babich, Svyatoslav, Aleynik, Vladimir · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Many studies conducted with athletes do not take into account the features of adaptive changes in metabolism. This leads to ambiguity and contradictory data on many indicators in response to a single physical load. This…
- FEATURES OF CHANGES IN IMMUNOLOGICAL PARAMETERS AND DNA METHYLATION IN CHILDREN AGED 7-10 YEARS ENGAGED IN SWIMMING
Babich, Svyatoslav, Aleynik, Vladimir, Бабич, Святослав, Алейник, Владимир, Babich, Svyatoslav, Aleynik, Vladimir · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
The article deals with the features of adaptive processes for changing immunological parameters and epigenetic DNA methylation in children aged 7-10 years who are engaged in swimming. The aim of the study: to study the…
- IRRIGATION SOLUTIONS IN CLINICAL ENDODONTICS: TYPES, PROPERTIES, AND ACTIVATION MECHANISMS
Sattarov, Islomjon, Саттаров, Исломжон, Sattarov, Islomjon · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Relevance. Effective disinfection of root canals is one of the key factors for successful endodontic treatment. The complex anatomical structure of the canals, formation of necrotic tissue layers, and the presence of…
- ASSOCIATION OF THE Gln27Glu POLYMORPHISM OF THE β2-ADRENOCEPTOR GENE WITH LIPID METABOLISM FEATURES IN PATIENTS WITH BRONCHIAL ASTHMA
Turdibekov, Khusan, Suyunova, Gulshan, Ibragimov, Sanjarbek, Турдибеков, Хусан, Суюнова, Гульшан, Ибрагимов, Санжарбек, Turdibekov, Xusan, Suyunova, Gulshan, Ibragimov, Sanjarbek · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Relevance. Considering the key role of β₂-adrenoceptors in bronchodilation mechanisms, as well as their involvement in the regulation of metabolic processes, the analysis of genetic variants of the β₂-adrenoceptor gene…
- CLINICAL MANIFESTATIONS OF CENTRAL NERVOUS SYSTEM DAMAGE IN NEWBORNS, DEPENDING ON THE SEVERITY OF PERINATAL ENCEPHALOPATHY
Nabieva, Shoxista, Набиева, Шохиста, Nabieva, Shoxista · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
120 newborns with moderate and severe perinatal CNS lesions who were in the neonatal pathology department were examined. The study showed a high reliable incidence of perinatal CNS damage in newborns in the studied…
- THE IMPORTANCE OF MODERN DIAGNOSTIC METHODS IN DETECTING AND TREATING MYCOPLASMA PNEUMONIA IN CHILDREN
Kholikova, Gulnoz, Холикова, Гулноз, Xoliqova, Gulnoz · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Introduction. Late detection of atypical forms of community-acquired pneumonia is one of the urgent problems and leads to an increase in the duration of treatment. This is due to the late detection of SARS by family…
- POSTOPERATIVE COMPLICATIONS OF ADENOTONSILLOTOMY: FREQUENCY AND PREVENTION
Shamatov, Islom, Шаматов, Ислом, Shamatov, Islom · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Adenotonsillotomy is one of the most commonly performed surgical procedures in pediatric otorhinolaryngology. Despite its high efficacy in treating obstructive airway disorders, the risk of postoperative complications…
- NEUROLOGICAL COMPLICATIONS IN DIABETICS
Avazova, Nilufar, Rizvonov, Jasur, Tojibayeva, Dildora, Авазова, Нилуфар, Ризвонов, Джасур, Тожибаева, Дилдора, Avazova, Nilufar, Rizvonov, Jasur, Tojibayeva, Dildora · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
This scientific article provides a comprehensive analysis of neurological complications in diabetes mellitus, particularly focusing on diabetic neuropathy. The study systematically examines the clinical manifestations…
- ASSESSMENT OF PREDIABETES PREVALENCE AMONG RURAL AND URBAN POPULATIONS OF ANDIJAN
Yusupova, Shahnoza, Nishanova, Malika, Юсупова, Шахноза, Нишанова, Малика, Yusupova, Shahnoza, Nishanova, Malika · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Relevance. The global prevalence of diabetes mellitus (DM) and prediabetes is steadily increasing, taking on the characteristics of a pandemic. About 90% of all diabetes cases are type 2 diabetes (T2DM), the rise of…
- TIC EPILEPSY IN THE UZBEK POPULATION: CLINICAL AND ENCEPHALOGRAPHIC ASPECTS (PILOT STUDY)
Nurmatova, Dilorom, Sayfitdinhuzhaev, Zainutdinhuzha, Okhunboev, Zhakhongir, Нурматова, Дилором, Сайфитдинхужаев, Зайнутдинхужа, Охунбоев, Жахонгир, Nurmatova, Dilorom, Sayfitdinxo · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Relevance. Tic disorders in children are one of the most common forms of hyperkinesis in pediatric neurological practice, demonstrating a high incidence of comorbidity with various neuropsychiatric and neurological…
- ON THE SIGNIFICANCE OF THE SCORE-2 RISK SCALE FOR CARDIOVASCULAR COMPLICATIONS AMONG PATIENTS WITH PREDIABETES
Yusupova, Shakhnoza, Abdurahmanova, Ruhsorakhon, Юсупова, Шахноза, Абдурахманова, Рухсорахон, Yusupova, Shaxnoza, Abduraxmonova, Ruxsoraxon · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
The aim of the study is to consider and evaluate the value of the SCORE-2 cardiovascular risk scale among patients with prediabetes. Material and methods of the study. The study included 45 people aged 40 to 65 years…
- EFFICACY OF EVEROLIMUS IN COMBINATION WITH LETROZOLE, MEGESTROL ACETATE, AND PACLITAXEL FOR RECURRENT ENDOMETRIAL CANCER
Kamishov, Sergey, Niyozova, Shakhnoza, Isroilbekova, Kamila, Kobilov, Odiljon, Balenkov, Oleg, Камышов, Сергей, Ниёзова, Шахноза, Израильбекова, Камила, Кобилов, Одилжон, Баленков, · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Introduction. Everolimus, an mTOR inhibitor, has already demonstrated efficacy in endometrial cancer, but experience with its use in Uzbekistan is limited. Resistance to standard therapy often develops in…
- MENTAL DISORDERS IN PATIENTS WITH NEWLY DIAGNOSIS OF TUBERCULOSIS
Mamatova, Nargiza, Ashurov, Abduvaliy, Abdukhakimov, Bakhrombek, Маматова, Наргиза, Ашуров, Абдувалий, Абдухакимов, Бахромбек, Mamatova, Nargiza, Ashurov, Abduvaliy, Abduhakimov, B · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Relevance. The problem of tuberculosis, as an infectious disease, does not lose its heart against the background of a widespread decrease in tuberculosis. The results of the study indicate the development of borderline…
- ANALYSIS OF THE CARDIOVASCULAR SYSTEM CONDITION IN PATIENTS WITH CHRONIC KIDNEY DISEASE IN THE SAMARKAND REGION
Mukhitdinova, Gulshon, Мухитдинова, Гулшан, Muxitdinova, Gulshon · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Chronic kidney disease (CKD) is a serious issue in modern healthcare. Numerous studies conducted over the past ten years have shown that the likelihood of cardiovascular diseases (CVD) increases even with a slight…
- THE IMPORTANCE OF MODERN DIGITALIZATION IN MONITORING WOMEN WHO ARE LABOR MIGRANTS WITH HIV INFECTION
Каlniyazova, Inobatkhon, Rakhmanova, Jamila, Калниязова, Инобатхон, Рахманова, Жамила, Каlniyazova, Inobatxon, Raxmanova, Jamila · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Relevance: Currently, the role of mobile population groups in preventing the spread of HIV infection among labor migrants is being increasingly studied. Global migration poses a number of challenges for mobile…
- CLINICO-MOLECULAR CHARACTERISTICS AND THERAPEUTIC STRATEGIES FOR LOCORREGIONAL RECURRENCE OF BREAST CANCER AFTER SURGICAL INTERVENTION
Djurayev, Mirjalol, Zaripova, Parvina, Джураев, Миржалол, Зарипова, Парвина, Jo‘rayev, Mirjalol, Zaripova, Parvina · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Relevance. Breast cancer remains one of the most common and socially significant malignancies among women. Given the high frequency of mastectomies, the risk of locoregional recurrences remains substantial…
- LOCOREGIONAL RECURRENCE OF BREAST CANCER AFTER RADICAL MASTECTOMY: RISK FACTORS, DIAGNOSIS, AND REGIONAL MANAGEMENT STRATEGIES
Djurayev, Mirjalol, Zaripova, Parvina, Джураев, Миржалол, Зарипова, Парвина, Jo‘rayev, Mirjalol, Zaripova, Parvina · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
Relevance. Locoregional recurrence (LRR) of breast cancer (BC) following radical mastectomy presents a significant clinical challenge and is associated with reduced survival. Objective. To assess the risk factors for…
- CHARACTERISTICS OF ADRENAL GLAND PATHOMORPHOLOGY IN MATERNAL DEATH
Shokirov, Khumoyunmirzo, Mamataliyeva, Mavlyuda, Шокиров, Хумоюнмирзо, Маматалиева, Мавлюда, Shokirov, Xumoyunmirzo, Mamataliyeva, Mavlyuda · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-06-28
The relevance of the problem. Maternal mortality is a pressing problem in the world, and although what is being done has a certain result, it is observed at a high level. The purpose of the study was to investigate…
- FREQUENTLY ILL CHILDREN WITH URATE NEPHROPATHY AND THEIR SOCIAL CHARACTERISTICS
Karimova, Barno, Otajonov, Ilkhom, Avezova, Guloyim, Каримова, Барно, Отажонов, Илхом, Авезова, Гулойим, Karimova, Barno, Otajonov, Ilkhom, Avezova, Guloyim · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
The purpose of the study. Determining the share of children with uric nephropathy in the structure of frequently ill children, and studying their social characteristics. Material and research methods. Scientific…
- OPTIMIZATION OF NEPHROGENIC SEPSIS REHABILITATION IN CHILDREN
Karimdjanov, Ilxamjan, Dinmukhamadieva, Dilorom, Xoltayeva, Fotima, Tursunbayev, Anvar, Каримджанов, Илхамджан, Динмухаммадиева, Дилором, Холтаева, Фотима, Турсунбаев, Анвар, Karim · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Relevance. This retrospective study involved the examination of 34 children aged 7 to 14 years suffering from nephrogenic sepsis. Detailed anamnesis data were collected, including physical development indicators…
- PATHOGENESIS AND MOLECULAR-GENETIC ASPECTS OF SALIVARY GLAND TUMORS
Rizaev, Jasur, Akhrorov, Alisher, Ризаев, Жасур, Ахроров, Алишер, Rizayev, Jasur, Akhrorov, Alisher · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
This article analyzes the molecular-genetic mechanisms underlying the development of salivary gland tumors. Key genetic mutations (PLAG1, HMGA2, CTNNB1) and their impact on tumor growth are examined. The role of…
- INHIBIN A AS A PREDICTOR OF RECURRENT PREGNANCY LOSS IN WOMEN WITH HYPERPROLACTINEMIA
Mukhammedaminova, Diyora, Nasirova, Khurshidakhon, Mirzaeva, Umida, Maksudova, Dilafruzkhon, Мухаммедаминова, Диёра, Насырова, Хуршидахон, Мирзаева, Умида, Максудова, Дилафруз, Mux · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Background. Recurrent pregnancy loss (RPL) remains a significant challenge in obstetric practice, impacting the physical and psychological well-being of affected women. Hyperprolactinemia, a common endocrine disorder…
- INFLUENCE OF MULTIPLE UTERINE FIBROIDS AND DERMOD CYST ON UNFAVORABLE PREGNANCY OUTCOME (case report)
Mamatkulova, Mokhegul, Маматкулова, Мохигул, Mamatkulova, Moxigul · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Relevance. The prevalence of uterine fibroids during pregnancy, reported in some studies, ranges from 1.6 to 16.7%, varying from one trimester to another. Ovarian tumors during pregnancy occur in 0.1-3.4% of women. Due…
- MICROELEMENTS AND THEIR IMPORTANCE FOR THE CHILD'S BODY WITH HEMOLYTIC DISEASE OF THE NEWBORNS (literature review)
Arzikulov, Abduraim, Abdullaeva, Gulazzam, Arzibekov, Abdikadir, Арзикулов, Абдурайим, Абдуллаева, Гулаззам, Арзибеков, Абдикадир, Arziqulov, Abduraim, Abdullaeva, Gulazzam, Arzibe · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
This article is devoted to the study of the role of microelementoses in newborns with HDN. To date, the influence of the balance of essential ME on the adaptation capabilities of children in the physiological course of…
- PATHOMORPHOLOGY OF CHANGES IN ALVEOLAR STRUCTURES OF THE LUNGS IN PNEUMOPATHIES AT DIFFERENT PERIODS OF GESTATION
Abdullayeva, Nurzhakhon, Mamatalieva, Mavlyuda, Абдуллаева, Нуржахон, Маматалиева, Мавлюда, Abdullayeva, Nurjahon, Mamataliyeva, Mavlyuda · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Pathomorphological changes in the alveolar structures of the lungs of fetuses and newborn infants who died from various forms of pneumopathy were noted at 22-28 weeks of gestation: total atelectasis, diapedetic…
- EPIDEMIOLOGY OF TESTICULAR CANCER
Jalolov, Oybek, Mamarasulova, Dilfuzakhon, Жалолов, Ойбек, Мамарасулова, Дилфузахон, Jalolov, Oybek, Mamarasulova, Dilfuzahon · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
This review article, devoted to the study of the epidemiology of testicular tumors, presents the analysis of global statistics on oncological diseases, collected from the materials of the World Health Organization…
- FEATURES OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH COMBINED PATHOLOGY OF BRONCHIAL ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Nasirova, Aziza, Насирова, Азиза, Nasirova, Aziza · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Introduction. Mortality from respiratory infections (ARI) has always been high, and is included in the list of the 10 leading causes of death of the world's population according to the World Health Organization[1,9,10]…
- NORMALNYE HISTOSTRUKTURNYE KOMPONENTY BRONCHIALNOY STENKI
Djuraev, Abdulatif, Khamidova, Farida, Ismailov, Jasur, Джураев, Абдулатиф, Хамидова, Фарида, Исмоилов, Жасур, Djuraev, Abdulatif, Xamidova, Farida, Ismoilov, Jasur · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Relevance: The purpose of choosing this topic is related to the need to study the cellular structures of the respiratory epithelium. The mucous membrane of the respiratory tract consists of a complex system of cells…
- COURSE AND DIAGNOSIS OF ACUTE PANCREATITIS IN CHILDREN
Ibatova, Shoira, Ибатова, Шоира, Ibatova, Shoira · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Relevance. Acute pancreatitis is one of the most severe diseases of the digestive system and if not diagnosed in time, complications may develop. The aim of the study. To determine the diagnostic criteria for acute…
- THE PREVALENCE OF ATOPIC DERMATITIS AMONG CHILDREN IN SAMARKAND REGION
Tolibov, Mansur, Толибов, Мансур, Tolibov, Mansur · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases among children. This article presents the results of a retrospective study on the prevalence of AD among children in the Samarkand…
- LARYNGOPHARYNGEAL REFLUX AND ITS RELATIONSHIP WITH CHRONIC HYPERPLASTIC LARYNGITIS
Khushvakova, Nilufar, Khamidova, Farida, Burieva, Dilnoza, Хушвакова, Нилуфар, Хамидова, Фарида, Буриева, Дилноза, Xushvakova, Nilufar, Xamidova, Farida, Burieva, Dilnoza · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Relevance. Chronic hyperplastic laryngitis (CHL) is one of the most common pathologies of the larynx, affecting up to 10% of patients with ENT diseases. In 5% of cases, it precedes the development of laryngeal cancer…
- EPIDEMIOLOGY AND GENETIC ASPECTS OF CYSTIC FIBROSIS (LITERATURE REVIEW)
Khamidova, Farida, Khamraev, Bekzod, Ismoilov, Jasur, Хамидова, Фарида, Хамраев, Бекзод, Исмоилов, Жасур, Xamidova, Farida, Xamraev, Bekzod, Ismoilov, Jasur · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Relevance. Cystic fibrosis (CF), also known as mucoviscidosis or Landsteiner-Fanconi disease, is an autosomal recessive hereditary disorder characterized by systemic damage to the exocrine glands. It manifests as…
- FEATURES OF THE CLINICAL COURSE OF RHEUMATOID ARTHRITIS AT DIFFERENT STAGES OF ITS DEVELOPMENT
Iskandarova, Farida, Искандарова, Фарида, Iskandarova, Farida · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Relevance. Despite great advances in the diagnosis and treatment of rheumatoid arthritis (RA), which have led to a significant improvement in the prognosis of many patients, the fundamental medical problems of this…
- CLINICAL-INSTRUMENTAL STUDY OF THE CARDIOVASCULAR SYSTEM STATUS IN CHILDREN WITH BRONCHIAL ASTHMA
Tolipova, Noila, Latipova, Shakhnoza, Толипова, Ноила, Латипова, Шахноза, Tolipova, Noila, Latipova, Shaxnoza · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Aim of the study: To investigate the state of the cardiovascular system in children with bronchial asthma based on clinical and instrumental research data. Materials and methods: To achieve this goal, a study was…
- PRECINCTION, ETIOLOGY, PATHOGENESIS OF ORAL DISEASES IN PATIENTS ON HEMODIALYSIS
Khabibova, Nazira, Olimova, Dildora, Хабибова, Назира, Олимова, Дилдора, Xabibova, Nazira, Olimova, Dildora · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Introduction: Hemodialysis (HD) is one of the primary treatment methods for patients with end-stage renal disease. While this procedure aims to improve patients' quality of life, long-term hemodialysis may lead to…
- АSSЕSSМЕNТ ОF ТHЕ CОMBINАТIОN ОF QUАNTITАTIVЕ АND QUАLITАTIVЕ SIGNS IN NЕPHRОTIC SYNDRОMЕ IN CHILDRЕN WITH АTОPIC DЕRMАTITIS
Rаkhmаnоvа, Lоlа, Kаrimоvа, Umidа, Sоdikоvа, Nоzimа, Рахманова, Лола, Каримова, Умида, Cадикова, Нозима, Rахmаnоvа, Lоlа, Kаrimоvа, Umidа, Sоdikоvа, Nоzimа · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Rеlеvаncе. Tоdаy, thе cоmоrbid cоursе оf nеphrоtic syndrоmе (NS) аnd аtоpic dеrmаtitis (АD) is оftеn thе cаusе оf еаrly disаbility dеvеlоpmеnt аnd dеаth duе tо thе yеаr-by-yеаr incrеаsе оf chrоnic kidnеy fаilurе аmоng…
- ASSOCIATION OF THE PRO72ARG (RS1042522) POLYMORPHISM OF THE TP53 GENE WITH THE DEVELOPMENT OF MYELOPROLIFERA-TIVE NEOPLASMS IN THE KHOREZM REGION
Zhumaboeva, Marguba, Boboev, Kodirjon, Matmurodov, Rustambek, Zhumanazarova, Shahzoda, Жумабоева, Марғуба, Бобоев, Кодиржон, Матмуродов, Рустамбек, Жуманазарова, Шахзода, Jumaboeva · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Objective: To evaluate the impact of allele and genotype variants of the Pro72Arg (rs1042522) polymorphism of the TP53 gene on the development of myeloproliferative neoplasms (MPNs). Materials and methods: The study…
- NEW OPPORTUNITIES FOR STUDYING THE FUNCTION OF EXTERNAL RESPIRATORY IN CHILDREN
Tashmatova, Gulnoza, Ташматова, Гулноза, Tashmatova, Gulnoza · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
This article is devoted to such a topical problem of social medicine as asthma and allergy in children, which has important theoretical and practical significance. The aim of the work is to evaluate the diagnostic…
- EVALUATION OF THE CLINICAL EFFECTIVENESS OF DIFFERENT METHODS OF ALLERGEN-SPECIFIC IMMUNOTHERAPY IN THE TREATMENT AND PREVENTION OF ALLERGIC DISEASES (BASED ON ADVANCED RESEARCH REVIEW)
Saidxonova, Adibaxon, Mirrakhimova, Maktuba, Саидхонова, Адибахон, Миррахимова, Мактуба, Saidhonova, Adibakhon, Mirraximova, Maktuba · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
The most effective method of treating allergic diseases is allergen-specific immunotherapy (ASIT), which consists in introducing small doses of the antigen responsible for the development of the disease into patients…
- RISK FACTORS AND CLINICAL FEATURES OF COMORBID ATOPIC DERMATITIS IN CHILDREN
Mirrakhimova, Maktuba, Nishanbaeva, Nilufar, Миррахимова, Мактуба, Нишонбаева, Нилуфар, Mirraximova, Maktuba, Nishonboeva, Nilufar · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
Atopic dermatitis is a multifactorial disease caused by the combined effects of genetic changes and trigger mechanisms in the body. It is known that the etiopathogenetic "basis" of multifactorial diseases is the…
- OPTIMIZATION OF THE TREATMENT OF ATOPIC DERMATITIS IN CHILDREN WITH ZINC DEFICIENCY
Mirrahimova, Maktuba, Abidova, Dildora, Миррахимова, Мактуба, Абидова, Дилдора, Mirrahimova, Maktuba, Abidova, Dildora · Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-04-30
The aim of the study was to evaluate the clinical significance of zinc deficiency in children with atopic dermatitis and its correction. Materials and Methods: The study was conducted at the multidisciplinary clinic of…