Functional hypothalamic amenorrhea: current insights into pathogenesis, diagnosis, and therapy

AKHMEDJANOVA Saodat Fakhadovna

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2025-yil

Annotatsiya

Functional hypothalamic amenorrhea (FHA) is a common cause of secondary amenorrhea in women of reproductive age, resulting from suppression of gonadotropin-releasing hormone (GnRH) secretion due to stress, energy deficiency, and psychosocial factors. This review summarizes current concepts of FHA pathogenesis, emphasizing the central role of kisspeptin and metabolic hormones in hypothalamic-pituitary-gonadal axis regulation. Clinical manifestations, diagnostic principles, and modern therapeutic strategies are discussed. Particular attention is paid to multidisciplinary approaches aimed at restoring energy balance, reducing stress, and implementing cognitive-behavioral therapy. Emerging treatments, including kisspeptin receptor agonists and leptin-based interventions, show promise for restoring ovulatory function and reproductive health.

Maqola ma’lumotlari
MualliflarAKHMEDJANOVA Saodat Fakhadovna
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2025-12-03
Jild10
Son5
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

функциональная гипоталамическая аменорея, kisspeptin, GnRH, стресс, энергетический дефицит, гипоэстрогения, фертильность, functional hypothalamic amenorrhea, kisspeptin, GnRH, stress, energy deficiency, hypoestrogenism, fertility, funktsional gipotalamik amenoreya, kisspeptin, GnRH, stress, energiya tanqisligi, gipooestrogeniya, fertilitet.

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAAKHMEDJANOVA Saodat Fakhadovna (2025). FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(5). https://tadqiqot.uz/index.php/biomedicine/article/view/13021
GOST (OAK)AKHMEDJANOVA Saodat Fakhadovna FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2025. – T. 10, № 5.
MLAAKHMEDJANOVA Saodat Fakhadovna. “FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(5), 2025. https://tadqiqot.uz/index.php/biomedicine/article/view/13021
ChicagoAKHMEDJANOVA Saodat Fakhadovna. “FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(5) (2025). https://tadqiqot.uz/index.php/biomedicine/article/view/13021
HarvardAKHMEDJANOVA Saodat Fakhadovna (2025) ‘FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(5). https://tadqiqot.uz/index.php/biomedicine/article/view/13021
BibTeX
@article{akhmedjanovasaodatfakhadovna2025,
  title = {FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY},
  author = {AKHMEDJANOVA Saodat Fakhadovna},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2025},
  volume = {10},
  number = {5},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/13021}
}

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