Functional hypothalamic amenorrhea: current insights into pathogenesis, diagnosis, and therapy

Akhmedjanova Saodat Fakhadovna

Klinik fanlar yilnomasi · 2026-yil

Annotatsiya

Functional hypothalamic amenorrhea (FHA) is a common cause of secondary amenorrhea in women of reproductive age, resulting from suppression of gonadotropin-releasing hormone (GnRH) secretion due to stress, energy deficiency, and psychosocial factors. This review summarizes current concepts of FHA pathogenesis, emphasizing the central role of kisspeptin and metabolic hormones in hypothalamic-pituitary-gonadal axis regulation. Clinical manifestations, diagnostic principles, and modern therapeutic strategies are discussed. Particular attention is paid to multidisciplinary approaches aimed at restoring energy balance, reducing stress, and implementing cognitive-behavioral therapy. Emerging treatments, including kisspeptin receptor agonists and leptin-based interventions, show promise for restoring ovulatory function and reproductive health.

Maqola ma’lumotlari
MualliflarAkhmedjanova Saodat Fakhadovna
JurnalKlinik fanlar yilnomasi
NashriyotБухоро давлат тиббиёт институти
ISSN2025-2026, 0009-0006
Nashr sanasi2026-01-21
Jild2
Son4/1
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-26

Maqolaning asl sahifasi

Kalit so‘zlar

functional hypothalamic amenorrhea, kisspeptin, GnRH, stress, energy deficiency, hypoestrogenism, fertility, функциональная гипоталамическая аменорея, kisspeptin, GnRH, стресс, энергетический дефицит, гипоэстрогения, фертильность, funktsional gipotalamik amenoreya, kisspeptin, GnRH, stress, energiya tanqisligi, gipooestrogeniya, fertilitet

Ilmiy soha

Tibbiyot

Iqtibos keltirish

APAAkhmedjanova Saodat Fakhadovna (2026). FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY. Klinik fanlar yilnomasi, 2(4/1). https://tadqiqot.uz/index.php/spjacd/article/view/13176
GOST (OAK)Akhmedjanova Saodat Fakhadovna FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY // Klinik fanlar yilnomasi. – 2026. – T. 2, № 4/1.
MLAAkhmedjanova Saodat Fakhadovna. “FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY.” Klinik fanlar yilnomasi, 2(4/1), 2026. https://tadqiqot.uz/index.php/spjacd/article/view/13176
ChicagoAkhmedjanova Saodat Fakhadovna. “FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY.” Klinik fanlar yilnomasi, 2(4/1) (2026). https://tadqiqot.uz/index.php/spjacd/article/view/13176
HarvardAkhmedjanova Saodat Fakhadovna (2026) ‘FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY’, Klinik fanlar yilnomasi, 2(4/1). https://tadqiqot.uz/index.php/spjacd/article/view/13176
BibTeX
@article{akhmedjanovasaodatfakhadovna2026,
  title = {FUNCTIONAL HYPOTHALAMIC AMENORRHEA: CURRENT INSIGHTS INTO PATHOGENESIS, DIAGNOSIS, AND THERAPY},
  author = {Akhmedjanova Saodat Fakhadovna},
  journal = {Klinik fanlar yilnomasi},
  year = {2026},
  volume = {2},
  number = {4/1},
  url = {https://tadqiqot.uz/index.php/spjacd/article/view/13176}
}

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