Trends in the management of intracranial meningioma

Ravshanov Davron Mavlonovich

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2026-yil

Annotatsiya

Introduction. Intracranial meningiomas are the most common primary brain tumors and exhibit substantial clinical and biological heterogeneity. Over the last two decades, management paradigms have shifted: alongside surgical resection, stereotactic radiosurgery, fractionated radiotherapy, and active surveillance have gained increasing importance, particularly for small asymptomatic lesions. Materials and Methods. A retrospective analytical review of population-based cohorts and large oncologic registries was performed. Demographics, tumor characteristics (size, WHO grade), clinical status, treatment strategy (observation, surgery, radiotherapy, combined approaches), and survival-related factors were assessed using descriptive statistics, multivariable regression models, and survival analyses. Results. The cohort was predominantly female, and most tumors were WHO grade I. Over time, an increase in active surveillance and a relative decrease in surgical treatment rates were observed, particularly among patients with small tumors. Surgery remained the primary modality for large and symptomatic lesions, whereas radiosurgery and adjuvant radiotherapy were applied selectively, mainly for challenging skull-base locations, subtotal resection, and WHO grade II–III tumors. Older age, higher comorbidity burden, larger tumor size, and higher grade were associated with worse outcomes. Conclusion. Current intracranial meningioma management is increasingly driven by a personalized, multidisciplinary strategy integrating clinical, radiological, and molecular-genetic parameters (within the WHO 2021 framework) to optimize risk stratification, tailor surgical extent, and justify radiotherapy or surveillance.

Maqola ma’lumotlari
MualliflarRavshanov Davron Mavlonovich
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2026-08-05
Jild11
Son3
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

внутричерепная менингиома; нейрохирургия; стереотаксическая радиохирургия; лучевая терапия; активное наблюдение; WHO 2021; молекулярные маркеры; прогноз; выживаемость, intracranial meningioma; neurosurgery; stereotactic radiosurgery; radiotherapy; active surveillance; WHO 2021; molecular markers; prognosis; survival, bosh miya ichidagi meningioma; neyroxirurgiya; stereotaksik radiojarrohlik; nurlanish terapiyasi; faol kuzatuv; WHO 2021; molekulyar markerlar; prognoz; omon qolish

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APARavshanov Davron Mavlonovich (2026). TRENDS IN THE MANAGEMENT OF INTRACRANIAL MENINGIOMA. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(3). https://tadqiqot.uz/index.php/biomedicine/article/view/14738
GOST (OAK)Ravshanov Davron Mavlonovich TRENDS IN THE MANAGEMENT OF INTRACRANIAL MENINGIOMA // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2026. – T. 11, № 3.
MLARavshanov Davron Mavlonovich. “TRENDS IN THE MANAGEMENT OF INTRACRANIAL MENINGIOMA.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(3), 2026. https://tadqiqot.uz/index.php/biomedicine/article/view/14738
ChicagoRavshanov Davron Mavlonovich. “TRENDS IN THE MANAGEMENT OF INTRACRANIAL MENINGIOMA.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(3) (2026). https://tadqiqot.uz/index.php/biomedicine/article/view/14738
HarvardRavshanov Davron Mavlonovich (2026) ‘TRENDS IN THE MANAGEMENT OF INTRACRANIAL MENINGIOMA’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(3). https://tadqiqot.uz/index.php/biomedicine/article/view/14738
BibTeX
@article{ravshanovdavronmavlonovich2026,
  title = {TRENDS IN THE MANAGEMENT OF INTRACRANIAL MENINGIOMA},
  author = {Ravshanov Davron Mavlonovich},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2026},
  volume = {11},
  number = {3},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/14738}
}

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