Optimization of endovascular strategy in acute ischemic stroke considering angioarchitecture and collateral circulation

KILICHEV Farrukh Akhmadovich, YARMUKHAMEDOVA Nargiza Anvarovna, ALIEV Mansur Abdukholikovich

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2026-yil

Annotatsiya

Acute ischemic stroke remains a leading cause of mortality and long-term disability worldwide despite significant advances in reperfusion therapy. Modern endovascular treatment, particularly mechanical thrombectomy, has demonstrated high efficacy in restoring blood flow in large vessel occlusions. However, clinical outcomes remain heterogeneous, reflecting the complex interaction between vascular angioarchitecture, thrombus characteristics, and collateral circulation status. Aim of the study. To evaluate the impact of angioarchitecture and collateral status on endovascular treatment outcomes and to develop an optimized algorithm for selecting thrombectomy techniques. A prospective cohort study was conducted including 148 patients with acute ischemic stroke who underwent multimodal imaging assessment, including CT, CTA, and CTP, followed by stratification according to the intervention strategy. Results. Algorithm-based approach incorporating collateral circulation and vascular anatomy significantly increased the rate of complete reperfusion (mTICI 3), improved the likelihood of achieving the First Pass Effect, and enhanced functional outcomes at 90 days. Favorable collateral status was associated with reduced infarct growth and a higher probability of functional independence.

Maqola ma’lumotlari
MualliflarKILICHEV Farrukh Akhmadovich, YARMUKHAMEDOVA Nargiza Anvarovna, ALIEV Mansur Abdukholikovich
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2026-08-05
Jild11
Son3
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

ишемический инсульт, механическая тромбэктомия, коллатеральное кровообращение, ангиоархитектоника, эндоваскулярная терапия, реперфузия, mTICI, First Pass Effect, CTA, CTP, ischemic stroke, mechanical thrombectomy, collateral circulation, angioarchitecture, endovascular therapy, reperfusion, mTICI, First Pass Effect, CTA, CTP, ishemik insult, mexanik trombektomiya, kollateral qon aylanishi, angioarxitektonika, endovaskulyar terapiya, reperfuziya, mTICI, First Pass Effect, KTA, KTP

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAKILICHEV Farrukh Akhmadovich, YARMUKHAMEDOVA Nargiza Anvarovna, & ALIEV Mansur Abdukholikovich (2026). OPTIMIZATION OF ENDOVASCULAR STRATEGY IN ACUTE ISCHEMIC STROKE CONSIDERING ANGIOARCHITECTURE AND COLLATERAL CIRCULATION. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(3). https://tadqiqot.uz/index.php/biomedicine/article/view/14740
GOST (OAK)KILICHEV Farrukh Akhmadovich, YARMUKHAMEDOVA Nargiza Anvarovna, ALIEV Mansur Abdukholikovich OPTIMIZATION OF ENDOVASCULAR STRATEGY IN ACUTE ISCHEMIC STROKE CONSIDERING ANGIOARCHITECTURE AND COLLATERAL CIRCULATION // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2026. – T. 11, № 3.
MLAKILICHEV Farrukh Akhmadovich, YARMUKHAMEDOVA Nargiza Anvarovna, and ALIEV Mansur Abdukholikovich. “OPTIMIZATION OF ENDOVASCULAR STRATEGY IN ACUTE ISCHEMIC STROKE CONSIDERING ANGIOARCHITECTURE AND COLLATERAL CIRCULATION.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(3), 2026. https://tadqiqot.uz/index.php/biomedicine/article/view/14740
ChicagoKILICHEV Farrukh Akhmadovich, YARMUKHAMEDOVA Nargiza Anvarovna, and ALIEV Mansur Abdukholikovich. “OPTIMIZATION OF ENDOVASCULAR STRATEGY IN ACUTE ISCHEMIC STROKE CONSIDERING ANGIOARCHITECTURE AND COLLATERAL CIRCULATION.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(3) (2026). https://tadqiqot.uz/index.php/biomedicine/article/view/14740
HarvardKILICHEV Farrukh Akhmadovich, YARMUKHAMEDOVA Nargiza Anvarovna, and ALIEV Mansur Abdukholikovich (2026) ‘OPTIMIZATION OF ENDOVASCULAR STRATEGY IN ACUTE ISCHEMIC STROKE CONSIDERING ANGIOARCHITECTURE AND COLLATERAL CIRCULATION’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(3). https://tadqiqot.uz/index.php/biomedicine/article/view/14740
BibTeX
@article{kilichevfarrukhakhmadovich2026,
  title = {OPTIMIZATION OF ENDOVASCULAR STRATEGY IN ACUTE ISCHEMIC STROKE CONSIDERING ANGIOARCHITECTURE AND COLLATERAL CIRCULATION},
  author = {KILICHEV Farrukh Akhmadovich and YARMUKHAMEDOVA Nargiza Anvarovna and ALIEV Mansur Abdukholikovich},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2026},
  volume = {11},
  number = {3},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/14740}
}

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