Background. Recurrent pregnancy loss (RPL) remains a significant challenge in obstetric practice, impacting the physical and psychological well-being of affected women. Hyperprolactinemia, a common endocrine disorder among women of reproductive age, is associated with an increased risk of early pregnancy loss. Research Objective. To evaluate inhibin A as a biomarker for predicting recurrent pregnancy loss in women suffering from hyperprolactinemia and to highlight its diagnostic significance in early gestation. The article presents a comprehensive review of clinical and experimental findings related to inhibin A secretion dynamics, its role in endocrine regulation, and its diagnostic relevance in early pregnancy complications. The relationship between hyperprolactinemia and impairments in endometrial receptivity, luteal phase function, and hormonal support of early pregnancy is discussed in detail. Additionally, comparative analyses of inhibin A levels in normal versus complicated pregnancies are examined, with attention to its fluctuations across gestational trimesters.
| Mualliflar | Mukhammedaminova, Diyora, Nasirova, Khurshidakhon, Mirzaeva, Umida, Maksudova, Dilafruzkhon, Мухаммедаминова, Диёра, Насырова, Хуршидахон, Мирзаева, Умида, Максудова, Дилафруз, Muxammedaminova, Diyora, Nasirova, Xurshidaxon, Mirzaeva, Umida, Maksudova, Dilafruz |
|---|---|
| Jurnal | Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi |
| Nashr sanasi | 2025-04-30 |
| Jild | 4 |
| Son | 2 |
| Betlar | 149-154 |
| Til | uz_Latn |
| DOI | 10.56121/2181-3612-2025-2-149-154 |
DOI: 10.56121/2181-3612-2025-2-149-154 · Maqolaning asl sahifasi
Inhibin A, hyperprolactinemia, recurrent pregnancy loss, early pregnancy biomarkers, endocrine regulation, miscarriage, pregnancy complications, ингибин А, гиперпролактинемия, привычное невынашивание беременности, биомаркеры ранней беременности, эндокринная регуляция, самопроизвольный аборт, осложнения беременности, ingibin A, giperprolaktinemiya, homilaning takroriy tushishi, erta homiladorlik davri biomarkerlari, endokrin boshqaruv, homilaning o‘z-o‘zidan tushishi, homiladorlik asoratlari
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Medical science of Uzbekistan / O'zbekiston tibbiyot ilmi — barcha maqolalar