An integrated approach to determining the risk of developing preeclampsia in pregnant women with hypertensive conditions

Садуллоева, Мохинур, Закирова , Ф, Турсунова , М, Абдухакимов , А, Икрамова , С, Джураева , В, Sadulloeva, Mokhinur, Zakirova , Feruza, Tursunova , Malika, Abdukhakimov , Abror, Ikramova , Saida, Djuraeva, Vasilakhon, Sadulloeva, Moxinur, Zakirova , Feruza, Tursunova , Malika, Abduxakimov , Abror, Ikramova , Saida, Juraeva , Vasilaxon

O‘zbekiston кardiologiyasi · 2025-yil

Annotatsiya

Aim. Hypertensive disorders complicate one in ten pregnancies, which necessitates the development of new standards for determining the risk of preeclampsia and heart failure in pregnant women. To determine early clinical markers in pregnant women with gestational arterial hypertension (GAH) as sensitive diagnostic criteria for the development of hypertensive complications. Materials and methods. The study included 91 pregnant women of the 2nd-3rd trimesters, divided into groups: healthy pregnant women (n=44) and with GAH (n=47) according to the ESC Guidelines 2018. Physical examination, blood pressure measurement, BMI calculation, detailed blood tests including lipidogram, coagulogram, determination of prolactin and NT-proBNP, echocardiography, vascular stress test to assess endothelial function were performed. Results. Pregnant women with GAH were found to have morphofunctional changes in the heart, early signs of endothelial dysfunction, lipid and carbohydrate metabolism disorders. Microalbuminuria demonstrated high diagnostic value for detecting early renal dysfunction. The prognostic significance of prolactin and NT-proBNP levels was established. Conclusion. Comprehensive early monitoring of clinical and biochemical parameters of pregnant women with GAG is necessary for timely detection of preeclampsia predictors. The results contribute to the improvement of diagnostic and preventive standards for the management of this cohort of patients.

Maqola ma’lumotlari
MualliflarСадуллоева, Мохинур, Закирова , Ф, Турсунова , М, Абдухакимов , А, Икрамова , С, Джураева , В, Sadulloeva, Mokhinur, Zakirova , Feruza, Tursunova , Malika, Abdukhakimov , Abror, Ikramova , Saida, Djuraeva, Vasilakhon, Sadulloeva, Moxinur, Zakirova , Feruza, Tursunova , Malika, Abduxakimov , Abror, Ikramova , Saida, Juraeva , Vasilaxon
JurnalO‘zbekiston кardiologiyasi
NashriyotЎзбекистон кардиологлар ассоциацияси
ISSN3060-4850
Nashr sanasi2025-06-30
Jild2
Son2
Betlar99-109
TilIngliz
Ilmiy sohaTibbiyot
DOI10.70626/cardiouz-2025-2-00042
Indeksga qo‘shilgan2026-08-26

DOI: 10.70626/cardiouz-2025-2-00042 · Maqolaning asl sahifasi

Kalit so‘zlar

Артериальная гипертензия, преэклампсия, сердечная недостаточность, материнская смертность, эндотелиальная дисфункция, пролактин, гестационная артериальная гипертензия, arterial hypertension, preeclampsia, heart failure, maternal mortality, endothelial dysfunction, left ventricular hypertrophy, overweight, microalbuminuria, prolactin, brain natriuretic peptide, arterial gipertenziya, preeklampsiya, yurak yetishmovchiligi, onalar o‘limi, endotelial disfunktsiya, chap qorinchani gipertrofiyasi, ortiqcha tana vazni, mikroalbuminuriya, prolaktin, miya natriyuretik peptidi

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAСадуллоева, Мохинур, Закирова , Ф, Турсунова , М, Абдухакимов , А, Икрамова , С, Джураева , В, Sadulloeva, Mokhinur, Zakirova , Feruza, Tursunova , Malika, Abdukhakimov , Abror, Ikramova , Saida, Djuraeva, Vasilakhon, Sadulloeva, Moxinur, Zakirova , Feruza, Tursunova , Malika, Abduxakimov , Abror, Ikramova , Saida, & Juraeva , Vasilaxon (2025). An integrated approach to determining the risk of developing preeclampsia in pregnant women with hypertensive conditions. O‘zbekiston кardiologiyasi, 2(2), 99-109. https://doi.org/10.70626/cardiouz-2025-2-00042
GOST (OAK)Садуллоева, Мохинур va b. An integrated approach to determining the risk of developing preeclampsia in pregnant women with hypertensive conditions // O‘zbekiston кardiologiyasi. – 2025. – T. 2, № 2. – P. 99-109. – DOI: 10.70626/cardiouz-2025-2-00042.
MLAСадуллоева, Мохинур, Закирова , Ф, Турсунова , М, Абдухакимов , А, Икрамова , С, Джураева , В, Sadulloeva, Mokhinur, Zakirova , Feruza, Tursunova , Malika, Abdukhakimov , Abror, Ikramova , Saida, Djuraeva, Vasilakhon, Sadulloeva, Moxinur, Zakirova , Feruza, Tursunova , Malika, Abduxakimov , Abror, Ikramova , Saida, and Juraeva , Vasilaxon. “An integrated approach to determining the risk of developing preeclampsia in pregnant women with hypertensive conditions.” O‘zbekiston кardiologiyasi, 2(2), 99-109, 2025. https://doi.org/10.70626/cardiouz-2025-2-00042
ChicagoСадуллоева, Мохинур, Закирова , Ф, Турсунова , М, Абдухакимов , А, Икрамова , С, Джураева , В, Sadulloeva, Mokhinur, Zakirova , Feruza, Tursunova , Malika, Abdukhakimov , Abror, Ikramova , Saida, Djuraeva, Vasilakhon, Sadulloeva, Moxinur, Zakirova , Feruza, Tursunova , Malika, Abduxakimov , Abror, Ikramova , Saida, and Juraeva , Vasilaxon. “An integrated approach to determining the risk of developing preeclampsia in pregnant women with hypertensive conditions.” O‘zbekiston кardiologiyasi, 2(2), 99-109 (2025). https://doi.org/10.70626/cardiouz-2025-2-00042
HarvardСадуллоева, Мохинур, Закирова , Ф, Турсунова , М, Абдухакимов , А, Икрамова , С, Джураева , В, Sadulloeva, Mokhinur, Zakirova , Feruza, Tursunova , Malika, Abdukhakimov , Abror, Ikramova , Saida, Djuraeva, Vasilakhon, Sadulloeva, Moxinur, Zakirova , Feruza, Tursunova , Malika, Abduxakimov , Abror, Ikramova , Saida, and Juraeva , Vasilaxon (2025) ‘An integrated approach to determining the risk of developing preeclampsia in pregnant women with hypertensive conditions’, O‘zbekiston кardiologiyasi, 2(2), 99-109. https://doi.org/10.70626/cardiouz-2025-2-00042
BibTeX
@article{article2025,
  title = {An integrated approach to determining the risk of developing preeclampsia in pregnant women with hypertensive conditions},
  author = {Садуллоева, Мохинур and Закирова , Ф and Турсунова , М and Абдухакимов , А and Икрамова , С and Джураева , В and Sadulloeva, Mokhinur and Zakirova , Feruza and Tursunova , Malika and Abdukhakimov , Abror and Ikramova , Saida and Djuraeva, Vasilakhon and Sadulloeva, Moxinur and Zakirova , Feruza and Tursunova , Malika and Abduxakimov , Abror and Ikramova , Saida and Juraeva , Vasilaxon},
  journal = {O‘zbekiston кardiologiyasi},
  year = {2025},
  volume = {2},
  number = {2},
  pages = {99-109},
  doi = {10.70626/cardiouz-2025-2-00042},
  url = {https://doi.org/10.70626/cardiouz-2025-2-00042}
}

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