Dynamics of changes in the concentration of bone tissue destruction markers and pH level in the oral fluid of patients with oncopathology during chemoradiotherapy

SHARIPOV Khurshed Saidjonovich, RIZAEV Jasur Alimjanovich, ASHUROV Gayur Gafurovich

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2026-yil

Annotatsiya

The spectrum of dental diseases during chemoradiotherapy includes mucositis of varying severity, xerostomia, caries, periodontitis, fungal infections, and other pathological conditions. The mechanisms for the development of these complications are multifactorial and are related to both the direct cytotoxic effect of chemotherapy drugs and ionizing radiation on the oral mucosa, as well as to secondary effects, including disruption of the microbiocenosis, decreased local immunity, and changes in the composition and properties of saliva. Despite the high clinical and social significance of this problem, the issues of prevention, diagnosis, and treatment of dental diseases in oncology patients remain insufficiently studied and require a further systematic approach.

Maqola ma’lumotlari
MualliflarSHARIPOV Khurshed Saidjonovich, RIZAEV Jasur Alimjanovich, ASHUROV Gayur Gafurovich
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2026-08-05
Jild11
Son3
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

химиолучевая терапия, оральный мукозит, биохимические маркеры, ММР-8, остеопонтин, эластаза, антиоксидантно-прооксидантный индекс, остеорадионекроз, ротовая жидкость, онкостоматология, chemoradiotherapy, oral mucositis, biochemical markers, MMP-8, osteopontin, elastase, antioxidant-prooxidant index, osteoradionecrosis, oral fluid, oncostomatology, kimyonur terapiyasi, oral mukozit, biokimyoviy markerlar, MMP-8, osteopontin, elastaza, antioksidant-prooksidant indeksi, osteoradionekroz, og‘iz suyuqligi, onkostomatologiya

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APASHARIPOV Khurshed Saidjonovich, RIZAEV Jasur Alimjanovich, & ASHUROV Gayur Gafurovich (2026). DYNAMICS OF CHANGES IN THE CONCENTRATION OF BONE TISSUE DESTRUCTION MARKERS AND PH LEVEL IN THE ORAL FLUID OF PATIENTS WITH ONCOPATHOLOGY DURING CHEMORADIOTHERAPY. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(3). https://tadqiqot.uz/index.php/biomedicine/article/view/14746
GOST (OAK)SHARIPOV Khurshed Saidjonovich, RIZAEV Jasur Alimjanovich, ASHUROV Gayur Gafurovich DYNAMICS OF CHANGES IN THE CONCENTRATION OF BONE TISSUE DESTRUCTION MARKERS AND PH LEVEL IN THE ORAL FLUID OF PATIENTS WITH ONCOPATHOLOGY DURING CHEMORADIOTHERAPY // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2026. – T. 11, № 3.
MLASHARIPOV Khurshed Saidjonovich, RIZAEV Jasur Alimjanovich, and ASHUROV Gayur Gafurovich. “DYNAMICS OF CHANGES IN THE CONCENTRATION OF BONE TISSUE DESTRUCTION MARKERS AND PH LEVEL IN THE ORAL FLUID OF PATIENTS WITH ONCOPATHOLOGY DURING CHEMORADIOTHERAPY.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(3), 2026. https://tadqiqot.uz/index.php/biomedicine/article/view/14746
ChicagoSHARIPOV Khurshed Saidjonovich, RIZAEV Jasur Alimjanovich, and ASHUROV Gayur Gafurovich. “DYNAMICS OF CHANGES IN THE CONCENTRATION OF BONE TISSUE DESTRUCTION MARKERS AND PH LEVEL IN THE ORAL FLUID OF PATIENTS WITH ONCOPATHOLOGY DURING CHEMORADIOTHERAPY.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(3) (2026). https://tadqiqot.uz/index.php/biomedicine/article/view/14746
HarvardSHARIPOV Khurshed Saidjonovich, RIZAEV Jasur Alimjanovich, and ASHUROV Gayur Gafurovich (2026) ‘DYNAMICS OF CHANGES IN THE CONCENTRATION OF BONE TISSUE DESTRUCTION MARKERS AND PH LEVEL IN THE ORAL FLUID OF PATIENTS WITH ONCOPATHOLOGY DURING CHEMORADIOTHERAPY’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 11(3). https://tadqiqot.uz/index.php/biomedicine/article/view/14746
BibTeX
@article{sharipovkhurshedsaidjonovich2026,
  title = {DYNAMICS OF CHANGES IN THE CONCENTRATION OF BONE TISSUE DESTRUCTION MARKERS AND PH LEVEL IN THE ORAL FLUID OF PATIENTS WITH ONCOPATHOLOGY DURING CHEMORADIOTHERAPY},
  author = {SHARIPOV Khurshed Saidjonovich and RIZAEV Jasur Alimjanovich and ASHUROV Gayur Gafurovich},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2026},
  volume = {11},
  number = {3},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/14746}
}

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