Gender-specific features of dilated cardiomyopathy in the uzbek population

Абдуллаев , Т, Цой , И, Гуломов , Х, Мирзарахимова, С, Худойберганов , О, Рахматов, М, Abdullayev, Timur, Soy , Igor, Gulomov , Xumoyun, Mirzaraximova, Saodat, Xudoyberganov, Otabek, Raxmatov, Maxmud, Abdullayev, Timur, Soy , Igor, Gulomov , Khumoyun, Mirzarakhimova, Saodat, Khudoyberganov , Otabek, Rakhmatov, Makhmud

O‘zbekiston кardiologiyasi · 2025-yil

Annotatsiya

Dilated cardiomyopathy (DCM) is one of the most common non-ischemic myocardial disease characterized by systolic dysfunction and cardiac chamber dilation. Gender-specific features of DCM progression and prognosis remain understudied. Aim. To evaluate gender-specific characteristics of medical history, clinical presentation, and functional parameters in patients with DCM in the Uzbek population. Materials and methods. A retrospective analysis included 269 DCM patients (180 men, 89 women) treated at the Republican Specialized Scientific-Practical Medical Center of Cardiology from 2010 to 2017. Data on age at diagnosis, disease duration, hospitalizations, NYHA class, hemodynamics, and six-minute walking test were assessed. Statistical analysis involved t-test and χ2 test (p < 0.05). Results. Women were younger at diagnosis (33.7 vs. 41.3 years; p < 0.001), had shorter disease duration (p = 0.041), and were hospitalized more frequently (75% vs. 65%; p = 0.041). No significant differences were found in NYHA class, blood pressure, or respiratory parameters. Men demonstrated better physical endurance (p = 0.191). Conclusion. Significant gender differences were identified, underscoring the need for personalized management of DCM patients.

Maqola ma’lumotlari
MualliflarАбдуллаев , Т, Цой , И, Гуломов , Х, Мирзарахимова, С, Худойберганов , О, Рахматов, М, Abdullayev, Timur, Soy , Igor, Gulomov , Xumoyun, Mirzaraximova, Saodat, Xudoyberganov, Otabek, Raxmatov, Maxmud, Abdullayev, Timur, Soy , Igor, Gulomov , Khumoyun, Mirzarakhimova, Saodat, Khudoyberganov , Otabek, Rakhmatov, Makhmud
JurnalO‘zbekiston кardiologiyasi
Nashr sanasi2025-03-30
Jild2
Son1
Betlar39-45
TilRus
DOI10.70626/cardiouz-2025-2-00036

DOI: 10.70626/cardiouz-2025-2-00036 · Maqolaning asl sahifasi

Kalit so‘zlar

dilated cardiomyopathy, gender differences, retrospective analysis, Uzbek population, dilated kardiyomiyopatiya, genderga xos farqlar, retrospektiv tahlil, O‘zbek populyatsiyasi, дилатационная кардиомиопатия, гендерные различия, ретроспективный анализ, узбекская популяция

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