This review article examines the morphological features of desmoid tumors in children and their relevance in predicting clinical outcomes. A correlation has been established between cellularity, Ki-67 proliferation index, degree of collagenization, and the risk of local recurrence. Particular emphasis is placed on the S45F mutation of the CTNNB1 gene as an unfavorable prognostic factor. The need for standardization of morphological criteria and implementation of a multidisciplinary approach to treatment is substantiated.
| Mualliflar | NISHANOV Daniyar Anarbayevich, KARIMOVA Nargiza Sunnatillayevna, BOBOYEV Makhsud Maxmudovich |
|---|---|
| Jurnal | Journal of Biomedicine and Practice – Biomeditsina va amaliyot jurnali |
| Nashr sanasi | 2025-09-08 |
| Jild | 10 |
| Son | 3/2 |
| Til | Rus |
десмоидные опухоли, дети, морфология, CTNNB1, Ki-67, прогноз, лечение, desmoid tumors, children, morphology, CTNNB1, Ki-67, prognosis, treatment, desmoid o‘smalar, bolalar, morfologiya, CTNNB1, Ki-67, prognoz, davolash
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