The significance of the triglyceride/high-density lipoprotein cholesterol index as a predictor of major cardiovascular events

Kim, Andrey, Alieva, Rano, Shek, Aleksandr, Kim, A, Алиева, Р, Shek, A, Kim, A, Aliyeva, R, Shek, A

O‘zbekiston кardiologiyasi · 2025-yil

Annotatsiya

Aim. To study the influence of the TG/HDL-C index on the development of major cardiovascular events in patients with coronary artery disease. Materials and methods. The study included 221 patients with a diagnosis of coronary artery disease, progressive angina pectoris, hospitalized in the department of coronary heart disease and dyslipidemia. All patients were determined biochemical parameters and imaging markers. Results. When comparing patients with and without metabolic syndrome, the latter had a higher TG/HDL-C index (p<0.001), as well as CVD (p<0.001). In addition, a 3-year follow-up showed that an increase in TG/HDL-C above a certain point (Yuden index 5.1) with a statistically significant result led to a more frequent development of MACE (p<0.001), revascularization (p<0.05). Based on the results of the study, a multiple logistic regression model was built using 4 significant variables - EFT, Age, Lp(a) and TG/HDL-C. Conclusion. The triglycerides/high-density lipoprotein cholesterol index can serve as an additional criterion in the selection of lipid-lowering therapy to reduce the residual risk, with an increase in which the addition of fenofibrate should be considered.

Maqola ma’lumotlari
MualliflarKim, Andrey, Alieva, Rano, Shek, Aleksandr, Kim, A, Алиева, Р, Shek, A, Kim, A, Aliyeva, R, Shek, A
JurnalO‘zbekiston кardiologiyasi
NashriyotЎзбекистон кардиологлар ассоциацияси
ISSN3060-4850
Nashr sanasi2025-03-30
Jild2
Son1
Betlar29-38
TilIngliz
Ilmiy sohaTibbiyot
DOI10.70626/cardiouz-2025-2-00035
Indeksga qo‘shilgan2026-08-26

DOI: 10.70626/cardiouz-2025-2-00035 · Maqolaning asl sahifasi

Kalit so‘zlar

coronary artery disease, cardiometabolic syndrome, triglycerides, high-density lipoprotein cholesterol, ишемическая болезнь сердца, кардиометаболический синдром, триглицериды, холестерин липопротеидов высокой плотности, yurak ishemik kasalligi, kardiometabolik sindrom, triglitseridlar, yuqori zichlikdagi lipoproteinlar

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAKim, Andrey, Alieva, Rano, Shek, Aleksandr, Kim, A, Алиева, Р, Shek, A, Kim, A, Aliyeva, R, & Shek, A (2025). The significance of the triglyceride/high-density lipoprotein cholesterol index as a predictor of major cardiovascular events. O‘zbekiston кardiologiyasi, 2(1), 29-38. https://doi.org/10.70626/cardiouz-2025-2-00035
GOST (OAK)Kim, Andrey va b. The significance of the triglyceride/high-density lipoprotein cholesterol index as a predictor of major cardiovascular events // O‘zbekiston кardiologiyasi. – 2025. – T. 2, № 1. – P. 29-38. – DOI: 10.70626/cardiouz-2025-2-00035.
MLAKim, Andrey, Alieva, Rano, Shek, Aleksandr, Kim, A, Алиева, Р, Shek, A, Kim, A, Aliyeva, R, and Shek, A. “The significance of the triglyceride/high-density lipoprotein cholesterol index as a predictor of major cardiovascular events.” O‘zbekiston кardiologiyasi, 2(1), 29-38, 2025. https://doi.org/10.70626/cardiouz-2025-2-00035
ChicagoKim, Andrey, Alieva, Rano, Shek, Aleksandr, Kim, A, Алиева, Р, Shek, A, Kim, A, Aliyeva, R, and Shek, A. “The significance of the triglyceride/high-density lipoprotein cholesterol index as a predictor of major cardiovascular events.” O‘zbekiston кardiologiyasi, 2(1), 29-38 (2025). https://doi.org/10.70626/cardiouz-2025-2-00035
HarvardKim, Andrey, Alieva, Rano, Shek, Aleksandr, Kim, A, Алиева, Р, Shek, A, Kim, A, Aliyeva, R, and Shek, A (2025) ‘The significance of the triglyceride/high-density lipoprotein cholesterol index as a predictor of major cardiovascular events’, O‘zbekiston кardiologiyasi, 2(1), 29-38. https://doi.org/10.70626/cardiouz-2025-2-00035
BibTeX
@article{kimandrey2025,
  title = {The significance of the triglyceride/high-density lipoprotein cholesterol index as a predictor of major cardiovascular events},
  author = {Kim, Andrey and Alieva, Rano and Shek, Aleksandr and Kim, A and Алиева, Р and Shek, A and Kim, A and Aliyeva, R and Shek, A},
  journal = {O‘zbekiston кardiologiyasi},
  year = {2025},
  volume = {2},
  number = {1},
  pages = {29-38},
  doi = {10.70626/cardiouz-2025-2-00035},
  url = {https://doi.org/10.70626/cardiouz-2025-2-00035}
}

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