Features of endothelial dysfunction in patients with combined pathology of bronchial asthma and chronic obstructive pulmonary disease

Nasirova, Aziza, Насирова, Азиза, Nasirova, Aziza

Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi · 2025-yil

Annotatsiya

Introduction. Mortality from respiratory infections (ARI) has always been high, and is included in the list of the 10 leading causes of death of the world's population according to the World Health Organization[1,9,10]. Bronchial asthma (BA) and chronic obstructive pulmonary disease (COPD) are pathologies of the respiratory tract characterized by chronic bronchial obstruction. Both diseases occur due to the interactions of environmental factors and the human body, which lead to a wide range of clinical manifestations. The aim of the study was to evaluate the role of nitric oxide metabolites in the formation of endothelial dysfunction in patients with bronchial asthma, chronic obstructive pulmonary disease and their combination. Research materials and methods: 115 patients and 20 healthy volunteers were examined at the Department of Pulmonology and Allergology of the Samarkand City Medical Association. Results and conclusions. To identify endothelial dysfunction, we studied the ratio of NO2 and NO3 indicators both in the composition of the CV and in the blood. The results showed that patients with COPD +ASTHMA had increased concentrations of NO2 and NO3 compared with the isolated course of the disease (P<0.05; P<0.001) both in the acute and remission stages, which confirmed a high level of endothelial system dysfunction in the combined course of the disease.

Maqola ma’lumotlari
MualliflarNasirova, Aziza, Насирова, Азиза, Nasirova, Aziza
JurnalMedical science of Uzbekistan / O'zbekiston tibbiyot ilmi
NashriyotАндижон давлат тиббиёт институти
ISSN2181-3612
Nashr sanasi2025-04-30
Jild4
Son2
Betlar116-119
TilIngliz
Ilmiy sohaTibbiyot
DOI10.56121/2181-3612-2025-2-116-119
Indeksga qo‘shilgan2026-08-26

DOI: 10.56121/2181-3612-2025-2-116-119 · Maqolaning asl sahifasi

Kalit so‘zlar

respiratory infection, bronchial asthma, chronic obstructive pulmonary disease, exhaled air condensation, респираторная инфекция, бронхиальная астма, хроническая обструктивная болезнь легких, конденсат выдыхаемого воздуха, nafas olish yo'llari infektsiyasi, bronxial astma, surunkali obstruktiv o'pka kasalligi, Chiqarilgan nafas havo kondensati

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APANasirova, Aziza, Насирова, Азиза, & Nasirova, Aziza (2025). FEATURES OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH COMBINED PATHOLOGY OF BRONCHIAL ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE. Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(2), 116-119. https://doi.org/10.56121/2181-3612-2025-2-116-119
GOST (OAK)Nasirova, Aziza, Насирова, Азиза, Nasirova, Aziza FEATURES OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH COMBINED PATHOLOGY OF BRONCHIAL ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE // Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi. – 2025. – T. 4, № 2. – P. 116-119. – DOI: 10.56121/2181-3612-2025-2-116-119.
MLANasirova, Aziza, Насирова, Азиза, and Nasirova, Aziza. “FEATURES OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH COMBINED PATHOLOGY OF BRONCHIAL ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(2), 116-119, 2025. https://doi.org/10.56121/2181-3612-2025-2-116-119
ChicagoNasirova, Aziza, Насирова, Азиза, and Nasirova, Aziza. “FEATURES OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH COMBINED PATHOLOGY OF BRONCHIAL ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE.” Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(2), 116-119 (2025). https://doi.org/10.56121/2181-3612-2025-2-116-119
HarvardNasirova, Aziza, Насирова, Азиза, and Nasirova, Aziza (2025) ‘FEATURES OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH COMBINED PATHOLOGY OF BRONCHIAL ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE’, Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi, 4(2), 116-119. https://doi.org/10.56121/2181-3612-2025-2-116-119
BibTeX
@article{nasirovaaziza2025,
  title = {FEATURES OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH COMBINED PATHOLOGY OF BRONCHIAL ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE},
  author = {Nasirova, Aziza and Насирова, Азиза and Nasirova, Aziza},
  journal = {Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi},
  year = {2025},
  volume = {4},
  number = {2},
  pages = {116-119},
  doi = {10.56121/2181-3612-2025-2-116-119},
  url = {https://doi.org/10.56121/2181-3612-2025-2-116-119}
}

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