This review article analyzes the morphological and immunohistochemical criteria of aggressiveness in phyllodes tumors of the breast. Key prognostic parameters-including cellular atypia, mitotic activity, stromal hypercellularity, Ki-67, and p53 expression-are examined in relation to clinical outcomes. Differences in interpretation among authors are highlighted, emphasizing the need for standardized diagnostic criteria and prognostic assessment strategies.
| Mualliflar | KARIMOVA Nargiza Sunnatillayevna, NISHANOV Daniyar Anarbayevich, HASANOV Abduvohid Abdukodirovich |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashr sanasi | 2025-09-08 |
| Jild | 10 |
| Son | 3/2 |
| Til | Rus |
филоидные опухоли, морфология, агрессивность, Ki-67, прогноз, митозы, гиперклеточность, иммуногистохимия., phyllodes tumors, morphology, aggressiveness, Ki-67, prognosis, mitoses, hypercellularity, immunohistochemistry, desmoid o‘smalar, bolalar, morfologiya, CTNNB1, Ki-67, prognoz, davolash
Objective: To analyze lymphocyte subpopulation dynamics and prognostic value in 127 metastatic breast cancer patients with liver involvement undergoing chemoimmunotherapy (2016–2022) at the Samarkand Oncology…
This article provides a modern position on the review of chemotherapy for malignant tumors. Theoretical and practical foundations of the mechanism of action of chemotherapy drugs on normal and tumor cells. Indication…
Today, arthroscopy is the optimal method for the diagnosis and treatment of knee joint injuries. Arthroscopy has made it possible to classify meniscal injuries by morphological types: horizontal, transverse, radial…
This review article examines the morphological features of desmoid tumors in children and their relevance in predicting clinical outcomes. A correlation has been established between cellularity, Ki-67 proliferation…
The article analyzes the factors leading to hip fractures in the elderly. Hip fractures are common in osteoporosis and are often serious, leading to disability and death. Currently our understanding of hip fractures…
This review article presents current perspectives on the morphological spectrum of primary adrenal tumors, with a focus on differential diagnosis, updated classification systems, and immunohistochemical and molecular…
This article presents the main trends in the treatment chronic dislocations of the radial head in children, and also studies the methods of solving this problem by scientists in the world literature. Among the proposed…
Introduction: Analysis of sample allows estimating reserves of the clinical control of a cancer, for example - research of five-year survival depending from a stage of the tumor growth motivates development of practice…
The article presents information about rehabilitation measures at the stage of conservative treatment of congenital hip dislocation in infants. Congenital hip dislocation is one of the most common congenital diseases of…
Introduction: Efficiency of the control of a mammary cancer (МC) is expressed by level of the early diagnostics and the probability of survival of patients on population level. Aim: The efficiency estimation of…
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