Relevance. Takayasu disease (TD) is a systemic inflammatory disease characterized by the involvement of large arteries, primarily the aorta and its branches, and, less frequently, the pulmonary arteries. Purpose of the study.This study presents a comparative analysis of brain-derived neurotrophic factor (BDNF) levels in tear fluid and blood serum in patients with Takayasu disease and carotid artery atherosclerosis. Material and methods. A total of 38 patients were examined, divided into three groups: 15 patients with nonspecific aortoarteriitis (TD), 13 patients with carotid artery atherosclerosis, and 10 healthy individuals. Results. The results showed that BDNF levels in tear fluid and blood serum in patients with Takayasu disease were significantly higher compared to other groups. Conclusion. The data suggest that elevated BDNF levels may serve as an early diagnostic marker for TD, as well as an indicator of the development of ischemic processes, requiring timely diagnosis and treatment.
| Mualliflar | Билалов Э.Н., Миркомилов Э.М., Нарзикулова К.И. |
|---|---|
| Jurnal | Передовая Офтальмология |
| Nashr sanasi | 2025-05-21 |
| Jild | 11 |
| Son | 5 |
| Betlar | 11-14 |
| DOI | 10.57231/j.ao.2024.11.5.002 |
DOI: 10.57231/j.ao.2024.11.5.002 · Maqolaning asl sahifasi · PDF
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