The antiradical activity of an extract obtained from the dried and ground aerial part of the dioecious nettle (Urtica dioica L.) by extraction in 96% ethanol using an ultrasonic bath for 20 minutes was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging method. The quantitative content of phenolic compounds (flavonoids) was determined by high-performance liquid chromatography (HPLC). The resulting extract exhibited antiradical activity, with an IC₅₀ value of 314.64 µL. Chromatographic analysis showed that 100 g of dried Urtica dioica L. contains 7.3 mg of quercetin, 6.4 mg of rutin, 0.7 mg of salicylic acid, and 0.1 mg of apigenin.
| Mualliflar | Abdulloyev, Shakhobiddin Kh., Abdirazokov, Allanazar, Mominova, Nozimakhan I. |
|---|---|
| Jurnal | Товарлар кимёси ва халқ табобати |
| Nashr sanasi | 2025-06-25 |
| Jild | 4 |
| Son | 1 |
| Betlar | 173-191 |
| Til | O‘zbek |
| DOI | 10.55475/jcgtm/vol4.iss1.2025.460 |
DOI: 10.55475/jcgtm/vol4.iss1.2025.460 · Maqolaning asl sahifasi
Urtica dioica L., экстракция, антирадикальная активность, дифенилпикрилгидразил, ВЭЖХ, флавоноид, кверцетин, рутин, Urtica dioica L., extraction, antiradical activity, 2,2-diphenyl-1-picrylhydrazyl, HPLC, flavonoid, quercetin, rutin, Urtica dioica L., ekstraktsiya, antiradikal faollik, difenilpikrilgidrazil, YuSSX, flavanoid, quersetin, rutin
In this work, the role of adenosine receptors A1 in the tumor process and the possibility of its use and the quality of the therapeutic target are analyzed. Receptor A1 plays a key role in the regulation of cell…
This article describes the properties, metabolites of chemical transformations, and the use of Amygdalin in the treatment of oncological diseases. The proposed mechanisms of action of amygdalin on cancer cells, the…
This article explores the immunotherapeutic significance of the enzyme NTPDase 8 in oncology. In recent years, immunotherapy has emerged as a promising approach in the fight against cancer, highlighting the growing need…
In this article, the amount of water-soluble vitamins contained in the Maclura pomifera fruit growing in Uzbekistan was determined and analyzed using the HPLC method. While 7 different vitamins have been studied in…
This article describes Lonicera nummularifolia L. and provides a brief morphological and biological characterization of the plant, as well as its significance in traditional medicine. Lonicera nummularifolia L. was…
This article identifies and analyzes the content of water-soluble vitamins in the fruits of Maclura pomifera growing in Uzbekistan using HPLC. Additionally, a comparison was made with the amounts found in Maclura…
This article provides information about the chemical composition, botanical characteristics, and the role of the Bidens plant in traditional medicine. The content of flavonoids in the dry extract of Bidens was…
This article presents the results of the evaluation of the antiradical activity of the alcoholic extract of potato (Solanum tuberosum L.) leaves by the method of quenching diphenylpicrylhydrazyl (DPPH) free radicals and…
Macrophages play a crucial role in the immune response of the body, including protection against infections and maintaining homeostasis. However, in the context of oncological diseases, macrophages can have both…
The article presents the results of a study of changes in the antioxidant activity of the food supplement "Ascalcium" containing natural biological substances under the influence of laser treatment. According to the…