Uric acid (hereinafter referred to as UA — Uric Acid) is a metabolite formed through the oxidation of purines and is the main water-soluble antioxidant in the body. Hyperuricemia increases the risk of cardiovascular diseases, including stroke and hypertension, while low UA levels have been observed to reduce its protective effect in neurodegenerative diseases. This review analyzes the biology of UA, its relationship with cardiovascular diseases and aging, as well as its effects in neurodegenerative diseases, based on recent studies. It also examines the role of UA modulators, including allopurinol, febuxostat, and inosine. The conclusion discusses the predominance of the neuroprotective effects of UA and clinical recommendations.
| Mualliflar | Azizov Boburmirzo, Shaxzoda Raximova |
|---|---|
| Jurnal | Ўзбекистон метрологияси |
| Nashriyot | Ўзбекистон техник жиҳатдан тартибга солиш агентлиги |
| ISSN | 2181-3663 |
| Nashr sanasi | 2026-06-25 |
| Jild | 5 |
| Son | 3/S |
| Betlar | 121-132 |
| Til | O‘zbek |
| Ilmiy soha | Texnika |
| DOI | 10.47689/2181-3663-vol5-iss3/s-pp121-132 |
| Indeksga qo‘shilgan | 2026-09-02 |
DOI: 10.47689/2181-3663-vol5-iss3/s-pp121-132 · Maqolaning asl sahifasi · PDF
| APA | Azizov Boburmirzo, & Shaxzoda Raximova (2026). Siydik kislota va neyrodegenerativ kasalliklar: ta’siri va mexanizmlari. Ўзбекистон метрологияси, 5(3/S), 121-132. https://doi.org/10.47689/2181-3663-vol5-iss3/s-pp121-132 |
|---|---|
| GOST (OAK) | Azizov Boburmirzo, Shaxzoda Raximova Siydik kislota va neyrodegenerativ kasalliklar: ta’siri va mexanizmlari // Ўзбекистон метрологияси. – 2026. – T. 5, № 3/S. – B. 121-132. – DOI: 10.47689/2181-3663-vol5-iss3/s-pp121-132. |
| MLA | Azizov Boburmirzo, and Shaxzoda Raximova. “Siydik kislota va neyrodegenerativ kasalliklar: ta’siri va mexanizmlari.” Ўзбекистон метрологияси, 5(3/S), 121-132, 2026. https://doi.org/10.47689/2181-3663-vol5-iss3/s-pp121-132 |
| Chicago | Azizov Boburmirzo, and Shaxzoda Raximova. “Siydik kislota va neyrodegenerativ kasalliklar: ta’siri va mexanizmlari.” Ўзбекистон метрологияси, 5(3/S), 121-132 (2026). https://doi.org/10.47689/2181-3663-vol5-iss3/s-pp121-132 |
| Harvard | Azizov Boburmirzo, and Shaxzoda Raximova (2026) ‘Siydik kislota va neyrodegenerativ kasalliklar: ta’siri va mexanizmlari’, Ўзбекистон метрологияси, 5(3/S), 121-132. https://doi.org/10.47689/2181-3663-vol5-iss3/s-pp121-132 |
| BibTeX | @article{azizovboburmirzo2026,
title = {Siydik kislota va neyrodegenerativ kasalliklar: ta’siri va mexanizmlari},
author = {Azizov Boburmirzo and Shaxzoda Raximova},
journal = {Ўзбекистон метрологияси},
year = {2026},
volume = {5},
number = {3/S},
pages = {121-132},
doi = {10.47689/2181-3663-vol5-iss3/s-pp121-132},
url = {https://doi.org/10.47689/2181-3663-vol5-iss3/s-pp121-132}
} |
Boshqa maqola uchun iqtibos tayyorlash
This article investigates the role of the international BABIES (Birthweight and Age-at-Death Boxes for an Intervention and Evaluation System) and MOMS (Matrix of Mortality and Morbidity Surveillance) charts in reducing…
Due to sarcopenia developing in the setting of chronic obstructive pulmonary disease (COPD), the conventional creatinine marker loses sensitivity in estimating glomerular filtration rate (eGFR). This highlights the need…
In recent years, severe destructive lesions of the upper and lower jaw bones associated with the use of homemade injectable psychoactive substances, including desomorphine, various types of methamphetamine, and other…
The article evaluates the significance of clinical and biochemical parameters in the development of gallstone disease in patients with obesity. The study included patients with obesity and gallstone disease who…
Based on an analysis of scientific literature, this article discusses the prevalence of periodontal tissue diseases among textile industry workers, the occupational and individual risk factors contributing to their…
This article assesses, on the basis of practical and scientific monitoring, the year-by-year expansion of the epizootological and epidemiological ranges of highly dangerous bacterial and viral infectious diseases. Using…
Menstrual cycle disorders are among the most common gynecological problems in adolescent girls and represent an important risk factor for future reproductive health disorders. The aim of this review was to summarize…
Community-acquired pneumonia remains one of the leading causes of morbidity and mortality among children worldwide, while antimicrobial resistance poses an increasing threat to successful clinical treatment. The…
Proximal humerus fractures (PHFs) are among the common injuries of the musculoskeletal system, especially in older age groups. In young patients, they are more often associated with a high-energy mechanism and may be…
Clinical and epidemiological studies show that bronchial obstruction associated with bronchial asthma and chronic obstructive pulmonary disease is widespread among populations of different age groups, while its…
Ўзбекистон метрологияси — barcha maqolalar · 2026-yil arxivi
This article examines compression as a meaning-oriented strategy in sign language translation and interpreting. Compression is understood not as arbitrary shortening, but as the selective reformulation of a source…
This study investigates the impact of Edge Computing on bandwidth utilization in Internet of Things (IoT)–driven Nigerian telecom networks. The rapid growth of IoT devices has significantly increased data traffic…
This article analyzes the scientific, pedagogical, and methodological foundations for the effective integration of national upbringing factors with modern global competencies in the context of continuous education…
This article addresses the problem of improving an adaptive traffic signal control algorithm at urban intersections by taking into account the dynamic characteristics of traffic flow. Fixed-time control under conditions…
Maqolada paxta xomashyosini yirik iflosliklardan tozalash jarayonida arrali baraban va kolosnikli panjara o‘rtasidagi o‘zaro ta’sirni takomillashtirish masalasi ko‘rib chiqilgan. Mavjud tozalagichlarda qo‘llaniladigan…
Maqolada paxta xomashyosini yirik va mayda iflosliklardan tozalash samaradorligini oshirishga qaratilgan ilmiy tadqiqotlar tizimlashtirilib, konstruktiv va texnologik omillarning o‘zaro ta’siri qiyosiy tahlil qilindi…