Clinical characteristics of antibiotic-associated diarrhe in early childhood

Shavdirova, Gulbonu, Шавдирова, Гулбону, Shavdirova, Gulbonu

Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-yil

Annotatsiya

Objective. To determine the clinical features of antibiotic-associated diarrhea (AAD) in young children, to compare differences between infectious and non-infectious forms, and to assess patterns of fever response, dehydration, and the distribution of key symptoms. Materials and Methods. A total of 140 children aged 1 month to 3 years, hospitalized with clinically confirmed AAD following antibacterial therapy, were analyzed at the Samarkand State Medical University and the Samarkand Multidisciplinary Medical Children’s Center during 2023–2025. Results. Higher body temperatures (38–39 °C and >39 °C) were more frequent in infectious forms. In the Cl.difficile (Cl+) group, meteorism (82.3%), loss of appetite (67.7%), and abdominal pain (53.2%) predominated. In the non-infectious form, mild to moderate dehydration was more frequently observed. Conclusion. AAD in early childhood varies depending on its etiology: infectious forms are associated with a stronger inflammatory response, while the Cl+ phenotype has distinctive clinical indicators. In contrast, non-infectious forms are characterized predominantly by mild to moderate dehydration.

Maqola ma’lumotlari
MualliflarShavdirova, Gulbonu, Шавдирова, Гулбону, Shavdirova, Gulbonu
JurnalMedical science of Uzbekistan / O'zbekiston tibbiyot ilmi
NashriyotАндижон давлат тиббиёт институти
ISSN2181-3612
Nashr sanasi2025-10-25
Jild4
Son5
Betlar04-09
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-3612-2025-5-04-09
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-3612-2025-5-04-09 · Maqolaning asl sahifasi

Kalit so‘zlar

antibiotic-associated diarrhea, young children, Cl.difficile, dehydration, clinical features, антибиотик-ассоциированная диарея, дети раннего возраста, Cl.difficile, дегидратация, клинические особенности, antibiotik bilan bog‘liq diareya, erta yoshdagi bolalar, Cl.difficile, degidratatsiya, klinik xususiyatlar

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAShavdirova, Gulbonu, Шавдирова, Гулбону, & Shavdirova, Gulbonu (2025). CLINICAL CHARACTERISTICS OF ANTIBIOTIC-ASSOCIATED DIARRHE IN EARLY CHILDHOOD. Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(5), 04-09. https://doi.org/10.56121/2181-3612-2025-5-04-09
GOST (OAK)Shavdirova, Gulbonu, Шавдирова, Гулбону, Shavdirova, Gulbonu CLINICAL CHARACTERISTICS OF ANTIBIOTIC-ASSOCIATED DIARRHE IN EARLY CHILDHOOD // Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi. – 2025. – T. 4, № 5. – P. 04-09. – DOI: 10.56121/2181-3612-2025-5-04-09.
MLAShavdirova, Gulbonu, Шавдирова, Гулбону, and Shavdirova, Gulbonu. “CLINICAL CHARACTERISTICS OF ANTIBIOTIC-ASSOCIATED DIARRHE IN EARLY CHILDHOOD.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(5), 04-09, 2025. https://doi.org/10.56121/2181-3612-2025-5-04-09
ChicagoShavdirova, Gulbonu, Шавдирова, Гулбону, and Shavdirova, Gulbonu. “CLINICAL CHARACTERISTICS OF ANTIBIOTIC-ASSOCIATED DIARRHE IN EARLY CHILDHOOD.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(5), 04-09 (2025). https://doi.org/10.56121/2181-3612-2025-5-04-09
HarvardShavdirova, Gulbonu, Шавдирова, Гулбону, and Shavdirova, Gulbonu (2025) ‘CLINICAL CHARACTERISTICS OF ANTIBIOTIC-ASSOCIATED DIARRHE IN EARLY CHILDHOOD’, Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(5), 04-09. https://doi.org/10.56121/2181-3612-2025-5-04-09
BibTeX
@article{shavdirovagulbonu2025,
  title = {CLINICAL CHARACTERISTICS OF ANTIBIOTIC-ASSOCIATED DIARRHE IN EARLY CHILDHOOD},
  author = {Shavdirova, Gulbonu and Шавдирова, Гулбону and Shavdirova, Gulbonu},
  journal = {Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi},
  year = {2025},
  volume = {4},
  number = {5},
  pages = {04-09},
  doi = {10.56121/2181-3612-2025-5-04-09},
  url = {https://doi.org/10.56121/2181-3612-2025-5-04-09}
}

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