Dilated cardiomyopathy (DCMP) is characterized by left ventricular (LV) dilation or biventricular dilatation with myocardial systolic dysfunction in the absence of hemodynamic overload factors (such as hypertension, valve defects, congenital heart disease) or coronary pathology (such as coronary artery disease) sufficient to cause global systolic dysfunction [1]. The prevalence of DCMP is 36.5 cases per 100,000 people, but among all types of cardiomyopathies, DCMP accounts for 50-60% [2]. DCMP has many known and probably many unexplored causes. Conventionally, they can be divided into genetic and non-genetic. Genetic disorders account for one third of patients with different types of inheritance (autosomal dominant, X-linked, autosomal recessive or mitochondrial.). ); neuromuscular diseases (Duchenne/Becker muscular dystrophies); metabolic diseases, endocrine system diseases and during pregnancy (peripartum period) [3]. Differential diagnosis of PPCM from primary DCM masked by pregnancy is very difficult without molecular genetic studies. This paper describes the results of a comprehensive clinical, instrumental and genetic study using next-generation sequencing (NGS) technologies in two patients with DCM masked by pregnancy.
| Mualliflar | Abdullaev , Timur, Tsoi , Igor, Mirzarakhimova , Saodat, Kuvatov , Anvar, Khudoyberganov , Otabek, Chakova , Natalia, Абдуллаев , Тимур, Цой , Игорь, Мирзарахимова , Саодат, Куватов , Анвар, Худойберганов, Отабек, Чакова , Наталья, Abdullaev , Timur, Tsoi , Igor, Mirzarakhimova , Saodat, Kuvatov , Anvar, Khudoyberganov , Otabek, Chakova , Natalia |
|---|---|
| Jurnal | Жамият ва инновациялар / Общество и инновации / Society and innovations |
| Nashr sanasi | 2024-05-25 |
| Jild | 5 |
| Son | 3 |
| Betlar | 205-212 |
| Til | Rus |
| DOI | 10.47689/2181-1415-vol5-iss3-pp205-212 |
DOI: 10.47689/2181-1415-vol5-iss3-pp205-212 · Maqolaning asl sahifasi
молекулярно-генетическое тестирование, желудочковая тахикардия, ген TTN, МРТ сердца, клинический случай, molecular genetic testing, ventricular tachycardia, TTN gene, cardiac MRI, clinical case
The article analyzes aspects of the liberalization of labor legislation in Uzbekistan within the framework of the State Program "Uzbekistan - 2030". The main focus is on stimulating entrepreneurship and creating jobs…
The article reveals the essence and significance of constitutional reforms at the present stage of legal development of the Republic of Uzbekistan. In this regard, this work will analyze the updated Constitution of the…
The article highlights Thomas Jefferson's contribution to the American independence movement in the 18th century and his role in the formation of the state. Key aspects of his biography, political and legal views, as…
This article discusses the influence of colors on a person’s mood and health, as well as how words affect health. Specific examples are given to show how different colors affect a person's mood and how words can affect…
The article describes the experience of implementing military vocabulary using innovative ways of teaching cadets in practical classes in the Russian language.
The article is devoted to analyzing the influence of family and social environment on the formation of the youth political culture in Uzbekistan. The problems of socialization of youth, methods of solving them, as well…
This article examines the main stages of cooperation between Uzbekistan and Japan, mutually beneficial agreements between these states on the way to increasing the number of tourists on both sides, improving tourism…
The policy of collectivization of agriculture was carried out along with the liquidation of peasant farms, confiscation of their property, and exile of the peasants themselves and their families. The article reveals the…
The article highlights the results of sociological analysis in order to determine the factors that have a positive effect on their activity by studying the lifestyle, socialization, activities and life values of women…
In today's diverse society, multiethnic languages are a strong expression of multiculturalism. This article delves into the intricacies of these languages, exploring their distinctive features, evolution, and social…
Жамият ва инновациялар / Общество и инновации / Society and innovations — barcha maqolalar