This article explores the immunotherapeutic significance of the enzyme NTPDase 8 in oncology. In recent years, immunotherapy has emerged as a promising approach in the fight against cancer, highlighting the growing need to understand the complex interactions within the tumor microenvironment (TME). NTPDase 8 belongs to the family of ectonucleotidases involved in the metabolism of extracellular nucleotides and is predominantly expressed in the liver. The article discusses in detail the role of NTPDase 8 in cancer biology, its immunomodulatory functions, and its potential as a therapeutic target in cancer immunotherapy. Additionally, the pharmacological modulation of NTPDase 8 and directions for future research are considered. In conclusion, NTPDase 8 represents a promising target in cancer immunotherapy, and its further investigation may contribute to the development of novel targeted therapeutic strategies
| Mualliflar | Askarov, Ibragim R., Mamatova, Iroda Yu., Tadjibaeva, Mohinur A. |
|---|---|
| Jurnal | Товарлар кимёси ва халқ табобати |
| Nashriyot | Табобат академияси |
| ISSN | 2181-2977 |
| Nashr sanasi | 2025-03-26 |
| Jild | 3 |
| Son | 6 |
| Betlar | 364-380 |
| Til | Ingliz |
| Ilmiy soha | Tibbiyot |
| DOI | 10.55475/jcgtm/vol3.iss6.2024.468 |
| Indeksga qo‘shilgan | 2026-08-26 |
DOI: 10.55475/jcgtm/vol3.iss6.2024.468 · Maqolaning asl sahifasi
NTPDase 8, immunotherapy, oncology, tumor microenvironment, ectonucleotidases, НТФдаза 8, иммунотерапия, онкология, микросреда опухоли, экто-нуклеотидазы, NTPdaza 8, immunoterapiya, onkologiya, oʼsimta mikromuhiti, ektonukleotidazalar
| APA | Askarov, Ibragim R., Mamatova, Iroda Yu., & Tadjibaeva, Mohinur A. (2025). IMMUNOTHERAPEUTIC SIGNIFICANCE OF NTPASE 8 IN ONCOLOGY. Товарлар кимёси ва халқ табобати, 3(6), 364-380. https://doi.org/10.55475/jcgtm/vol3.iss6.2024.468 |
|---|---|
| GOST (OAK) | Askarov, Ibragim R., Mamatova, Iroda Yu., Tadjibaeva, Mohinur A. IMMUNOTHERAPEUTIC SIGNIFICANCE OF NTPASE 8 IN ONCOLOGY // Товарлар кимёси ва халқ табобати. – 2025. – T. 3, № 6. – P. 364-380. – DOI: 10.55475/jcgtm/vol3.iss6.2024.468. |
| MLA | Askarov, Ibragim R., Mamatova, Iroda Yu., and Tadjibaeva, Mohinur A. “IMMUNOTHERAPEUTIC SIGNIFICANCE OF NTPASE 8 IN ONCOLOGY.” Товарлар кимёси ва халқ табобати, 3(6), 364-380, 2025. https://doi.org/10.55475/jcgtm/vol3.iss6.2024.468 |
| Chicago | Askarov, Ibragim R., Mamatova, Iroda Yu., and Tadjibaeva, Mohinur A. “IMMUNOTHERAPEUTIC SIGNIFICANCE OF NTPASE 8 IN ONCOLOGY.” Товарлар кимёси ва халқ табобати, 3(6), 364-380 (2025). https://doi.org/10.55475/jcgtm/vol3.iss6.2024.468 |
| Harvard | Askarov, Ibragim R., Mamatova, Iroda Yu., and Tadjibaeva, Mohinur A (2025) ‘IMMUNOTHERAPEUTIC SIGNIFICANCE OF NTPASE 8 IN ONCOLOGY’, Товарлар кимёси ва халқ табобати, 3(6), 364-380. https://doi.org/10.55475/jcgtm/vol3.iss6.2024.468 |
| BibTeX | @article{askarovibragimr2025,
title = {IMMUNOTHERAPEUTIC SIGNIFICANCE OF NTPASE 8 IN ONCOLOGY},
author = {Askarov, Ibragim R. and Mamatova, Iroda Yu. and Tadjibaeva, Mohinur A.},
journal = {Товарлар кимёси ва халқ табобати},
year = {2025},
volume = {3},
number = {6},
pages = {364-380},
doi = {10.55475/jcgtm/vol3.iss6.2024.468},
url = {https://doi.org/10.55475/jcgtm/vol3.iss6.2024.468}
} |
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