Methods of diagnosis and treatment of crohn's disease of the small and large intestine

TOGAYEV Sherkobul Baykobulovich, BAYMAKOV Sayfiddin Risbaevich, HASANOV Bobur Abduganievich, ASHUROV Abdurashid Abdullaevich

Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali · 2025-yil

Annotatsiya

Crohn's Disease (CD) is characterized by a chronic, slowly progressing course, with localization of the pathological process in any part of the gastrointestinal tract. It is typical for young individuals, most frequently affecting the terminal ileum (terminal ileitis) and the proximal part of the colon.OBJECTIVE OF THE STUDY: To develop optimal methods for the diagnosis and treatment of Crohn's disease.MATERIALS AND METHODS:The study involved 94 patients who received inpatient treatment at the Republican Scientific Center of Coloproctology of the Ministry of Health of the Republic of Uzbekistan from 1992 to 2025. Among them were 66 men (70.2%) and 28 women (29.8%). The age of the patients ranged from 30 to 74 years.RESULTS:All patients underwent a course of conservative treatment. In 61 patients (55.9%) with various complications of Crohn's disease, after a short course of conservative therapy aimed at alleviating acute symptoms and taking into account comorbid conditions, various surgical interventions were performed.Indications for surgery included the ineffectiveness of conservative treatment and the presence of complications such as:Bleeding in 18 patients (28.1%)Colonic strictures in 14 patients (21.8%). Enteroenteric fistulas in 3 patients (4.8%).Small intestine strictures in 7 patients (10.9%).Rectal fistulas in 6 patients (9.4%).Colonic pseudopolyposis in 6 patients (9.4%).Toxic colonic dilatation in 2 patients (3.1%).A combination of several complications in 8 patients (12.5%).CONCLUSIONS: In 12.5% of patients with Crohn's disease, a combination of multiple complications was observed. The presence of multiple complications is an absolute indication for surgical intervention.

Maqola ma’lumotlari
MualliflarTOGAYEV Sherkobul Baykobulovich, BAYMAKOV Sayfiddin Risbaevich, HASANOV Bobur Abduganievich, ASHUROV Abdurashid Abdullaevich
JurnalJournal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali
NashriyotТошкент давлат стоматалогия институти, , «Expert Lawyers» MЧЖ
ISSN2181-9300
Nashr sanasi2025-12-03
Jild10
Son5
TilIngliz
Ilmiy sohaTibbiyot
Indeksga qo‘shilgan2026-08-27

Maqolaning asl sahifasi

Kalit so‘zlar

расширение толстой кишки, псевдополипоз, токсическое расширение, toxic dilatation, pseudopolyposis, colonic stricture

Ilmiy soha

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Iqtibos keltirish

APATOGAYEV Sherkobul Baykobulovich, BAYMAKOV Sayfiddin Risbaevich, HASANOV Bobur Abduganievich, & ASHUROV Abdurashid Abdullaevich (2025). METHODS OF DIAGNOSIS AND TREATMENT OF CROHN'S DISEASE OF THE SMALL AND LARGE INTESTINE. Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(5). https://tadqiqot.uz/index.php/biomedicine/article/view/13017
GOST (OAK)TOGAYEV Sherkobul Baykobulovich va b. METHODS OF DIAGNOSIS AND TREATMENT OF CROHN'S DISEASE OF THE SMALL AND LARGE INTESTINE // Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali. – 2025. – T. 10, № 5.
MLATOGAYEV Sherkobul Baykobulovich, BAYMAKOV Sayfiddin Risbaevich, HASANOV Bobur Abduganievich, and ASHUROV Abdurashid Abdullaevich. “METHODS OF DIAGNOSIS AND TREATMENT OF CROHN'S DISEASE OF THE SMALL AND LARGE INTESTINE.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(5), 2025. https://tadqiqot.uz/index.php/biomedicine/article/view/13017
ChicagoTOGAYEV Sherkobul Baykobulovich, BAYMAKOV Sayfiddin Risbaevich, HASANOV Bobur Abduganievich, and ASHUROV Abdurashid Abdullaevich. “METHODS OF DIAGNOSIS AND TREATMENT OF CROHN'S DISEASE OF THE SMALL AND LARGE INTESTINE.” Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(5) (2025). https://tadqiqot.uz/index.php/biomedicine/article/view/13017
HarvardTOGAYEV Sherkobul Baykobulovich, BAYMAKOV Sayfiddin Risbaevich, HASANOV Bobur Abduganievich, and ASHUROV Abdurashid Abdullaevich (2025) ‘METHODS OF DIAGNOSIS AND TREATMENT OF CROHN'S DISEASE OF THE SMALL AND LARGE INTESTINE’, Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali, 10(5). https://tadqiqot.uz/index.php/biomedicine/article/view/13017
BibTeX
@article{togayevsherkobulbaykobulovich2025,
  title = {METHODS OF DIAGNOSIS AND TREATMENT OF CROHN'S DISEASE OF THE SMALL AND LARGE INTESTINE},
  author = {TOGAYEV Sherkobul Baykobulovich and BAYMAKOV Sayfiddin Risbaevich and HASANOV Bobur Abduganievich and ASHUROV Abdurashid Abdullaevich},
  journal = {Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali},
  year = {2025},
  volume = {10},
  number = {5},
  url = {https://tadqiqot.uz/index.php/biomedicine/article/view/13017}
}

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